Cytokinesis articles within Nature

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• Letter | 15 March 2017

  Transmission of cytokinesis forces via E-cadherin dilution and actomyosin flows

  Under physiological forces, resulting from cytokinesis, the mechanosensitivity of adherens junction arises from a local decrease in E-cadherin concentration and results in actomyosin flows.

  • Diana Pinheiro
  • , Edouard Hannezo
  •  & Yohanns Bellaïche

• Letter | 13 July 2015

  Kinetochore-localized PP1–Sds22 couples chromosome segregation to polar relaxation

  A study of division in proliferating animal cells points to the existence of a kinetochore-based signalling pathway, independent of furrow formation, centrosomes and microtubules, that couples chromosome segregation to cell division.

  • Nelio T. L. Rodrigues
  • , Sergey Lekomtsev
  •  & Buzz Baum

• Letter | 26 November 2014

  MapZ marks the division sites and positions FtsZ rings in Streptococcus pneumoniae

  A new mechanism is identified for correct placement of the division machinery in Streptococcus pneumoniae that relies on the novel factor MapZ to form ring structures at the cell equator; these structures move apart as the cell elongates, acting as permanent markers of division sites.

  • Aurore Fleurie
  • , Christian Lesterlin
  •  & Christophe Grangeasse

• Letter | 12 December 2012

  Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis

  Structural and functional analysis of the centralspindlin complex shows that it connects the mitotic spindle to the plasma membrane during cytokinesis through interactions of the C1 domain of centralspindlin’s MgcRacGAP subunit with phosphoinositide lipids.

  • Sergey Lekomtsev
  • , Kuan-Chung Su
  •  & Mark Petronczki

• Letter | 07 August 2011

  Polar actomyosin contractility destabilizes the position of the cytokinetic furrow

  • Jakub Sedzinski
  • , Maté Biro
  •  & Ewa Paluch

• Letter | 22 September 2010

  The ploidy conveyor of mature hepatocytes as a source of genetic variation

  Cells that make up the liver are known to be polyploid. These authors show that mouse hepatocytes can increase and decrease their ploidy in vivo; increases occur as a result of failed cytokinesis, and decreases occur as a result of multipolar mitosis. The resulting genetic heterogeneity might be advantageous following hepatic injury, allowing the selection of 'genetically robust' cells from a pre-existing pool of diverse genotypes.

  • Andrew W. Duncan
  • , Matthew H. Taylor
  •  & Markus Grompe