Cell biology articles from across Nature Portfolio

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools and examines all cell types, from unicellular organisms such as protozoa to the specialised cells that consitutute multicellular organisms.

Featured

News & Views | 31 May 2023

A structural model of the core of cilia

Nature
News & Views | 29 May 2023

Deciphering subcellular organization with multiplexed imaging and deep learning

Nature Methods, 1-2
News & Views | 29 May 2023

Flipping the polarity switch
- Daniel W. Bak
Nature Chemical Biology, 1-2

Latest Research and Reviews

Reviews
01 June 2023 | Open Access

Nutrient sensors and their crosstalk
- Yulseung Sung
- , Ya Chun Yu
- & Jung Min Han
Experimental & Molecular Medicine, 1-14
Reviews
01 June 2023 | Open Access

Functional roles of sphingolipids in immunity and their implication in disease
- Mingyu Lee
- , Suh Yeon Lee
- & Yoe-Sik Bae
Experimental & Molecular Medicine, 1-21
Research
01 June 2023 | Open Access

TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1
- Xiaowei Fei
- , Ya-nan Dou
- & Zhou Fei
Experimental & Molecular Medicine, 1-15
Research
01 June 2023 | Open Access

SIRT1 ubiquitination is regulated by opposing activities of APC/C-Cdh1 and AROS during stress-induced premature senescence
- Sang Hyup Lee
- , Ji-Hye Yang
- & Eun-Joo Kim
Experimental & Molecular Medicine, 1-15
Reviews | 31 May 2023

Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles

Oligodendrocytes secrete extracellular vesicles, which deliver cargo to axons where they regulate key cellular processes. In this Review, Krämer-Albers and Werner discuss the mechanisms by which extracellular vesicles promote neuronal health and their potential to be utilized therapeutically.
- Eva-Maria Krämer-Albers
- & Hauke B. Werner
Nature Reviews Neuroscience, 1-13
Research
31 May 2023 | Open Access

Axonemal structures reveal mechanoregulatory and disease mechanisms

Detailed atomic models of axonemes from algal flagella and human respiratory cilia, which are hair-like protrusions from cells that enable motility and clear mucus from human airways, could provide insights into how they function.
- Travis Walton
- , Miao Gui
- & Alan Brown
Nature, 1-9

All Research & Reviews

News and Comment

Research Highlights | 31 May 2023

Dysfunctional UCH-L1 inhibits proteostasis
- Monica Wang
Nature Reviews Nephrology, 1
News & Views | 31 May 2023

A structural model of the core of cilia

Axonemes are molecular machines that enable the movement of cilia, the hair-like structures found on the surface of some cells. Atomic models of axonemes from the flagella of green algae and from the cilia of human respiratory-tract cells reveal how the axoneme enables the cilia to move, and explain the effects of genetic mutations that cause human ciliary disease.

Nature
Comments & Opinion | 30 May 2023

Cullin 4B-RING E3 ligase complex in immune cell differentiation and function
- Yu Song
- , Shiqi Jin
- & Yaoqin Gong
Cellular & Molecular Immunology, 1-3
News & Views | 29 May 2023

Deciphering subcellular organization with multiplexed imaging and deep learning

Our study introduces conditional autoencoder for multiplexed pixel analysis (CAMPA), a deep-learning framework that uses highly multiplexed imaging to identify consistent subcellular landmarks across heterogeneous cell populations and experimental perturbations. Generating interpretable cellular phenotypes revealed links between subcellular organization and perturbations of RNA production, RNA processing and cell size.

Nature Methods, 1-2
News & Views | 29 May 2023

Flipping the polarity switch

A new platform for screening nucleophilic-fragment-based covalent ligands enables the identification and targeting of ligandable sulfenic acid sites, setting the stage for exploration of nucleophile-directed probe and drug development.
- Daniel W. Bak
Nature Chemical Biology, 1-2
Research Highlights | 26 May 2023

Studying lysosomal function and dysfunction using LysoIP

In this Tools of the Trade article, Nouf Laqtom (at the Abu-Remaileh lab) describes the LysoIP system used to tag and isolate lysosomes for multi-omic approaches and to determine their composition under physiological and pathological states.
- Nouf N. Laqtom
Nature Reviews Molecular Cell Biology, 1

All News & Comment

Cell biology articles from across Nature Portfolio

Featured

A structural model of the core of cilia

Deciphering subcellular organization with multiplexed imaging and deep learning

Flipping the polarity switch

Latest Research and Reviews

Nutrient sensors and their crosstalk

Functional roles of sphingolipids in immunity and their implication in disease

TRIM22 promotes the proliferation of glioblastoma cells by activating MAPK signaling and accelerating the degradation of Raf-1

SIRT1 ubiquitination is regulated by opposing activities of APC/C-Cdh1 and AROS during stress-induced premature senescence

Mechanisms of axonal support by oligodendrocyte-derived extracellular vesicles

Axonemal structures reveal mechanoregulatory and disease mechanisms

News and Comment

Dysfunctional UCH-L1 inhibits proteostasis

A structural model of the core of cilia

Cullin 4B-RING E3 ligase complex in immune cell differentiation and function

Deciphering subcellular organization with multiplexed imaging and deep learning

Flipping the polarity switch

Studying lysosomal function and dysfunction using LysoIP

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Cell biology articles from across Nature Portfolio

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