Featured
-
-
Article
| Open AccessBODIPY-Based Fluorescent Probes for Sensing Protein Surface-Hydrophobicity
- Nethaniah Dorh
- , Shilei Zhu
- & Ashutosh Tiwari
-
Article
| Open Access“Cation-Stitching Cascade”: exquisite control of terpene cyclization in cyclooctatin biosynthesis
- Hajime Sato
- , Kazuya Teramoto
- & Masanobu Uchiyama
-
Article
| Open AccessNovel mechanism of harmaline on inducing G2/M cell cycle arrest and apoptosis by up-regulating Fas/FasL in SGC-7901 cells
- Yihai Wang
- , Chunhua Wang
- & Xiangjiu He
-
Article
| Open AccessMinimal domain of bacterial phytochrome required for chromophore binding and fluorescence
- Konstantin A. Rumyantsev
- , Daria M. Shcherbakova
- & Vladislav V. Verkhusha
-
Article
| Open AccessDiscovery of novel INK4C small-molecule inhibitors to promote human and murine hematopoietic stem cell ex vivo expansion
- Xiang-Qun Xie
- , Peng Yang
- & Yingdai Gao
-
Article
| Open AccessPRINT: A Protein Bioconjugation Method with Exquisite N-terminal Specificity
- Surojit Sur
- , Yuan Qiao
- & Shibin Zhou
-
Article
| Open AccessGC-elements controlling HRAS transcription form i-motif structures unfolded by heterogeneous ribonucleoprotein particle A1
- Giulia Miglietta
- , Susanna Cogoi
- & Luigi E. Xodo
-
Article
| Open AccessGFP-complementation assay to detect functional CPP and protein delivery into living cells
- Nadia Milech
- , Brooke AC Longville
- & Richard M Hopkins
-
Article
| Open AccessPerturbation of cellular proteostasis networks identifies pathways that modulate precursor and intermediate but not mature levels of frataxin
- Joseph F. Nabhan
- , Renea L. Gooch
- & Christine E. Bulawa
-
Article
| Open Access6-Amidopyrene as a label-assisted laser desorption/ionization (LA-LDI) enhancing tag: development of photoaffinity pyrene derivative
- Kozo Yoneda
- , Yaping Hu
- & Hideo Kigoshi
-
Article
| Open AccessResistance Mechanisms and Molecular Docking Studies of Four Novel QoI Fungicides in Peronophythora litchii
- Yuxin Zhou
- , Lei Chen
- & Xili Liu
-
Article
| Open AccessReactivity of Metal-Free and Metal-Associated Amyloid-β with Glycosylated Polyphenols and Their Esterified Derivatives
- Kyle J. Korshavn
- , Milim Jang
- & Mi Hee Lim
-
Article
| Open AccessCross-species conservation of complementary amino acid-ribonucleobase interactions and their potential for ribosome-free encoding
- John G. D. Cannon
- , Rachel M. Sherman
- & Grace A. Newman
-
Article
| Open AccessEnergetics of Endotoxin Recognition in the Toll-Like Receptor 4 Innate Immune Response
- Teresa Paramo
- , Susana M. Tomasio
- & Peter J. Bond
-
Article
| Open AccessDrug-Drug Interaction Potentials of Tyrosine Kinase Inhibitors via Inhibition of UDP-Glucuronosyltransferases
- Nan Zhang
- , Yong Liu
- & Hyunyoung Jeong
-
Article
| Open AccessAPA-style human milk fat analogue from silkworm pupae oil: Enzymatic production and improving storage stability using alkyl caffeates
- Xi Liu
- , Xudong Wang
- & Jun Wang
-
Article
| Open AccessEffects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways
- Carlos Daniel Zappia
- , Gina Granja-Galeano
- & Federico Monczor
-
Article
| Open AccessA small molecule inhibitor for ATPase activity of Hsp70 and Hsc70 enhances the immune response to protein antigens
- Kyung-Hwa Baek
- , Haiying Zhang
- & Injae Shin
-
Article
| Open AccessMating dynamics in a nematode with three sexes and its evolutionary implications
- Jyotiska Chaudhuri
- , Neelanjan Bose
- & Andre Pires-daSilva
-
Article
| Open AccessCollaborative regulation of CO2 transport and fixation during succinate production in Escherichia coli
- Li-Wen Zhu
- , Lei Zhang
- & Ya-Jie Tang
-
Article
| Open AccessStructural Insight into the interaction of Flavonoids with Human Telomeric Sequence
- Arpita Tawani
- & Amit Kumar
-
Article
| Open AccessDiscovery of a Novel Inhibitor of the Protein Tyrosine Phosphatase Shp2
- Chuan Chen
- , Mengmeng Cao
- & Duqiang Luo
-
Article
| Open AccessThe standalone aminopeptidase PepN catalyzes the maturation of blasticidin S from leucylblasticidin S
- Guiyang Yu
- , Li Li
- & Xinyi He
-
Article
| Open AccessDiscovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)
- Kim Huard
- , Janice Brown
- & Derek M. Erion
-
Article
| Open AccessSuppression on plant-parasitic nematodes using a soil fumigation strategy based on ammonium bicarbonate and its effects on the nematode community
- Lanxi Su
- , Yunze Ruan
- & Qirong Shen
-
Article
| Open AccessIn Vivo Linking of Membrane Lipids and the Anion Transporter Band 3 with Thiourea-modified Amphiphilic Lipid Probes
- Akihiro Moriyama
- , Naohiro Katagiri
- & Hideaki Kakeya
-
Article
| Open AccessZeolite Nanoparticles for Selective Sorption of Plasma Proteins
- M. Rahimi
- , E.-P. Ng
- & F. Rezaee
-
Article
| Open AccessQUANTITY: An Isobaric Tag for Quantitative Glycomics
- Shuang Yang
- , Meiyao Wang
- & Shuwei Li
-
Article
| Open AccessMetformin suppressed the proliferation of LoVo cells and induced a time-dependent metabolic and transcriptional alteration
- Jiaojiao He
- , Ke Wang
- & Houkai Li
-
Article
| Open AccessAlkanols inhibit voltage-gated K+ channels via a distinct gating modifying mechanism that prevents gate opening
- Evelyn Martínez-Morales
- , Ivan Kopljar
- & Alain J. Labro
-
Article
| Open AccessEscherichia coli Nissle 1917 enhances bioavailability of serotonin in gut tissues through modulation of synthesis and clearance
- Jonathan Nzakizwanayo
- , Cinzia Dedi
- & Brian V. Jones
-
Article
| Open AccessLovastatin blocks Kv1.3 channel in human T cells: a new mechanism to explain its immunomodulatory properties
- Ning Zhao
- , Qian Dong
- & Yi-Mei Du
-
Article
| Open AccessPericolactines A–C, a New Class of Diterpenoid Alkaloids with Unusual Tetracyclic Skeleton
- Yue-Hua Wu
- , Guo-Dong Chen
- & Hao Gao
-
Article
| Open AccessDelivery of cell-penetrating peptide-peptide nucleic acid conjugates by assembly on an oligonucleotide scaffold
- Xing-Liang Zhao
- , Bi-Cheng Chen
- & Xiao-Ben Pan
-
Article
| Open AccessTandem Spinach Array for mRNA Imaging in Living Bacterial Cells
- Jichuan Zhang
- , Jingyi Fei
- & Taekjip Ha
-
Article
| Open AccessA new application of click chemistry in situ: development of fluorescent probe for specific G-quadruplex topology
- Ming-Hao Hu
- , Xiao Chen
- & Jia-Heng Tan
-
Article
| Open AccessDevelopment of a panel of DNA Aptamers with High Affinity for Pancreatic Ductal Adenocarcinoma
- Carole Champanhac
- , I-Ting Teng
- & Weihong Tan
-
Article
| Open AccessDetermination of Hemicellulose, Cellulose and Lignin in Moso Bamboo by Near Infrared Spectroscopy
- Xiaoli Li
- , Chanjun Sun
- & Yong He
-
Article
| Open AccessLive detection and purification of cells based on the expression of a histone chaperone, HIRA, using a binding peptide
- K. J. Kochurani
- , Annie A. Suganya
- & Tessy T. Maliekal
-
Article
| Open AccessIdentification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins
- An-Guo Wu
- , Vincent Kam-Wai Wong
- & Betty Yuen-Kwan Law
-
Article
| Open AccessSulphur Atoms from Methionines Interacting with Aromatic Residues Are Less Prone to Oxidation
- Juan C. Aledo
- , Francisco R. Cantón
- & Francisco J. Veredas
-
Article
| Open AccessDesign and Synthesis of Near-infrared Fluorescent Probes for Imaging of Biological Nitroxyl
- Yi Tan
- , Ruochuan Liu
- & Hongyan Sun
-
Article
| Open AccessShape-Dependent Skin Penetration of Silver Nanoparticles: Does It Really Matter?
- Yu Kyung Tak
- , Sukdeb Pal
- & Joon Myong Song
-
Article
| Open AccessChelator-Free Labeling of Layered Double Hydroxide Nanoparticles for in Vivo PET Imaging
- Sixiang Shi
- , Brianne C. Fliss
- & Weibo Cai
-
Article
| Open AccessSingle-molecule FRET studies on alpha-synuclein oligomerization of Parkinson’s disease genetically related mutants
- Laura Tosatto
- , Mathew H. Horrocks
- & David Klenerman
-
Article
| Open AccessAn Efficient Site-Specific Method for Irreversible Covalent Labeling of Proteins with a Fluorophore
- Jiaquan Liu
- , Jeungphill Hanne
- & Richard Fishel
-
Article
| Open AccessLipoteichoic acid of Streptococcus oralis Uo5: a novel biochemical structure comprising an unusual phosphorylcholine substitution pattern compared to Streptococcus pneumoniae
- Nicolas Gisch
- , Dominik Schwudke
- & Dalia Denapaite
-
Article
| Open AccessApplication of artificial neural network to investigate the effects of 5-fluorouracil on ribonucleotides and deoxyribonucleotides in HepG2 cells
- Jianru Guo
- , QianQian Chen
- & Wei Zhang
-
Article
| Open AccessA Universal Base in a Specific Role: Tuning up a Thrombin Aptamer with 5-Nitroindole
- Vladimir B. Tsvetkov
- , Anna M. Varizhuk
- & Edward N. Timofeev
Browse broader subjects
Browse narrower subjects
- Biocatalysis
- Biophysical chemistry
- Biosynthesis
- Carbohydrates
- Chemical ecology
- Chemical genetics
- Chemical libraries
- Chemical modification
- Chemical tools
- Cheminformatics
- Combinatorial libraries
- Computational chemistry
- DNA
- Drug delivery
- Enzyme mechanisms
- Enzymes
- Glycobiology
- Glycomics
- Ion channels
- Kinases
- Lipidomics
- Lipids
- Mechanism of action
- Membranes
- Metabolic pathways
- Metabolomics
- Metals
- Natural products
- Networks and systems biology
- Nucleic acids
- Peptides
- Pharmacology
- Post-translational modifications
- Proteases
- Protein design
- Protein folding
- Proteins
- Proteomics
- RNA
- Screening
- Small molecules
- Synthetic biology
- Target identification
- Target validation
- Transporters