Communication and replication

Communication is the transfer of data between data sources and data sinks, and replication is the copying of data from one server to another. Communication and replication are important in database maintenance and preservation of data.

Latest Research and Reviews

Research
09 February 2022 | Open Access

Versioning biological cells for trustworthy cell engineering

Full traceability and transparency are important to establish trust in engineered cell lines. Here the authors argue that version control for cell engineering marks a significant step toward more open, reproducible, traceable and ultimately more trustworthy engineering biology.
- Jonathan Tellechea-Luzardo
- , Leanne Hobbs
- & Natalio Krasnogor
Nature Communications 13, 765
Research
11 January 2022 | Open Access

InterCellar enables interactive analysis and exploration of cell−cell communication in single-cell transcriptomic data

Marta Interlandi et al. develop InterCellar, a user-friendly tool for analyzing ligand−receptor interactions from scRNA-seq data, and establishing a link between these interactions and well-known molecular pathways.
- Marta Interlandi
- , Kornelius Kerl
- & Martin Dugas
Communications Biology 5, 21
Research
27 December 2021 | Open Access

Utilizing DeepSqueak for automatic detection and classification of mammalian vocalizations: a case study on primate vocalizations
- Daniel Romero-Mujalli
- , Tjard Bergmann
- & Marina Scheumann
Scientific Reports 11, 24463
Research
12 November 2021 | Open Access

Mesmerize is a dynamically adaptable user-friendly analysis platform for 2D and 3D calcium imaging data

Calcium imaging is valuable for understanding neuro and cell biology, but is challenging to analyze, organize, and access. Here, the authors present an efficient, expandable and user-friendly platform, which encapsulates the entire analysis process all to way to interactive visualizations.
- Kushal Kolar
- , Daniel Dondorp
- & Marios Chatzigeorgiou
Nature Communications 12, 6569
Reviews | 24 May 2021

Tutorial: guidelines for annotating single-cell transcriptomic maps using automated and manual methods

This tutorial provides guidelines for interpreting single-cell transcriptomic maps to identify cell types, states and other biologically relevant patterns.
- Zoe A. Clarke
- , Tallulah S. Andrews
- & Gary D. Bader
Nature Protocols 16, 2749-2764
Research
10 February 2021 | Open Access

Replication dynamics of recombination-dependent replication forks

Replication forks that are stalled at obstacles on the DNA template can be restarted by homologous recombination. Here, the authors show replication dynamics during homologous recombination-dependent replication fork restart by combining polymerase usage sequencing and a Monte Carlo mathematical model.
- Karel Naiman
- , Eduard Campillo-Funollet
- & Antony M. Carr
Nature Communications 12, 923

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News and Comment

Comments & Opinion | 09 September 2020

Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist

Here we present the MI-CLAIM checklist, a tool intended to improve transparent reporting of AI algorithms in medicine.
- Beau Norgeot
- , Giorgio Quer
- & Atul J. Butte
Nature Medicine 26, 1320-1324
Comments & Opinion
12 December 2019 | Open Access

Experiment design driven FAIRification of omics data matrices, an exemplar

We outline a principled approach to data FAIRification rooted in the notions of experimental design, and whose main intent is to clarify the semantics of data matrices. Using two related metabolomics datasets associated to journal articles, we perform retrospective data and metadata curation and re-annotation, using community, open, interoperability standards. The results are semantically-anchored data matrices, deposited in public archives, which are readable by software agents for data-level queries, and which can support the reproducibility and reuse of the data underpinning the publications.
- Philippe Rocca-Serra
- & Susanna-Assunta Sansone
Scientific Data 6, 271
Editorial | 12 July 2017

Wanted: biotech for an aging population

Digital medicine's extraordinary ability to communicate with patients, especially in under-served communities, could help reorient the biotech industry to better address aging and its associated diseases.

Nature Biotechnology 35, 597
News | 05 June 2014

Cryptographic methods enable analyses without privacy breaches
- Nicholette Zeliadt
Nature Medicine 20, 563
News | 10 August 2012

New media

British Dental Journal 213, 100
News | 01 September 2010

Design of data figures
- Bang Wong
Nature Methods 7, 665

All News & Comment

Communication and replication

Latest Research and Reviews

Versioning biological cells for trustworthy cell engineering

InterCellar enables interactive analysis and exploration of cell−cell communication in single-cell transcriptomic data

Utilizing DeepSqueak for automatic detection and classification of mammalian vocalizations: a case study on primate vocalizations

Mesmerize is a dynamically adaptable user-friendly analysis platform for 2D and 3D calcium imaging data

Tutorial: guidelines for annotating single-cell transcriptomic maps using automated and manual methods

Replication dynamics of recombination-dependent replication forks

News and Comment

Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist

Experiment design driven FAIRification of omics data matrices, an exemplar

Wanted: biotech for an aging population

Cryptographic methods enable analyses without privacy breaches

New media

Design of data figures

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