Cancer prevention articles within Nature

Featured

  • Article |

    The growth of colorectal cancer is reduced by ketogenic diet consumption, the properties of which are mediated by the ketone body β-hydroxybutyrate.

    • Oxana Dmitrieva-Posocco
    • , Andrea C. Wong
    •  & Maayan Levy

  • Article |

    A mouse model of papillomavirus infection reveals that skin colonization with commensal papillomaviruses protects the immunocompetent host against chemical- and UV-induced skin cancer through CD8+ T cell immunity.

    • John D. Strickley
    • , Jonathan L. Messerschmidt
    •  & Shadmehr Demehri

  • Article |

    Recent analyses have suggested that the intrinsic behaviour of tissue stem cells may be responsible for malignant transformation and cancer progression, raising questions regarding the influence of extrinsic factors on tumourigenesis; here, both data-driven and model-driven evidence show that such intrinsic risk factors contribute only marginally to cancer development, indicating that cancer risk is heavily influenced by extrinsic factors.

    • Song Wu
    • , Scott Powers
    •  & Yusuf A. Hannun

  • Outlook |

    Carcinogens are all around us, so scientists are broadening their ideas of environmental risk.

    • Rebecca Kessler

  • Outlook |

    Much of the world is ill-equipped to cope with its rising cancer burden and are pushing prevention and screening.

    • Eric Bender

  • Letter |

    Individuals with the red hair/fair skin phenotype usually carry a polymorphism in the gene encoding the melanocortin 1 receptor (Mc1r) that results in the production of pigment containing a high pheomelanin-to-eumelanin ratio; here it is shown in a mouse model that inactivation of Mc1r promotes melanoma formation in the presence of the Braf oncogene, thus suggesting that pheomelanin synthesis is carcinogenic by an ultraviolet-radiation-independent mechanism.

    • Devarati Mitra
    • , Xi Luo
    •  & David E. Fisher

  • Outlook |

    Physical activity has numerous proven benefits, and its long-contested ability to keep cancer at bay is now being put to the test.

    • Julie Corliss

  • Outlook |

    Barbara Dunn is a programme director in the Division of Cancer Prevention at the National Cancer Institute (NCI). She tells Nature Outlook about the challenges of stopping the disease before it starts.

    • Barbara Dunn

  • News & Views |

    Cyclin D1 is one of the drivers of the cell cycle, and its deregulation may promote the development of tumours. Surprisingly, this protein also mediates the repair of damaged DNA, a mechanism that commonly prevents cancer. See Letter p.230

    • Jiri Bartek
    •  & Jiri Lukas

  • Outlook |

    Successful prevention requires attacking the causes, says Stephen S. Hecht—and the main target remains tobacco.

    • Stephen S. Hecht

  • Outlook |

    Despite our relative wealth of knowledge about the causes of cancer, the disease persists — and the burden is worsening. Prevention demands political will, ample funding and a change in mindset.

    • Tiffany O'Callaghan

  • News & Views |

    Prognosis for patients with pancreatic cancer is bleak, often owing to late diagnosis. The estimate that at least 15 years pass from tumour initiation to malignancy offers hope for early detection and prevention. See Letters p.1109 & p.1114

    • E. Georg Luebeck

Browse broader subjects

Browse Cancer prevention across other nature.com journals