Diseases articles from across Nature Portfolio

Diseases are abnormal conditions that have a specific set of signs and symptoms. Diseases can have an external cause, such as an infection, or an internal cause, such as autoimmune diseases.

Featured

News & Views | 01 June 2023

β2-Microglobulin boosts β-amyloid aggregation and neurotoxicity in an Alzheimer’s disease model

Nature Neuroscience, 1-2
News & Views | 30 May 2023

Zooming into process-specific risk
- Hannah Maude
- & Inês Cebola
Nature Metabolism 5, 730-731
News & Views | 23 May 2023

Etrasimod for ulcerative colitis: evaluating phase III results
- Katsuyoshi Matsuoka
- & Toshifumi Hibi
Nature Reviews Gastroenterology & Hepatology, 1-2

Latest Research and Reviews

Research
03 June 2023 | Open Access

Anemia as a risk factor for disease progression in patients admitted for COVID-19: data from a large, multicenter cohort study
- Nicola Veronese
- , Francesco Vladimiro Segala
- & Annalisa Saracino
Scientific Reports 13, 9035
Research
03 June 2023 | Open Access

Tocilizumab-induced hypofibrinogenemia in patients with systemic-onset juvenile idiopathic arthritis
- Tingyan He
- , Jiayun Ling
- & Jun Yang
Scientific Reports 13, 9050
Research
03 June 2023 | Open Access

Internet addiction and residual depressive symptoms among clinically stable adolescents with major psychiatric disorders during the COVID-19 pandemic: a network analysis perspective
- Hong Cai
- , Yan-Jie Zhao
- & Yu-Tao Xiang
Translational Psychiatry 13, 186
Research
03 June 2023 | Open Access

METTL3-dependent m⁶A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling
- Shuo Wan
- , Yadong Sun
- & Meixiang Yang
Cell Death & Disease 14, 349
Research
03 June 2023 | Open Access

Stress-responsive Gdf15 counteracts renointestinal toxicity via autophagic and microbiota reprogramming

Stress-responsive Growth Differentiation Factor 15 controls acute renointestinal distress by facilitating mucin production and cellular protection via reorganization of cell-protective autophagic signalling and muco-regulatory microbiota in mice.
- Navin Ray
- , Seung Jun Park
- & Yuseok Moon
Communications Biology 6, 602
Research
03 June 2023 | Open Access

An IL-17-EGFR-TRAF4 axis contributes to the alleviation of lung inflammation in severe influenza

Adaptive transfer experiments using an influenza hemagglutinin antigen-specific mouse model suggest that viral neuraminidase-activated TGF-β from Th1 cells guides Th17 evolution to promote protection from lung inflammation in severe influenza.
- Avijit Dutta
- , Chen-Yiu Hung
- & Ching-Tai Huang
Communications Biology 6, 600

All Research & Reviews

News and Comment

Correspondence | 03 June 2023

A common factor? Sleep, macular degeneration and neurodegenerative disease
- Brandon Stretton
- , Joshua G Kovoor
- & Weng Onn Chan
Eye, 1
Research Highlights | 02 June 2023

Extracellular vesicles key in liver metastasis
- Ian Fyfe
Nature Reviews Gastroenterology & Hepatology, 1
Research Highlights | 02 June 2023

Combination treatment further extends survival
- Ian Fyfe
Nature Reviews Gastroenterology & Hepatology, 1
Research Highlights | 02 June 2023

AI predicts pancreatic cancer risk
- Ian Fyfe
Nature Reviews Gastroenterology & Hepatology, 1
Research Highlights | 02 June 2023

Docking on SERT reveals new inhibitors
- M. Teresa Villanueva
Nature Reviews Drug Discovery
News & Views | 01 June 2023

β2-Microglobulin boosts β-amyloid aggregation and neurotoxicity in an Alzheimer’s disease model

β2-Microglobulin (β₂M) is an amyloidogenic protein. β₂M coaggregates with β-amyloid (Aβ) in the brains of patients with Alzheimer’s disease and enhances Aβ deposition. β₂M is essential for Aβ neurotoxicity in vivo, and neutralization of pathogenetic β₂M–Aβ aggregates ameliorates the amyloid pathology and cognitive deficits associated with disease in a mouse model.

Nature Neuroscience, 1-2

All News & Comment

Diseases articles from across Nature Portfolio

Featured

β2-Microglobulin boosts β-amyloid aggregation and neurotoxicity in an Alzheimer’s disease model

Zooming into process-specific risk

Etrasimod for ulcerative colitis: evaluating phase III results

Latest Research and Reviews

Anemia as a risk factor for disease progression in patients admitted for COVID-19: data from a large, multicenter cohort study

Tocilizumab-induced hypofibrinogenemia in patients with systemic-onset juvenile idiopathic arthritis

Internet addiction and residual depressive symptoms among clinically stable adolescents with major psychiatric disorders during the COVID-19 pandemic: a network analysis perspective

METTL3-dependent m⁶A methylation facilitates uterine receptivity and female fertility via balancing estrogen and progesterone signaling

Stress-responsive Gdf15 counteracts renointestinal toxicity via autophagic and microbiota reprogramming

An IL-17-EGFR-TRAF4 axis contributes to the alleviation of lung inflammation in severe influenza

News and Comment

A common factor? Sleep, macular degeneration and neurodegenerative disease

Extracellular vesicles key in liver metastasis

Combination treatment further extends survival

AI predicts pancreatic cancer risk

Docking on SERT reveals new inhibitors

β2-Microglobulin boosts β-amyloid aggregation and neurotoxicity in an Alzheimer’s disease model

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Diseases articles from across Nature Portfolio

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