Targeted bone remodelling articles from across Nature Portfolio
Targeted bone remodelling is bone remodelling in response to the mechanical microdamage that occurs constantly. The damaged bone is removed through targeted bone breakdown (resorption) by specialised cells called osteoclasts and new bone is formed by the action of cells called osteoblasts.
Latest Research and Reviews
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Denervation during mandibular distraction osteogenesis results in impaired bone formation
Scientific Reports 13, 2097 -
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Regulation of bone homeostasis by MERTK and TYRO3
Nature Communications 13, 7689
A novel Hoxd13 mutation causes synpolydactyly and promotes osteoclast differentiation by regulating pSmad5/p65/c-Fos/Rank axis
Denervation during mandibular distraction osteogenesis results in impaired bone formation
Resveratrol protects osteocytes against oxidative stress in ovariectomized rats through AMPK/JNK1-dependent pathway leading to promotion of autophagy and inhibition of apoptosis
Proline-rich protein from S. mutans can perform a competitive mineralization function to enhance bacterial adhesion to teeth
The release of osteoclast-stimulating factors on supraphysiological loading by osteoprogenitors coincides with expression of genes associated with inflammation and cytoskeletal arrangement
Regulation of bone homeostasis by MERTK and TYRO3