Fluorescent labelling articles within Nature Communications

Featured

• Article
  17 October 2023 | Open Access

  Capturing nascent extracellular vesicles by metabolic glycan labeling-assisted microfluidics

  Temporally sorting EV populations is hard. Here the authors report a microfluidic-based strategy to enable selective isolation of nascent EVs by using azido groups to act as a timestamp for click chemistry labelling: they apply this to mouse models of anti-PD-L1 immunotherapy.

  • Qiuyue Wu
  • , Wencheng Wang
  •  & Yanling Song

• Article
  04 October 2022 | Open Access

  Orthogonally-tunable and ER-targeting fluorophores detect avian influenza virus early infection

  Methods to detect and distinguish the early stage of viral infection often involve complicated and time-consuming protocols. Here, the authors disclose a class of fluorescent molecules that enable fast detection of avian influenza virus infection by selectively localizing at the endoplasmic reticulum in the cell.

  • Taewon Kang
  • , Md Mamunul Haque
  •  & Dongwhan Lee

• Article
  09 April 2021 | Open Access

  Synthetic control over the binding configuration of luminescent sp³-defects in single-walled carbon nanotubes

  Covalent functionalization of single-walled carbon nanotubes with luminescent sp³-defects generally produces a variety of binding configurations and emission wavelengths. The authors propose a base-mediated nucleophilic functionalization approach to selectively achieve configurations for E₁₁* and E₁₁*^- or purely E₁₁*^- defect emission.

  • Simon Settele
  • , Felix J. Berger
  •  & Jana Zaumseil

• Article
  29 October 2020 | Open Access

  Light-induced primary amines and o-nitrobenzyl alcohols cyclization as a versatile photoclick reaction for modular conjugation

  Developing new click chemistry reactions for robust molecular assembly remains challenging. Here the authors report a light-induced primary amines and o-nitrobenzyl alcohols photoclick cyclization for rapid and modular functionalization of small molecules and native biomolecules, in vitro and in living systems.

  • An-Di Guo
  • , Dan Wei
  •  & Xiao-Hua Chen

• Article
  24 July 2020 | Open Access

  Mitochondrial dynamics quantitatively revealed by STED nanoscopy with an enhanced squaraine variant probe

  Live cell imaging of mitochondrial cristae is challenged by the unsuitability of current fluorescent probes and high phototoxicity. Here the authors develop a squarine variant probe (MitoESq-635) that is capable of longitudinal imaging of cristae with STED with minimal phototoxicity.

  • Xusan Yang
  • , Zhigang Yang
  •  & Peng Xi

• Article
  26 February 2018 | Open Access

  The influence of the molecular packing on the room temperature phosphorescence of purely organic luminogens

  Organic luminogens with persistent room temperature phosphorescence will find wide applications in optoelectronic devices and bioimaging, but they are still scarce. Here, the authors synthesize seven organic luminogens and investigate their different properties and potential imaging applications.

  • Jie Yang
  • , Xu Zhen
  •  & Zhen Li

• Article
  08 June 2017 | Open Access

  Spaser as a biological probe

  Advanced diagnostic probes are required for monitoring disease progression. Here Galanzhaet al. demonstrate a 22 nm plasmonic nanolaser to serve as a super-bright, biocompatible probe capable of generating stimulated emission directly inside living cells and animal tissue, while targeting cancer cells.

  • Ekaterina I. Galanzha
  • , Robert Weingold
  •  & Vladimir P. Zharov

• Article | 27 August 2013

  In vivo imaging and histochemistry are combined in the cryosection labelling and intravital microscopy technique

  Imaging cells within live animals is important in biomedical research, but this process is limited by the availability of probes. Ritsma et al.combine intravital microscopy with immunohistochemistry to increase the panel of available reagents and examine the role of T cells in the migration of breast cancer cells.

  • Laila Ritsma
  • , Nienke Vrisekoop
  •  & Jacco van Rheenen