Featured
-
-
Article |
Spo11 generates gaps through concerted cuts at sites of topological stress
Meiotic recombination in yeast is not only initiated by single break sites, but also caused by closely spaced Spo11-dependent double-stranded DNA breaks that create chromosomal gaps.
- Silvia Prieler
- , Doris Chen
- & Franz Klein
-
Article |
Widespread endogenization of giant viruses shapes genomes of green algae
The authors show that large endogenous viral elements derived from giant viruses are prominent components of green algal genomes.
- Mohammad Moniruzzaman
- , Alaina R. Weinheimer
- & Frank O. Aylward
-
Letter |
Non-photosynthetic predators are sister to red algae
Species of the eukaryotic phylum Rhodelphidia are non-photosynthetic, flagellate predators with gene-rich genomes, in contrast to their closely related sister lineage—the red algae—which are immotile, typically photoautotrophic and have relatively small intron-poor genomes and reduced metabolism.
- Ryan M. R. Gawryluk
- , Denis V. Tikhonenkov
- & Patrick J. Keeling
-
Letter |
A widespread coral-infecting apicomplexan with chlorophyll biosynthesis genes
A newly identified lineage of apicomplexans, named corallicolids, are intracellular symbionts of many coral species, and possesses a plastid that retains genes for chlorophyll biosynthesis despite lacking photosystem genes.
- Waldan K. Kwong
- , Javier del Campo
- & Patrick J. Keeling
-
Article |
Creating a functional single-chromosome yeast
Successive fusion of yeast chromosomes is used to produce a single-chromosome strain that is viable, albeit with slightly reduced fitness.
- Yangyang Shao
- , Ning Lu
- & Zhongjun Qin
-
Article |
Endosymbiotic origin and differential loss of eukaryotic genes
Eukaryotes acquired their prokaryotic genes in two episodes of evolutionary influx corresponding to the origin of mitochondria and plastids, respectively, followed by extensive differential gene loss, uncovering a massive imprint of endosymbiosis in the nuclear genomes of complex cells.
- Chuan Ku
- , Shijulal Nelson-Sathi
- & William F. Martin
-
Letter |
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
- Camilla Burnett
- , Sara Valentini
- & David Gems
-
Article |
Driving the cell cycle with a minimal CDK control network
To investigate the core engine of the eukaryotic mitotic cycle, a minimal control network has been generated in fission yeast that efficiently sustains cellular reproduction. Orderly progression through the major events of the cell cycle is driven by oscillation of an engineered minimal CDK module lacking much of the canonical regulation.
- Damien Coudreuse
- & Paul Nurse
Cycles of satellite and transposon evolution in Arabidopsis centromeres