DNA sequencing
DNA sequencing is any chemical, enzymatic or technological procedure for determining the linear order of nucleotide bases in DNA. Sanger sequencing by replicative synthesis in the presence of dideoxy nucleotide chain terminator monomers has now given way to 'next generation' sequencing by short parallel read technologies. The term often applies to the entire sequence determination pipeline including post-sequencing software analysis.
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sortChIC enables detailed chromatin analysis of rare cell typesLatest Research and Reviews
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Research
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Reference-free lossless compression of nanopore sequencing reads using an approximate assembly approach
Scientific Reports 13, 2082 -
Research
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Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
Nature Genetics, 1-14 -
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Research
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Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
Nature Communications 14, 77 -
Reference-free lossless compression of nanopore sequencing reads using an approximate assembly approach
Notch1 mutations drive clonal expansion in normal esophageal epithelium but impair tumor growth
Navigating the pitfalls of mapping DNA and RNA modifications
De novo genome assembly and analyses of 12 founder inbred lines provide insights into maize heterosis
Germline TP53 mutations undergo copy number gain years prior to tumor diagnosis
Comparison of DNA extraction methods on CITES-listed timber species and application in species authentication of commercial products using DNA barcoding
Dads older than mums since dawn of humanity, study suggests
Long-read sequencing in the era of epigenomics and epitranscriptomics
Method of the year: long-read sequencing