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Tolerability and tropism of recombinant adeno-associated virus vectors in the African green monkey (Chlorocebus sabaeus) anterior chamber
- Kristina J. Chern
- , Kimicia Z. Issac
- & Daniel M. Lipinski
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Article |
Loss of RAGE prevents chronic intermittent hypoxia-induced nonalcoholic fatty liver disease via blockade of NF-кB pathway
- Haoqu Tan
- , Jinfang Hu
- & Wei Bai
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Review Article |
Cerebral organoids as an in vitro model to study autism spectrum disorders
- Alexa Rabeling
- & Mubeen Goolam
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Article |
Effects of intracardiac delivery of aldehyde dehydrogenase 2 gene in myocardial salvage
- Guodong Pan
- , Bipradas Roy
- & Suresh Selvaraj Palaniyandi
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Article |
Exosomal PD-L1 confers chemoresistance and promotes tumorigenic properties in esophageal cancer cells via upregulating STAT3/miR-21
- Haojie Wang
- , Yijun Qi
- & Gaofeng Liang
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Article
| Open AccessDevelopment and biological characterization of a clinical gene transfer vector for the treatment of MAK-associated retinitis pigmentosa
- Budd A. Tucker
- , Erin R. Burnight
- & Edwin M. Stone
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Article |
XIAP gene therapy effects on retinal ganglion cell structure and function in a mouse model of glaucoma
- Shagana Visuvanathan
- , Adam N. Baker
- & Catherine Tsilfidis
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Review Article |
Intracellular trafficking of adeno-associated virus (AAV) vectors: challenges and future directions
- Jalish M. Riyad
- & Thomas Weber
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Review Article
| Open AccessImplications of hematopoietic stem cells heterogeneity for gene therapies
- Jeremy Epah
- & Richard Schäfer
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Article |
Restored microRNA-519a enhances the radiosensitivity of non-small cell lung cancer via suppressing EphA2
- Shulei Gong
- , Yu Li
- & Wanfu Men
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Article |
Promoting role of circ-Jarid2/miR-129-5p/Celf1 axis in cardiac hypertrophy
- Yan Fang
- , Yu Tao
- & Hengli Lai
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Article |
Knockdown of LINC00467 contributed to Axitinib sensitivity in hepatocellular carcinoma through miR-509-3p/PDGFRA axis
- Wei Li
- , Yufeng He
- & Po Yang
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Article |
miR-19a/19b improves the therapeutic potential of mesenchymal stem cells in a mouse model of myocardial infarction
- Chengbo Chen
- , Tianbao Chen
- & Youbang Xu
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Article |
MicroRNA-204 silencing relieves pain of cervical spondylotic radiculopathy by targeting GDNF
- Wen-Sheng Shen
- , Cun-Feng Li
- & Lu-Ping Pan
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Article |
RETRACTED ARTICLE: Long noncoding RNA RBMS3-AS3 acts as a microRNA-4534 sponge to inhibit the progression of prostate cancer by upregulating VASH1
- Zhenming Jiang
- , Yuxi Zhang
- & Dong Chen
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Article |
Safety profiling of genetically engineered Pim-1 kinase overexpression for oncogenicity risk in human c-kit+ cardiac interstitial cells
- Kathleen Broughton
- , Kelli Korski
- & Mark A. Sussman
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Article |
Polarized AAVR expression determines infectivity by AAV gene therapy vectors
- Bradley A. Hamilton
- , Xiaopeng Li
- & Joseph Zabner
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Article |
Inhibition of microRNA-495 suppresses chondrocyte apoptosis through activation of the NF-κB signaling pathway by regulating CCL4 in osteoarthritis
- Da-Wei Yang
- , Gui-Bin Qian
- & Kun-Zheng Wang
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Article |
ILK promotes survival and self-renewal of hypoxic MSCs via the activation of lncTCF7-Wnt pathway induced by IL-6/STAT3 signaling
- Qing Mao
- , Xiu-Lin Liang
- & Yong-Xiang Lu
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Brief Communication |
Downreguation of FoxM1 by miR-214 inhibits proliferation and migration in hepatocellular carcinoma
- Chuan Tian
- , Haixia Wu
- & Wei Song
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Brief Communication |
Additive effects of the combined expression of soluble forms of GAS1 and PTEN inhibiting glioblastoma growth
- Laura Sánchez-Hernández
- , Justino Hernández-Soto
- & José Segovia
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Article |
LncRNA FTX sponges miR-215 and inhibits phosphorylation of vimentin for promoting colorectal cancer progression
- Yi Yang
- , Jinpei Zhang
- & Tao Wu
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Short Communication |
In situ regeneration of retinal pigment epithelium by gene transfer of E2F2: a potential strategy for treatment of macular degenerations
- D Kampik
- , M Basche
- & R R Ali
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Original Article |
Targeting the CXCR4/CXCL12 axis in treating epithelial ovarian cancer
- T L Mao
- , K F Fan
- & C L Liu
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Original Article |
SOST silencing promotes proliferation and invasion and reduces apoptosis of retinoblastoma cells by activating Wnt/β-catenin signaling pathway
- T Wu
- , L-N Wang
- & F-Y Sun
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Review |
How the discovery of ISS-N1 led to the first medical therapy for spinal muscular atrophy
- N N Singh
- , M D Howell
- & R N Singh
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Original Article |
INSR gene polymorphisms correlate with sensitivity to platinum-based chemotherapy and prognosis in patients with epithelial ovarian cancer
- J-L Hu
- , X-L Hu
- & S-D Cang
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Review |
Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy
- L Jiang
- , P Vader
- & R M Schiffelers
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Original Article |
The antitumor efficacy of anti-p21Ras scFv mediated by the dual-promoter-regulated recombinant adenovirus KGHV300
- X Y Pan
- , X J Liu
- & J L Yang
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Original Article |
Immune effect and safety evaluation of vaccine prepared by dendritic cells modified by rAAV-carrying BCSG1 gene
- W-H Wang
- , C-H Zhou
- & W Zhang
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Comment |
Novel approaches toward managing the micromanagers: ‘non-toxic’ but effective
- T G H Diekwisch
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Original Article |
Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies
- K Roellecke
- , E L Virts
- & H Hanenberg
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Original Article |
β1-Na+,K+-ATPase gene therapy upregulates tight junctions to rescue lipopolysaccharide-induced acute lung injury
- X Lin
- , M Barravecchia
- & D A Dean
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Original Article |
HSV vector-mediated GAD67 suppresses neuropathic pain induced by perineural HIV gp120 in rats through inhibition of ROS and Wnt5a
- H Kanda
- , M Kanao
- & S Hao
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Short Communication |
Transient suppression of hepatocellular replication in the mouse liver following transduction with recombinant adeno-associated virus
- A P Dane
- , S C Cunningham
- & I E Alexander
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Short Communication |
miR-16 rescues F508del-CFTR function in native cystic fibrosis epithelial cells
- P Kumar
- , S Bhattacharyya
- & R Biswas
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Original Article |
Enhanced T-cell activation and differentiation in lymphocytes from transgenic mice expressing ubiquitination-resistant 2KR LAT molecules
- A B Rodriguez-Peña
- , J Gomez-Rodriguez
- & L Balagopalan
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Original Article |
Gene electrotransfer of plasmid AMEP, an integrin-targeted therapy, has antitumor and antiangiogenic action in murine B16 melanoma
- M Bosnjak
- , T Dolinsek
- & G Sersa
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Original Article |
Ameliorating pathogenesis by removing an exon containing a missense mutation: a potential exon-skipping therapy for laminopathies
- J Scharner
- , N Figeac
- & P S Zammit
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Original Article |
The role of transduced bone marrow cells overexpressing BMP-2 in healing critical-sized defects in a mouse femur
- M Pensak
- , S Hong
- & J R Lieberman
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Original Article |
Shedding of clinical-grade lentiviral vectors is not detected in a gene therapy setting
- M Cesani
- , T Plati
- & A Biffi
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Original Article |
SPARC (secreted protein acidic and rich in cysteine) knockdown protects mice from acute liver injury by reducing vascular endothelial cell damage
- E Peixoto
- , C Atorrasagasti
- & G Mazzolini
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Original Article |
Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice
- V Vauthier
- , T D Swartz
- & J Dam
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Original Article |
Deletion of CXCR4 in cardiomyocytes exacerbates cardiac dysfunction following isoproterenol administration
- E R Wang
- , A A Jarrah
- & S T Tarzami
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Original Article |
Sonic hedgehog gene therapy increases the ability of the dystrophic skeletal muscle to regenerate after injury
- A Piccioni
- , E Gaetani
- & R Pola
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Original Article |
Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway
- C-H Lee
- , S-T Lin
- & W-K Wang
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