• Article |

    A new methodology for the discovery of chalcogenides by tuning the temperature and flux ratios of systems using mixed fluxes is demonstrated, leading to the synthesis of 30 new and unreported compounds or compositions.

    • Xiuquan Zhou
    • , Venkata Surya Chaitanya Kolluru
    •  & Mercouri G. Kanatzidis
  • Article |

    An electron transfer mechanism that involves a light-triggered geometric conversion between metal and oxygen redox chemistry shows superior performance compared with approaches that use either metal or oxygen redox chemistry.

    • Xiaopeng Wang
    • , Shibo Xi
    •  & Junmin Xue
  • Article |

    Nanometre-sized ‘nanoglue’ islands of CeOx on high-surface-area SiO2 are shown to suppress sintering and confine on average one Pt atom per island, leading to stable single-atom catalysts under oxidizing and reducing environments.

    • Xu Li
    • , Xavier Isidro Pereira-Hernández
    •  & Jingyue Liu
  • Article |

    DNA-mediated assembly of hollow nanoparticles can be used in an edge-bonding approach to design and synthesize nanoscale open-channel superlattices, with control of symmetry, geometry and topology.

    • Yuanwei Li
    • , Wenjie Zhou
    •  & Chad A. Mirkin
  • Article |

    A molecular ratchet, in which a crown ether is pumped from solution onto an encoded molecular strand by a pulse of chemical fuel, opens the way for the reading of information along molecular tapes.

    • Yansong Ren
    • , Romain Jamagne
    •  & David A. Leigh
  • Article |

    Preparing crystals held together with macromolecular bonds can create shape memory materials that can be engineered to exhibit a wide range of reversible changes useful for chemical sensing, optics and robotics.

    • Seungkyu Lee
    • , Heather A. Calcaterra
    •  & Chad A. Mirkin
  • Article |

    NMR spectroscopy has been used to guide the directed evolution of myoglobin to a Kemp eliminase with high catalytic efficiency, outlining an approach that is likely to be generally applicable to other enzyme activities.

    • Sagar Bhattacharya
    • , Eleonora G. Margheritis
    •  & Ivan V. Korendovych
  • Article |

    An air purification strategy is presented that moves air in the form of bubbles through an ion-doped conjugated polymer-coated matrix, which captures larger particulate matter, infiltrated with a selected functional liquid, which captures smaller particulate matter.

    • Yunmao Zhang
    • , Yuhang Han
    •  & Xu Hou
  • Article |

    Triplet photoenzymes developed through genetic encoding and directed evolution result in excited-state photocatalysts that provide a valuable approach to enantioselective photochemical synthesis.

    • Ningning Sun
    • , Jianjian Huang
    •  & Yuzhou Wu
  • Article |

    A genetically encoded triplet photosensitizer is used to develop an efficient photoenzyme that can promote enantioselective intramolecular and bimolecular [2+2] cycloadditions by means of triplet energy transfer.

    • Jonathan S. Trimble
    • , Rebecca Crawshaw
    •  & Anthony P. Green
  • Article |

    A bacteriogenic strategy for constructing membrane-bounded, molecularly crowded, and compositionally, structurally and morphologically complex synthetic cells provides opportunities for the fabrication of new synthetic cell modules and augmented living/synthetic cell constructs.

    • Can Xu
    • , Nicolas Martin
    •  & Stephen Mann
  • Article
    | Open Access

    A fluorescent molecule is described that does not follow Hund’s rule and instead shows singlet and triplet excited states with inverted energy levels, leading to high-efficiency OLEDs with potential implications for optoelectronic devices.

    • Naoya Aizawa
    • , Yong-Jin Pu
    •  & Daigo Miyajima
  • Article |

    Catalysts consisting of oxide-supported pair sites can enable bifunctional reaction mechanisms with high activity and selectivity for reactions and so overcome the limitations in industry imposed by the use of homogeneous catalysts.

    • Insoo Ro
    • , Ji Qi
    •  & Phillip Christopher
  • Article
    | Open Access

    Analysis of atmospheric data on two enantiomerically separated forms of monoterpene from a controlled drought and rewetting experiment in an enclosed tropical rainforest ecosystem showed distinct diel emission peaks, regulated by different production pathways.

    • Joseph Byron
    • , Juergen Kreuzwieser
    •  & Jonathan Williams
  • Article |

    A reaction is described combining oxidative polymerization and in situ reductive n-doping to yield poly(benzodifurandione), a facilely synthesized stable n-type conducting polymer with ultrahigh conductivity, with applications in organic electronics.

    • Haoran Tang
    • , Yuanying Liang
    •  & Fei Huang
  • Article |

     The analytical workflow outlined in this study allows multiple crude reaction mixtures to be analysed simultaneously, with substantial reductions in method development and analysis time, and maximizes the chances of finding catalytic systems with broad substrate scope.

    • Corin C. Wagen
    • , Spencer E. McMinn
    •  & Eric N. Jacobsen
  • Article |

    Using a molecular catalyst and a proton–electron transfer mediator in tandem delivers efficient electroreduction of nitrogen to ammonia at modest potentials, an approach that could be used to improve other important reactions.

    • Pablo Garrido-Barros
    • , Joseph Derosa
    •  & Jonas C. Peters
  • Article
    | Open Access

    Selectively functionalized macrocycles were synthesized with reactivities that preferentially aligned to create well-defined pores across an ultrathin nanofilm offering a strategy to create subnanometre channels in polymer membranes, and demonstrating potential for accurate molecular separations.

    • Zhiwei Jiang
    • , Ruijiao Dong
    •  & Andrew G. Livingston
  • Article |

    Modification of the internal and external surface chemistry of microporous zeolite and metal–organic framework nanocrystals leads to a generalizable strategy to aqueous porous liquids and impart high gas-carrying capacities to liquid water.

    • Daniel P. Erdosy
    • , Malia B. Wenny
    •  & Jarad A. Mason
  • Article |

    Oxidative cleavage of alkenes is achieved using nitroarenes and light irradiation as an alternative to using ozone to break the carbon–carbon bonds, avoiding the explosive intermediates formed with ozone.

    • Alessandro Ruffoni
    • , Charlotte Hampton
    •  & Daniele Leonori
  • Article |

    A highly chemoselective and enantioselective cross-electrophile coupling using ‘ene’-reductases is reported, and photoexcited enzymes demonstrate the ability to carry out reactions between electrophiles that are not known for small-molecule catalysis.

    • Haigen Fu
    • , Jingzhe Cao
    •  & Todd K. Hyster
  • Article |

    A high-efficiency, robust process using a high-concentration imide-based lithium-salt electrolyte enables the electroreduction of nitrogen with stabilized ammonia yield rates of 150 ± 20 nmol s−1  cm−2 and a current-to-ammonia efficiency that is close to 100%.

    • Hoang-Long Du
    • , Manjunath Chatti
    •  & Alexandr N. Simonov
  • Article |

    Concerted proton–electron transfer mediators enable facile electrochemical metal hydride formation and thus improve CO2 reduction to useful chemicals, and could benefit a range of catalytic reactions involving metal hydride intermediates.

    • Subal Dey
    • , Fabio Masero
    •  & Victor Mougel
  • Article |

    Iron atoms in a synthetic metal–sulfur cluster can capture nitrogen and catalyse its silylation, demonstrating successful nitrogen reduction by iron atoms in a sulfur-rich environment.

    • Yasuhiro Ohki
    • , Kenichiro Munakata
    •  & Kazuki Tanifuji
  • Article |

    A metal–organic framework membrane based on fumarate and mesaconate linkers is shown to have a pore aperture shape that enables efficient and cost-effective removal of nitrogen and carbon dioxide from methane.

    • Sheng Zhou
    • , Osama Shekhah
    •  & Mohamed Eddaoudi
  • Article |

    A study demonstrates the rational de novo design of water-soluble assemblies constructed from long 310-helical peptides, and details their characterization by circular dichroism spectroscopy, analytical ultracentrifugation and X-ray crystallography.

    • Prasun Kumar
    • , Neil G. Paterson
    •  & Derek N. Woolfson
  • Article |

    Using an interlayer bonding cleavage strategy, a two-dimensional monolayer fullerene network is prepared; its moderate bandgap makes it a potential candidate for use in two-dimensional electronic devices.

    • Lingxiang Hou
    • , Xueping Cui
    •  & Jian Zheng
  • Review Article |

    Recent progress in computational enzyme design, active site engineering and directed evolution are reviewed, highlighting methodological innovations needed to deliver improved designer biocatalysts.

    • Sarah L. Lovelock
    • , Rebecca Crawshaw
    •  & Anthony P. Green
  • Article
    | Open Access

    By performing experiments under upper tropospheric conditions, nitric acid, sulfuric acid and ammonia can form particles synergistically, at rates orders of magnitude faster than any two of the three components.

    • Mingyi Wang
    • , Mao Xiao
    •  & Neil M. Donahue
  • Article |

    A synthetic route to GB18, an alkaloid from the bark of hallucinogenic Galbulimima sp., is developed, enabling its identification as an antagonist of κ- and μ-opioid receptors.

    • Stone Woo
    •  & Ryan A. Shenvi