Endometrial cancer

Endometrial cancer is a type of tumour that arises in the tissue lining the uterus. Most endometrial cancers are adenocarcinomas; that is, cancers formed from cells that make and release mucus and other fluids.

Latest Research and Reviews

Research
18 February 2021 | Open Access

YBX2 and cancer testis antigen 45 contribute to stemness, chemoresistance and a high degree of malignancy in human endometrial cancer
- Izumi Suzuki
- , Sachiko Yoshida
- & Kiyoko Kato
Scientific Reports 11, 4220
Research
11 February 2021 | Open Access

Diagnostic accuracy of cytology for the detection of endometrial cancer in urine and vaginal samples

Postmenopausal bleeding can be an indication of endometrial cancer. Here, the authors combine cytology of urine and vaginal samples from women with postmenopausal bleeding and demonstrate that they can accurately predict endometrial cancer with a sensitivity of 91.7% and specificity of 88.8%.
- Helena O’Flynn
- , Neil A. J. Ryan
- & Emma J. Crosbie
Nature Communications 12, 952
Research | 03 February 2021

Reproducibility of scoring criteria for HER2 immunohistochemistry in endometrial serous carcinoma: a multi-institutional interobserver agreement study
- Natalia Buza
- , Elizabeth D. Euscher
- & Pei Hui
Modern Pathology, 1-9
Research
12 January 2021 | Open Access

Two-port access for laparoscopic surgery for endometrial cancer using conventional laparoscopic instruments
- Kuan-Ju Huang
- , Ying-Xuan Li
- & Wen-Chun Chang
Scientific Reports 11, 615
Research
08 January 2021 | Open Access

Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer
- Yinan Xiao
- , Ling Jin
- & Viji Shridhar
Oncogene, 1-16
Research | 16 December 2020

Computed tomography chest imaging offers no advantage over chest X-ray in the initial assessment of gestational trophoblastic neoplasia
- Victoria L. Parker
- , Matthew C. Winter
- & Robert F. Harrison
British Journal of Cancer, 1-6

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News and Comment

Comments & Opinion | 06 July 2020

Polygenic risk score opportunities for early detection and prevention strategies in endometrial cancer
- Tracy A. O’Mara
- & Emma J. Crosbie
British Journal of Cancer 123, 1045-1046
News & Views | 31 May 2018

Steps towards effective gynaecological cancer screening

PapSEEK, a novel liquid-based cytology test, enabled the highly specific detection of endometrial and ovarian cancer in a retrospective study. Herein, I discuss potential applications of this tool, both for cancer screening of asymptomatic populations and for the early diagnosis of cancer in symptomatic women.
- Usha Menon
Nature Reviews Clinical Oncology 15, 538-540
Research Highlights | 24 April 2018

Pap seeking new challenges

Wang et al. have developed a diagnostic tool (based on the widely used Papanicolaou (Pap) test) to detect endometrial and ovarian cancer in patients by using PCR-based analyses of genetic mutations and aneuploidy.
- Ulrike Harjes
Nature Reviews Cancer 18, 338-339
Research Highlights | 12 May 2017

Puberty timing and cancer risk
- David Holmes
Nature Reviews Endocrinology 13, 377
Research Highlights | 21 February 2017

SLN staging for endometrial cancer
- David Killock
Nature Reviews Clinical Oncology 14, 200
Research Highlights | 14 May 2013

New classification for endometrial cancer puts genes in POLE position
- Rebecca Kirk
Nature Reviews Clinical Oncology 10, 304

All News & Comment

Endometrial cancer

Latest Research and Reviews

YBX2 and cancer testis antigen 45 contribute to stemness, chemoresistance and a high degree of malignancy in human endometrial cancer

Diagnostic accuracy of cytology for the detection of endometrial cancer in urine and vaginal samples

Reproducibility of scoring criteria for HER2 immunohistochemistry in endometrial serous carcinoma: a multi-institutional interobserver agreement study

Two-port access for laparoscopic surgery for endometrial cancer using conventional laparoscopic instruments

Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer

Computed tomography chest imaging offers no advantage over chest X-ray in the initial assessment of gestational trophoblastic neoplasia

News and Comment

Polygenic risk score opportunities for early detection and prevention strategies in endometrial cancer

Steps towards effective gynaecological cancer screening

Pap seeking new challenges

Puberty timing and cancer risk

SLN staging for endometrial cancer

New classification for endometrial cancer puts genes in POLE position

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