Cortex articles from across Nature Portfolio

The cortex refers to the outermost layer of the cerebral hemispheres or cerebrum. The cerebral cortex in humans is folded into gyri and consists of six horizontal layers of neurons, with distinct connections among the layers and neuronal subtypes of cells.

Latest Research and Reviews

Research
31 May 2023 | Open Access

Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex

Electrophysiological recordings in rats reveal that the hippocampal CA1 region represents learning-related action and reward events faster than the lateral entorhinal cortex.
- Shogo Soma
- , Shinya Ohara
- & Yoshikazu Isomura
Communications Biology 6, 584
Research
24 May 2023 | Open Access

Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner

How the brain controls pain perception remains elusive. Here, authors show that layers 5 and 6 of the somatosensory cortex suppress or enhance nociception through cell-type-specific cortical and corticothalamic interactions.
- Katharina Ziegler
- , Ross Folkard
- & Alexander Groh
Nature Communications 14, 2999
Research
19 May 2023 | Open Access

A rapid theta network mechanism for flexible information encoding

Filtering or gating relevant information into working memory has been attributed to the striatum. Here, the authors reveal neocortical filtering mechanisms, namely, rapid changes in oscillatory theta networks, that predict fast and flexible human behavior.
- Elizabeth L. Johnson
- , Jack J. Lin
- & David Badre
Nature Communications 14, 2872
Research
12 May 2023 | Open Access

Changes in perceived peripersonal space following the rubber hand illusion
- M. Smit
- , H. C. Dijkerman
- & M. J. van der Smagt
Scientific Reports 13, 7713
Research
11 May 2023 | Open Access

Distinct nonlinear spectrotemporal integration in primary and secondary auditory cortices
- Amber M. Kline
- , Destinee A. Aponte
- & Hiroyuki K. Kato
Scientific Reports 13, 7658
Research
11 May 2023 | Open Access

Task-specific modulation of corticospinal neuron activity during motor learning in mice

Corticospinal activity is temporally coded with precise movements in mice. Here the authors investigate the role of corticospinal neuron activity in motor cortex during the learning of either a precise or imprecise task.
- Najet Serradj
- , Francesca Marino
- & Edmund Hollis
Nature Communications 14, 2708

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News and Comment

News & Views | 06 April 2023

Fear memory engram is the mind-killer

Stegemann et al. have unraveled a long-lasting role for fear engrams in future pain perception. Prefrontal pain and fear representations become entangled following a fearful event. As subsequent painful experiences also reactivate the fear network, silencing the fear engram alone can alleviate both tonic pain and hypersensitivity in chronic pain.
- Clément Pouget
- & Gisella Vetere
Nature Neuroscience 26, 729-731
News & Views | 22 December 2022

Deep reinforcement learning to study combinatorial expansion of a behavior repertoire

Despite rich behavioral evidence, it is unclear how the brain expands its behavior repertoire. By building theoretical models with a deep reinforcement learning algorithm, I show that the brain composes a behavior to solve a novel task by combining previously acquired skills and augmenting their variability.

Nature Neuroscience 26, 2-3
Comments & Opinion | 01 September 2022

Neurocognitive and motor-control challenges for the realization of bionic augmentation

Robotic fingers and arms that augment the motor abilities of non-disabled individuals are increasingly feasible yet face neurocognitive barriers and hurdles in efferent motor control.
- Tamar R. Makin
- , Silvestro Micera
- & Lee E. Miller
Nature Biomedical Engineering 7, 344-348
Research Highlights | 01 August 2022

How sound soothes
- Shari Wiseman
Nature Neuroscience 25, 977
Research Highlights | 08 December 2021

Step by step consolidation

Selective and transient erasure of LTP reveals the roles of synaptic plasticity at multiple stages of memory consolidation.
- Katherine Whalley
Nature Reviews Neuroscience 23, 68-69
Research Highlights | 27 October 2021

A peptidergic disinhibitory microcircuit

Gastrin-releasing peptide (GRP) signalling regulates vasoactive-intestinal peptide (VIP)-expressing cortical cells in a disinhibitory microcircuit that modulates a cortex-dependent behaviour.
- Jake Rogers
Nature Reviews Neuroscience 22, 719

All News & Comment

Cortex articles from across Nature Portfolio

Latest Research and Reviews

Rat hippocampal CA1 region represents learning-related action and reward events with shorter latency than the lateral entorhinal cortex

Primary somatosensory cortex bidirectionally modulates sensory gain and nociceptive behavior in a layer-specific manner

A rapid theta network mechanism for flexible information encoding

Changes in perceived peripersonal space following the rubber hand illusion

Distinct nonlinear spectrotemporal integration in primary and secondary auditory cortices

Task-specific modulation of corticospinal neuron activity during motor learning in mice

News and Comment

Fear memory engram is the mind-killer

Deep reinforcement learning to study combinatorial expansion of a behavior repertoire

Neurocognitive and motor-control challenges for the realization of bionic augmentation

How sound soothes

Step by step consolidation

A peptidergic disinhibitory microcircuit

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