DNA nanotechnology articles within Nature

Featured

  • Article
    | Open Access

    Examination of nucleation during self-assembly of multicomponent structures illustrates how ubiquitous molecular phenomena inherently classify high-dimensional patterns of concentrations in a manner similar to neural network computation.

    • Constantine Glen Evans
    • , Jackson O’Brien
    •  & Arvind Murugan

  • Article |

    A method is presented to harness the paper-folding mechanism of reconfigurable macroscale systems to create reconfigurable DNA origami structures, in anticipation that it will advance the development of complex molecular systems.

    • Myoungseok Kim
    • , Chanseok Lee
    •  & Do-Nyun Kim

  • Article
    | Open Access

    The authors introduce a single-molecule DNA-barcoding method, resolution enhancement by sequential imaging, that improves the resolution of fluorescence microscopy down to the Ångström scale using off-the-shelf fluorescence microscopy hardware and reagents.

    • Susanne C. M. Reinhardt
    • , Luciano A. Masullo
    •  & Ralf Jungmann

  • Article |

     Mimicking traditional digital neural networks with DNA-encoded ‘enzymatic’ neurons overcomes issues with other chemical approaches, and could allow notable increases in miniaturization and molecular implementation of these AI models, with potential applications including DNA data storage or cancer diagnosis.

    • S. Okumura
    • , G. Gines
    •  & A. J. Genot

  • Article |

    Preparing crystals held together with macromolecular bonds can create shape memory materials that can be engineered to exhibit a wide range of reversible changes useful for chemical sensing, optics and robotics.

    • Seungkyu Lee
    • , Heather A. Calcaterra
    •  & Chad A. Mirkin

  • Article
    | Open Access

    A nanoscale rotary motor made of DNA origami, driven by ratcheting and powered by an external electric field, shows the ability to wind up a spring and has mechanical capabilities approaching those of biological motors.

    • Anna-Katharina Pumm
    • , Wouter Engelen
    •  & Hendrik Dietz

  • Letter |

    A set of 355 self-assembling DNA ‘tiles’ can be reprogrammed to implement many different computer algorithms—including sorting, palindrome testing and divisibility by three—suggesting that molecular self-assembly could be a reliable algorithmic component in programmable chemical systems.

    • Damien Woods
    • , David Doty
    •  & Erik Winfree

  • Letter |

    By using DNA sequence information to encode the shapes of DNA origami building blocks, shape-programmable assemblies can be created, with sizes and complexities similar to those of viruses.

    • Klaus F. Wagenbauer
    • , Christian Sigl
    •  & Hendrik Dietz

  • Letter |

    All necessary strands for DNA origami can be created in a single scalable process by using bacteriophages to generate single-stranded precursor DNA containing the target sequences interleaved with self-excising DNA enzymes.

    • Florian Praetorius
    • , Benjamin Kick
    •  & Hendrik Dietz

  • Letter |

    The incorporation of large numbers of chemically diverse functional components into microfabricated structures at precise locations is challenging; now the precision placement of DNA origami by directed self-assembly is shown to overcome this problem for the purpose of reliably and controllably coupling molecular emitters to photonic crystal cavities.

    • Ashwin Gopinath
    • , Evan Miyazono
    •  & Paul W. K. Rothemund

  • Letter |

    Probing the assembly process that occurs when single-stranded DNA is folded into desired shapes by ‘DNA origami’ shows that it can be guided by controlling the strengths of local and long-range interactions, enabling more reproducible synthesis.

    • Katherine E. Dunn
    • , Frits Dannenberg
    •  & Jonathan Bath

  • Letter |

    A general method of folding arbitrary polygonal digital meshes in DNA uses a routeing algorithm based on graph theory and a relaxation simulation that traces scaffold strands through the target structures to produce complex structures with an open conformation that are stable under biological assay conditions.

    • Erik Benson
    • , Abdulmelik Mohammed
    •  & Björn Högberg

  • Letter |

    An efficient and scalable strategy with robust error correction is reported for encoding a record amount of information (including images, text and audio files) in DNA strands; a ‘DNA archive’ has been synthesized, shipped from the USA to Germany, sequenced and the information read.

    • Nick Goldman
    • , Paul Bertone
    •  & Ewan Birney

  • News & Views |

    DNA is the material of choice for making custom-designed, nanoscale shapes and patterns through self-assembly. A new technique revisits old ideas to enable the rapid prototyping of more than 100 such DNA shapes. See Letter p.623

    • Paul W. K. Rothemund
    •  & Ebbe Sloth Andersen

  • News & Views |

    The ligand-mediated binding of colloid particles to each other is more effective if the particles are flat rather than curved. This finding opens up opportunities for the design of self-assembling materials.

    • Sharon C. Glotzer

  • News & Views |

    Robots have to store lots of information in order to coordinate their actions, but how can this be done for nanometre-scale robots? One answer is to program data into the robots' environment instead.

    • Lloyd M. Smith

  • News Feature |

    Chemists looking to create complex self-assembling nanostructures are turning to DNA. Katharine Sanderson looks at the science beneath the fold.

    • Katharine Sanderson

Browse broader subjects

Browse narrower subjects

Browse DNA nanotechnology across other nature.com journals