Electrophysiology articles from across Nature Portfolio

Electrophysiology is the measurement and characterization of the electrical properties of cells and tissues, particularly neurons and neuronal tissue.

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Research
25 May 2023 | Open Access

Compensatory mechanisms of reduced interhemispheric EEG connectivity during sleep in patients with apnea
- Maksim Zhuravlev
- , Mikhail Agaltsov
- & Anastasiya Runnova
Scientific Reports 13, 8444
Research
23 May 2023 | Open Access

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

Stings of certain ant species can cause intense, long-lasting nociception. Here, authors show that the major contributors of these symptoms are vertebrate-selective defensive venom peptides which modulate the activity of voltage-gated sodium channels.
- Samuel D. Robinson
- , Jennifer R. Deuis
- & Irina Vetter
Nature Communications 14, 2977
Research
18 May 2023 | Open Access

An organ-on-chip device with integrated charge sensors and recording microelectrodes
- Hande Aydogmus
- , Michel Hu
- & Massimo Mastrangeli
Scientific Reports 13, 8062
Research
11 May 2023 | Open Access

TMS-EEG perturbation biomarkers for Alzheimer’s disease patients classification
- Alexandra-Maria Tăuƫan
- , Elias P. Casula
- & Emiliano Santarnecchi
Scientific Reports 13, 7667
Research
11 May 2023 | Open Access

Vesicular glutamate transporters are H⁺-anion exchangers that operate at variable stoichiometry

In glutamatergic neurons, synaptic vesicles contain glutamate, but not aspartate. Here, the authors show that vesicular glutamate transporters are H+/anion exchangers that attain high selectivity for glutamate via variable transport coupling.
- Bettina Kolen
- , Bart Borghans
- & Christoph Fahlke
Nature Communications 14, 2723
Research
11 May 2023 | Open Access

Two single-point mutations in Ankyrin Repeat one drastically change the threshold temperature of TRPV1

TRPV1 is a noxious heat sensor. Here, authors showed that tailed amphibians express TRPV1 with a reduced heat-activation threshold by substitution of two amino acids in the N-terminal region to contribute to cool-habitat selection.
- Shogo Hori
- , Michihiro Tateyama
- & Osamu Saitoh
Nature Communications 14, 2415

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News and Comment

Research Highlights | 12 April 2023

In situ generation of electrodes
- Nina Vogt
Nature Methods 20, 482
News & Views | 15 March 2023

Profiling the Ca²⁺ spark dynamics in live cardiomyocytes

Calcium sparks are the elementary detectable units of calcium release through ryanodine receptors (RyRs). Hou et al. correlate Ca²⁺ sparks with RyR cluster configurations and provide insights into the dynamics of Ca²⁺ release in live cardiomyocytes at baseline and in pathological conditions.
- Laetitia Pereira
- , Almudena Val-Blasco
- & Ana M. Gómez
Nature Cardiovascular Research 2, 225-226
News & Views | 21 February 2023

Recording single-neuron activity during walking in humans

We developed a wearable platform (the Neuro-stack) for recording single-neuron and local field potentials in freely moving humans. The Neuro-stack enabled the recording of single-neuron activity during walking behavior in humans. The platform also enables personalized stimulation during real-time decoding of neural activity, which can potentially improve neurostimulation treatments.

Nature Neuroscience 26, 377-378
News & Views | 14 November 2022

Cardiac Ca²⁺ current is ‘Rad’-ically altered by adrenergic activation

The rapid enhancement of cardiac Ca²⁺ current (I_Ca,L) is central to enhanced heart function during the sympathetic fight-or-flight response. A new study shows how the small GTPase Rad mediates tonic I_Ca,L inhibition that is relieved after PKA-dependent phosphorylation of Rad, which causes release of Rad from the Ca²⁺ channel and increased I_Ca,L.
- Donald M. Bers
Nature Cardiovascular Research 1, 980-981
News & Views | 17 October 2022

Channelosome and intracellular K⁺ channels in arrhythmia

Mutations in Kir2.1 resulting in defects in trafficking to the cardiomyocyte sarcolemma promote arrhythmia in Anderson–Tawil syndrome. Macias and colleagues provide a dual mechanism underlying cardiac arrhythmia that involves chaperoning of voltage-gated Na⁺ channels and a unique population of intracellular Kir2.1 channels that regulate Ca²⁺ cycling at the sarcoplasmic reticulum.
- Ibra Fancher
- & Irena Levitan
Nature Cardiovascular Research 1, 874-875
Research Highlights | 08 March 2022

Poverty impacts infant brains
- Shari Wiseman
Nature Neuroscience 25, 267

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Electrophysiology articles from across Nature Portfolio

Latest Research and Reviews

Compensatory mechanisms of reduced interhemispheric EEG connectivity during sleep in patients with apnea

Ant venoms contain vertebrate-selective pain-causing sodium channel toxins

An organ-on-chip device with integrated charge sensors and recording microelectrodes

TMS-EEG perturbation biomarkers for Alzheimer’s disease patients classification

Vesicular glutamate transporters are H⁺-anion exchangers that operate at variable stoichiometry

Two single-point mutations in Ankyrin Repeat one drastically change the threshold temperature of TRPV1

News and Comment

In situ generation of electrodes

Profiling the Ca²⁺ spark dynamics in live cardiomyocytes

Recording single-neuron activity during walking in humans

Cardiac Ca²⁺ current is ‘Rad’-ically altered by adrenergic activation

Channelosome and intracellular K⁺ channels in arrhythmia

Poverty impacts infant brains

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Electrophysiology articles from across Nature Portfolio

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