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Article
| Open AccessDynamic actuation enhances transport and extends therapeutic lifespan in an implantable drug delivery platform
Drug delivery implants suffer from diminished release profiles due to fibrous capsule formation over time. Here, the authors use soft robotic actuation to modulate the immune response of the host to maintain drug delivery over the longer-term and to perform controlled release in vivo.
- William Whyte
- , Debkalpa Goswami
- & Ellen T. Roche
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Article
| Open AccessHighly efficient and selective extraction of gold by reduced graphene oxide
High extraction capacity with precise selectivity to trace amounts of gold over a wide range of co-existing elements remains a challenge for effective e-waste recycling. Here, authors demonstrate the excellent performance of rGO for gold extraction from e-waste leachate, even at minute concentrations.
- Fei Li
- , Jiuyi Zhu
- & Hui-Ming Cheng
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Article
| Open AccessAdaptive wireless millirobotic locomotion into distal vasculature
Accessibility into the distal vascular systems to treat various diseases remains challenging using medical catheters. Here, Wang et al. demonstrate that a stent-shaped wireless magnetic soft robot enables adaptive locomotion and medical functions into these distal vascular regions.
- Tianlu Wang
- , Halim Ugurlu
- & Metin Sitti
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Article
| Open AccessTropical cyclone-blackout-heatwave compound hazard resilience in a changing climate
The study found that long-duration heatwaves are much more likely to follow power-damaging tropical cyclones in the future RCP8.5 climate, with the impact of longer-than-5-day tropical cyclone-blackout-heatwave compound hazard increasing by a factor of 23 over the 21st century.
- Kairui Feng
- , Min Ouyang
- & Ning Lin
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Article
| Open AccessMicrobial biofilms for electricity generation from water evaporation and power to wearables
Though water evaporation-driven electricity generation is an attractive sustainable energy production strategy, existing electronic devices suffer from poor performance or is costly. Here, the authors report sustainable biofilms for efficient, low-cost evaporation-based electricity production
- Xiaomeng Liu
- , Toshiyuki Ueki
- & Jun Yao
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Article
| Open AccessMetaplastic and energy-efficient biocompatible graphene artificial synaptic transistors for enhanced accuracy neuromorphic computing
Designing biocompatible and flexible electronic devices for neuromrophic applications remains a challenge. Here, Kireev et al. propose graphene-based artificial synaptic transistors with low-energy switching, long-term potentiation, and metaplasticity for future bio-interfaced neural networks.
- Dmitry Kireev
- , Samuel Liu
- & Jean Anne C. Incorvia
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Article
| Open AccessA Transparent Electrode Based on Solution-Processed ZnO for Organic Optoelectronic Devices
A highly conductive and transparent electrode is essential to achieving a high efficiency in indium tin oxide-free optoelectronic devices. Here, the authors strategically prepare sol-gel-grown zinc oxide films based on photoinduced doping effect and demonstrate enhanced performance of devices.
- Zhi Chen
- , Jie Wang
- & Zheng Tang
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Article
| Open AccessEngineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy
Proteolysis targeting chimeras (PROTACs) have emerged as promising cancer therapy agents but have suffered from systemic toxicity issues. Here, the authors report on the creation of polymeric PROTAC nanoparticles for tumour targeting delivery and demonstrate protein degradation in vivo, in combination with photodynamic therapy.
- Jing Gao
- , Bo Hou
- & Haijun Yu
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Article
| Open AccessLead federated neuromorphic learning for wireless edge artificial intelligence
Designing energy-efficient computing solution for the implementation of AI algorithms in edge devices remains a challenge. Yang et al. proposes a decentralized brain-inspired computing method enabling multiple edge devices to collaboratively train a global model without a fixed central coordinator.
- Helin Yang
- , Kwok-Yan Lam
- & H. Vincent Poor
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Article
| Open AccessRevisiting stress-corrosion cracking and hydrogen embrittlement in 7xxx-Al alloys at the near-atomic-scale
High-strength Al alloys are sensitive to stress corrosion cracking and hydrogen embrittlement that limit their applications. Here the authors examine them at near-atomic scale using advanced microscopy and reveal hydrogen at dislocations and grain boundaries, and subsequent microstructural changes.
- Martí López Freixes
- , Xuyang Zhou
- & Baptiste Gault
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Article
| Open AccessUltrastrong and multifunctional aerogels with hyperconnective network of composite polymeric nanofibers
Three-dimensional (3D) microfibrillar network represents an important structural design for various natural tissues and synthetic aerogels but achieving high mechanical properties for synthetic 3D microfibrillar networks remains challenging. Here, the authors report an ultrastrong polymeric aerogels involving self-assembled 3D networks of aramid nanofiber composites with high nodal connectivity.
- Huimin He
- , Xi Wei
- & Lizhi Xu
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Article
| Open AccessLong-range charge carrier mobility in metal halide perovskite thin-films and single crystals via transient photo-conductivity
Charge carrier mobility is a fundamental property of semiconductors. The authors of this study demonstrate a novel way to estimate long-range mobilities of perovskite thin-films and single crystals by taking early-time carrier dynamics into account.
- Jongchul Lim
- , Manuel Kober-Czerny
- & Henry J. Snaith
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Article
| Open AccessHigh-throughput fabrication of soft magneto-origami machines
Machines capable of magnetically controllable shape morphing and locomotion have diverse promising applications. Here, authors propose a scalable fabrication strategy that transforms 2D magnetic sheets into 3D soft magneto-active machines with customized geometries by incorporating origami folding.
- Shengzhu Yi
- , Liu Wang
- & Lelun Jiang
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Article
| Open AccessMilli-scale cellular robots that can reconfigure morphologies and behaviors simultaneously
Modular robots with reconfigurable architectures show advantages in unpredicted environments. Here Yang et al. propose a heterogeneous assembly concept for cellular robot construction at millimeter scales, which can simultaneously reconfigure their morphologies and behaviours to conduct versatile tasks on demand.
- Xiong Yang
- , Rong Tan
- & Yajing Shen
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Article
| Open AccessBioinspired asymmetric amphiphilic surface for triboelectric enhanced efficient water harvesting
The effective acquisition of clean water from atmospheric water offers a potential sustainable solution for increasing global water shortages. Here, authors developed a bioinspired asymmetric amphiphilic surface incorporating self-driven triboelectric adsorption to obtain clean water.
- Song Zhang
- , Mingchao Chi
- & Shuangxi Nie
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Article
| Open AccessActuating compact wearable augmented reality devices by multifunctional artificial muscle
Artificial muscle actuators enabled by responsive functional materials like shape memory alloys are promising candidates for compact e-wearable devices. Here, authors demonstrate augmented reality glasses and two-way communication haptic gloves capable of image depth control and immersive tactile response.
- Dongjin Kim
- , Baekgyeom Kim
- & Je-Sung Koh
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Article
| Open AccessSpongy all-in-liquid materials by in-situ formation of emulsions at oil-water interfaces
All-in-liquid printing promises applications from energy storage to drug delivery and tissue engineering. Here, authors present the in-situ generation of layered emulsion in a fraction of a second at the oil-water interface forming 3D tube-like structures in a liquid medium.
- Parisa Bazazi
- , Howard A. Stone
- & S. Hossein Hejazi
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Article
| Open AccessSuper-broadband on-chip continuous spectral translation unlocking coherent optical communications beyond conventional telecom bands
Continuous spectral translation could allow expansion of the bandwidth available for communication without having to develop transceivers for the new bands. Here, the authors demonstrate this using AlGaAsOI nanowaveguides as spectral translators between the mature telecom C band and the 2-μm wavelength band.
- Deming Kong
- , Yong Liu
- & Hao Hu
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Article
| Open AccessBuilding programmable multicompartment artificial cells incorporating remotely activated protein channels using microfluidics and acoustic levitation
Engineering micro-emulsion plays a key role in the creation of bottom-up synthetic cells. Here, authors demonstrate a droplet laboratory platform to control membrane protein gating in functional artificial cell using microfluidics and acoustic levitation.
- Jin Li
- , William D. Jamieson
- & David A. Barrow
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Article
| Open AccessPartial freezing of rat livers extends preservation time by 5-fold
The limited preservation duration of donor organs is a big problem. Here the authors report a method for the freezing of whole rat livers at temperatures between −10 °C to −15 °C for up to 5 days, based on freeze-tolerant wood frogs, and term this partial freezing.
- Shannon N. Tessier
- , Reinier J. de Vries
- & Mehmet Toner
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Article
| Open AccessMechanical intelligence for learning embodied sensor-object relationships
Information-based search strategies are relevant for the learning of interacting agents dynamics and usually need predefined data. The authors propose a method to collect data for learning a predictive sensor model, without requiring domain knowledge, human input, or previously existing data.
- Ahalya Prabhakar
- & Todd Murphey
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Article
| Open AccessDecapod-inspired pigment modulation for active building facades
Typical buildings are static structures, unable to adjust to dynamic temperature and daylight fluctuations. Here, authors present an adaptive alternative, using shape-tuneable pigment injections to control solar ingress and reduce estimated building energy use by 30%.
- Raphael Kay
- , Charlie Katrycz
- & Benjamin D. Hatton
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Article
| Open AccessFabrication of triboelectric polymer films via repeated rheological forging for ultrahigh surface charge density
High charge density is the foundation to promote a wide range of applications of triboelectric nanogenerators. Here, authors propose a processing method based on the repeated rheological forging of triboelectric polymers achieving an enhanced triboelectricity and further study its mechanism.
- Zhaoqi Liu
- , Yunzhi Huang
- & Jin-Ping Qu
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Article
| Open AccessLocal bifurcation with spin-transfer torque in superparamagnetic tunnel junctions
There has been much interest in using the probabilistic switching of magnetic tunnel junctions in unconventional computing, but to do so requires a detailed understanding of this switching. Here, Funatsu et al rigorously determine the switching exponents in superparamagnetic tunnel junctions.
- Takuya Funatsu
- , Shun Kanai
- & Hideo Ohno
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Article
| Open AccessElectric-field control of nonlinear THz spintronic emitters
Spintronic terahertz (THz) emitters are a class of magnetic heterostructure where femtosecond laser excitations generate THz radiation emission. While they have great potential, electric field control of spintronic emitter remains a challenge. Here, by combining a spintronic emitter with a piezoelectric substrate, Agarwal et al. demonstrate electric field control of THz emission through induced piezostrain.
- Piyush Agarwal
- , Lisen Huang
- & Ranjan Singh
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Article
| Open AccessCluster-type analogue memristor by engineering redox dynamics for high-performance neuromorphic computing
Conventional filamentary memristors are limited in dynamics by the high electric-field dependence of the conductive filament. Here, Jeong et al. presents a method which creates a cluster-type memristor, enabling large conductance range and long data retention.
- Jaehyun Kang
- , Taeyoon Kim
- & YeonJoo Jeong
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Article
| Open AccessProgrammable CRISPR-Cas9 microneedle patch for long-term capture and real-time monitoring of universal cell-free DNA
Real-time sensing of biomarkers via the use of wearable devices is a major aim of personalised medicine. Here, authors demonstrate an on-line wearable microneedle patch for real-time capture and monitoring of universal cell-free DNA.
- Bin Yang
- , Jilie Kong
- & Xueen Fang
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Article
| Open AccessAll-fibre heterogeneously-integrated frequency comb generation using silicon core fibre
Silicon core fibre is a highly nonlinear waveguide that combines the benefits of both fibre and planar waveguide systems. Here, the authors demonstrate frequency comb generation using a fully-fibre integrated silicon core fibre as a nonlinear mixer.
- Ronit Sohanpal
- , Haonan Ren
- & Zhixin Liu
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Article
| Open AccessProbing interlayer shear thermal deformation in atomically-thin van der Waals layered materials
Van der Waals materials exhibit unique thermomechanical properties, but interlayer deformations are usually challenging to measure. Here, the authors exploit the strain-dependent optical properties of monolayer WSe2 to quantitatively probe the interlayer shear thermal deformations and interlayer coupling in phosphorene and hexagonal boron nitride.
- Le Zhang
- , Han Wang
- & Xiaolong Chen
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Article
| Open AccessA calibratable sensory neuron based on epitaxial VO2 for spike-based neuromorphic multisensory system
A highly efficient hardware element capable of sensing and encoding multiple physical signals is still lacking. Here, the authors report a spike-based neuromorphic perception system consisting of tunable and highly uniform artificial sensory neurons based on epitaxial VO2 capable of hand gesture classification.
- Rui Yuan
- , Qingxi Duan
- & Yuchao Yang
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Article
| Open AccessHighly robust and soft biohybrid mechanoluminescence for optical signaling and illumination
Despite the advantages of biohybrid systems for soft robotics, most systems have short lifetime, require complex fabrication, and only remain functional with careful maintenance. Here, the authors report biohybrid mechanoluminescence in soft elastomer-encapsulated bioluminescent dinoflagellates.
- Chenghai Li
- , Qiguang He
- & Shengqiang Cai
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Article
| Open AccessUltra-wide bandgap semiconductor Ga2O3 power diodes
The simultaneous achievement of high breakdown voltage and low resistance is a contradictory point because it would require high and low doping simultaneously. Here, Zhou et al. achieve a power figure-of-merit of 13.2 GW/cm2 through hole injection and conductivity modulation effect.
- Jincheng Zhang
- , Pengfei Dong
- & Yue Hao
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Article
| Open AccessFlexible ultrasound-induced retinal stimulating piezo-arrays for biomimetic visual prostheses
Electronic visual prostheses, or biomimetic eyes, have shown capability of restoring functional vision through electrical pulses artificially initiating neural responses. Here, authors demonstrate a flexible piezo-array for ultrasound-induced retinal stimulation.
- Laiming Jiang
- , Gengxi Lu
- & Qifa Zhou
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Article
| Open AccessStructure induced laminar vortices control anomalous dispersion in porous media
Most porous systems comprise structures characterized by dead-end and transmitting pores. Here, authors show that macroscopic transport through such porous medium is controlled by structure-induced laminar vortices inside each dead-end pore, and such cannot be explained by diffusion alone.
- Ankur Deep Bordoloi
- , David Scheidweiler
- & Pietro de Anna
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Article
| Open AccessSolvent-driven fractional crystallization for atom-efficient separation of metal salts from permanent magnet leachates
Rare earth elements are essential to electrified infrastructure and clean energy production. Here, authors show reagent- and energy-efficient separation of lanthanides from secondary feedstock using dimethyl ether-driven fractional crystallization.
- Caleb Stetson
- , Denis Prodius
- & Aaron D. Wilson
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Article
| Open AccessOptimised weight programming for analogue memory-based deep neural networks
Device-level complexity represents a big shortcoming for the hardware realization of analogue memory-based deep neural networks. Mackin et al. report a generalized computational framework, translating software-trained weights into analogue hardware weights, to minimise inference accuracy degradation.
- Charles Mackin
- , Malte J. Rasch
- & Geoffrey W. Burr
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Article
| Open AccessVoltage-driven gigahertz frequency tuning of spin Hall nano-oscillators
Spin-hall nano-oscillators are a variation on spin-torque nano-oscillators, where the spin-Hall effect is used to drive oscillations, however past examples have had limited frequency tunability. Here, Choi et al demonstrate spin-hall oscillators with wide voltage controlled frequency tunability.
- Jong-Guk Choi
- , Jaehyeon Park
- & Byong-Guk Park
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Article
| Open AccessUpcycling Compact Discs for Flexible and Stretchable Bioelectronic Applications
Electronic waste is a global issue brought about by the short lifespan of electronics. Here, the authors report a process to upcycle compact discs into flexible and stretchable bio-electronics.
- Matthew S. Brown
- , Louis Somma
- & Ahyeon Koh
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Article
| Open AccessTailoring the metal electrode morphology via electrochemical protocol optimization for long-lasting aqueous zinc batteries
Long-lasting zinc metal electrodes are crucial in developing commercial zinc-based batteries. Here, the authors investigate the different morphology evolution between the stripping and plating process and propose electrochemical protocols to prolong the lifespan of zinc anodes.
- Qing Li
- , Ao Chen
- & Chunyi Zhi
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Article
| Open AccessLight-induced charge generation in polymeric nanoparticles restores vision in advanced-stage retinitis pigmentosa rats
Retinal dystrophies such as Retinitis pigmentosa are among the most prevalent causes of inherited incurable legal blindness. Here the authors demonstrate that conjugated polymer nanoparticles reinstate visual functions in aged rats with fully degenerated and rewired retinas.
- S. Francia
- , D. Shmal
- & F. Benfenati
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Article
| Open AccessPOLYRETINA restores light responses in vivo in blind Göttingen minipigs
Retinal prostheses hold potential for artificial vision in blind people. Here, authors show that POLYRETINA, a large and high-density photovoltaic epiretinal device, restores light-evoked cortical responses in blind Göttingen minipigs at safe irradiance levels.
- Paola Vagni
- , Marta Jole Ildelfonsa Airaghi Leccardi
- & Diego Ghezzi
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Article
| Open AccessDecoupled temperature and pressure hydrothermal synthesis of carbon sub-micron spheres from cellulose
Temperature and pressure are typically dependent parameters in hydrothermal processes. Here, authors devise a hydrothermal system that allows independent control of these parameters and realize low-temperature fast synthesis of carbon sub-micron spheres directly from cellulose at higher pressure.
- Shijie Yu
- , Xinyue Dong
- & Hui Zhou
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Article
| Open AccessIn situ 3D bioprinting with bioconcrete bioink
Bioinks used in current in-situ bioprinting have limitations when applied to complex operational environments. Here, the authors report on the creation of a microgel reinforced GelMA bioink which can be simply prepared and used in different biomedical settings. The application is demonstrated in a cranial defect model.
- Mingjun Xie
- , Yang Shi
- & Yong He
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Article
| Open AccessHigh stress twinning in a compositionally complex steel of very high stacking fault energy
Mechanical twinning is difficult to trigger in face centered cubic alloys with high stacking fault energies (SFEs) under standard tensile loading. Here, the authors report high stress twinning in a bulk compositionally complex steel of very high SFE, enhancing the material’s mechanical performance.
- Zhangwei Wang
- , Wenjun Lu
- & Zhiming Li
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Article
| Open AccessGeometry-independent antenna based on Epsilon-near-zero medium
This paper proposes an unconventional type of antennas that are composed by epsilon-near-zero (ENZ) media. The operating frequencies of such antennas are independent of their geometries, and are determined by material dispersion.
- Hao Li
- , Ziheng Zhou
- & Nader Engheta
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Article
| Open AccessMeeting sustainable development goals via robotics and autonomous systems
A horizon scan was used to explore possible impacts of robotics and automated systems on achieving the UN Sustainable Development Goals. Positive effects are likely. Iterative regulatory processes and continued dialogue could help avoid environmental damages and increases in inequality.
- Solène Guenat
- , Phil Purnell
- & Martin Dallimer
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Article
| Open AccessCyclic microchip assay for measurement of hundreds of functional proteins in single neurons
Current single-cell tools are limited by the number of proteins they can analyse. Here the authors report a single-cell cyclic multiplex in situ tagging (CycMIST) method for functional proteome profiling of single cells, allowing multiple rounds of multiplexing of the same single cells on a microchip.
- Liwei Yang
- , Avery Ball
- & Jun Wang
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Article
| Open AccessCurrent-induced self-switching of perpendicular magnetization in CoPt single layer
One challenge for spin-based electronics is the controlled and reliable switching of magnetization without magnetic fields. Here, Liu et al investigate a variety of compositions of CoPt, and determine the specific composition to maximize switching performance, potentially simplifying device design.
- Liang Liu
- , Chenghang Zhou
- & Jingsheng Chen
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Article
| Open AccessAugmented ultrasonography with implanted CMOS electronic motes
Ultrasound has had tremendous success in medical imaging. Here, Zhang et al demonstrate a batteryless implantable CMOS mote, to further augment the potential of ultrasound, providing additional information via the backscattering of the acoustic waves used in ultrasound imaging.
- Yihan Zhang
- , Prashant Muthuraman
- & Kenneth L. Shepard