Diabetes complications articles from across Nature Portfolio

Diabetes complications are disorders that arise as a result of the patient having diabetes. The high blood sugar levels that often present in patients with diabetes cause damage to various tissues and organs, which increases the risk of cardiovascular disease and can result in disorders such as diabetic retinopathy.

Latest Research and Reviews

Research
15 May 2023 | Open Access

DNA methylation markers for kidney function and progression of diabetic kidney disease

Epigenetic markers are potential biomarkers for diabetes and related complications. Here, the authors identify CpG sites associated with kidney function and its subsequent decline using both single-site and multisite analyses, which are shown to have functional significance in the kidney.
- Kelly Yichen Li
- , Claudia Ha Ting Tam
- & Ronald C. W. Ma
Nature Communications 14, 2543
Research
01 May 2023 | Open Access

Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity
- Si Shi
- , Huijie Gu
- & Lixia Lu
Experimental & Molecular Medicine 55, 898-909
Research | 21 April 2023

Infographic: Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation in patients with proliferative diabetic retinopathy (PDR): the CLARITY study
- Imran H. Yusuf
- , Christin Henein
- & Sobha Sivaprasad
Eye, 1-2
Research
28 February 2023 | Open Access

Daily phytate intake increases adiponectin levels among patients with diabetes type 2: a randomized crossover trial
- Pilar Sanchis
- , Paula Calvo
- & Luis Masmiquel
Nutrition & Diabetes 13, 2
Research
24 February 2023 | Open Access

Imaging biomarkers and clinical factors associated with the rate of progressive inner and outer retinal thinning in patients with diabetic macular edema
- Enrico Borrelli
- , Costanza Barresi
- & Giuseppe Querques
Scientific Reports 13, 3224
Research
20 February 2023 | Open Access

Socioeconomic inequality in awareness, treatment and control of diabetes among adults in India: Evidence from National Family Health Survey of India (NFHS), 2019–2021
- Suraj Maiti
- , Shamrin Akhtar
- & Sanjay K. Mohanty
Scientific Reports 13, 2971

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News and Comment

Research Highlights | 13 February 2023

Serine slows diabetic neuropathy in mice
- Shimona Starling
Nature Reviews Endocrinology 19, 187
Research Highlights | 10 February 2023

The effect of long-term statin use on diabetic nephropathy
- Claire Greenhill
Nature Reviews Endocrinology 19, 189
News & Views | 20 October 2022

Diagnosis of gestational diabetes mellitus: the debate continues

A randomized controlled trial demonstrates that using lower glycaemic criteria for diagnosing and treating gestational diabetes mellitus than currently used increases disease prevalence but does not reduce the risk of large-for-gestational-age infants across a population. However, individuals with mild hyperglycaemia who would otherwise remain undiagnosed experienced important health benefits from treatment.
- Aoife M. Egan
- & Fidelma P. Dunne
Nature Reviews Endocrinology 18, 723-724
Correspondence | 08 June 2022

Bone fragility in type 2 diabetes mellitus: a lot left to explore
- Rimesh Pal
- , Trupti N. Prasad
- & Sanjay K. Bhadada
Nature Reviews Endocrinology 18, 651
News & Views | 08 June 2022

Novel mechanisms of pain in painful diabetic neuropathy

A recent study has generated compelling experimental data on the role of GPR177 and WNT5a in the pathogenesis and treatment of painful diabetic neuropathy (PDN). The clinical value of these translational findings should be interpreted with caution. However, the limited efficacy of current treatments for PDN warrants further clinical studies on these novel pathways.
- Rayaz A. Malik
Nature Reviews Endocrinology 18, 459-460
News & Views | 09 May 2022

Visualizing heterogeneity in type 2 diabetes phenotype, outcome and drug response

Phenotypic heterogeneity in type 2 diabetes (T2D) was visualized by non-linear dimensionality reduction in a cohort of over 23,000 people. Variation in the T2D phenotype mapped to variation in drug response, risk of disease complications and underlying genetic architecture.

Nature Medicine 28, 909-910

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Diabetes complications articles from across Nature Portfolio

Latest Research and Reviews

DNA methylation markers for kidney function and progression of diabetic kidney disease

Glia maturation factor beta deficiency protects against diabetic osteoporosis by suppressing osteoclast hyperactivity

Infographic: Clinical efficacy of intravitreal aflibercept versus panretinal photocoagulation in patients with proliferative diabetic retinopathy (PDR): the CLARITY study

Daily phytate intake increases adiponectin levels among patients with diabetes type 2: a randomized crossover trial

Imaging biomarkers and clinical factors associated with the rate of progressive inner and outer retinal thinning in patients with diabetic macular edema

Socioeconomic inequality in awareness, treatment and control of diabetes among adults in India: Evidence from National Family Health Survey of India (NFHS), 2019–2021

News and Comment

Serine slows diabetic neuropathy in mice

The effect of long-term statin use on diabetic nephropathy

Diagnosis of gestational diabetes mellitus: the debate continues

Bone fragility in type 2 diabetes mellitus: a lot left to explore

Novel mechanisms of pain in painful diabetic neuropathy

Visualizing heterogeneity in type 2 diabetes phenotype, outcome and drug response

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