Nature

ELISA articles from across Nature Portfolio

The enzyme-linked immunosorbent assay (ELISA) is a sensitive method to quantify or test for the presence of antigen or ligand. Enzyme-linked antibodies (or ligand binding proteins) are used to bind an analyte on a solid substrate, and convert a colourless reporter molecule to a coloured or luminescent product for detection.

Latest Research and Reviews

A bead-based multiplex assay covering all coronaviruses pathogenic for humans for sensitive and specific surveillance of SARS-CoV-2 humoral immunity
- Daniel Stern
- Tanja C. Meyer
- Brigitte G. Dorner
ResearchOpen Access09 Dec 2023 Scientific Reports
Volume: 13, P: 21846
Development of a sandwich ELISA to detect circulating, soluble IRAP as a potential disease biomarker
- Anika Vear
- Claudia Thalmann
- Siew Yeen Chai
ResearchOpen Access24 Nov 2023 Scientific Reports
Volume: 13, P: 17565
The evaluation of five serological assays in determining seroconversion to peste des petits ruminants virus in typical and atypical hosts
- Matthew Tully
- Carrie Batten
- Richard Kock
ResearchOpen Access08 Sept 2023 Scientific Reports
Volume: 13, P: 14787
Novel methods of immunogenic antigen selection for serological diagnosis of Parelaphostrongylus tenuis infection
- Jessie Richards
- Stephen Kania
- Richard Gerhold
ResearchOpen Access07 Jul 2023 Scientific Reports
Volume: 13, P: 10989
Application of ultrasensitive digital ELISA for p24 enables improved evaluation of HIV-1 reservoir diversity and growth kinetics in viral outgrowth assays
- Yury V. Kuzmichev
- Carol Lackman-Smith
- Deanna A. Kulpa
ResearchOpen Access06 Jul 2023 Scientific Reports
Volume: 13, P: 10958
Hybrid immunity in older adults is associated with reduced SARS-CoV-2 infections following BNT162b2 COVID-19 immunisation

Pallett, Heskin et al. monitor longitudinal response in older adults following vaccination with the BNT162b2 COVID-19 (Pfizer-BioNTech) vaccination. Hybrid immunity is associated with higher antibody titres, neutralisation and inhibition capacity.
- Scott J. C. Pallett
- Joseph Heskin
- Luke S. P. Moore
ResearchOpen Access16 Jun 2023 Communications Medicine
Volume: 3, P: 83

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News and Comment

ACPA epitopes — what are we actually looking at?

The use of assays to detect anti-citrullinated protein antibodies (ACPAs) is helpful in the diagnosis of rheumatoid arthritis. But how good are these assays at detecting ACPAs and do we really know what the results are telling us about ACPA specificity?
- Lotte A. van de Stadt
- Theo Rispens
News & Views09 Jan 2019 Nature Reviews Rheumatology
Volume: 15, P: 130-132
Do PR3-ANCA levels predict relapse?
- Joana Osório
Research Highlights03 Mar 2016 Nature Reviews Rheumatology
Volume: 12, P: 192
Naked-eye ELISA developed

Research Highlights31 Oct 2012 Nature
Volume: 491, P: 10-11
An assay panel for the diagnosis of SLE

Research Highlights11 Sept 2012 Nature Reviews Rheumatology
Volume: 8, P: 562
Pneumococcal glycoconjugate vaccines produce antibody responses that strongly correlate with function
- Paul V. Licciardi
- Anne Balloch
- Mimi L.K. Tang
Correspondence29 Apr 2011 Nature Reviews Drug Discovery
Volume: 10, P: 393

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