Enzymes articles from across Nature Portfolio

Enzymes catalyze nearly all of the chemical reactions that occur in biological systems. Enzymes are generally proteins but also include catalytic DNA and catalytic RNA. As effective biological catalysts, enzymes work by lowering a reaction’s activation energy barrier, thereby increasing the rate of the reaction. They also improve the specificity of the reactions.


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News and Comment

  • Research Highlights |

    Nitrogenases are enzymes capable of reducing atmospheric nitrogen to ammonia. By better understanding their structure and the reaction mechanism, researchers can work towards artificial mimics that may replace the need for the energy-demanding Haber–Bosch process.

    • Stephanie Greed
  • News & Views |

    The conversion of CO2 into complex molecules by genetically enhanced microorganisms is desirable but challenging. Now, a two-stage strategy featuring carbon sequestration, using the cyanobacterium Synechococcus elongatus, and cellular catalysis, using Escherichia coli, is reported for the synthesis of value-added molecules from CO2.

    • Minrui Ren
    •  & Lennart Schada von Borzyskowski
  • News & Views |

    The selenoprotein glutathione peroxidase 4 (GPX4) is the guardian of ferroptosis, a form of cell death earmarked by unrestrained lipid peroxidation. A new study shows that the metabolic enzyme creatinine kinase B (CKB) phosphorylates GPX4, which may influence the susceptibility of cancer cells to ferroptosis.

    • Eikan Mishima
    •  & Marcus Conrad
    Nature Cell Biology 25, 633-634