Body mass index articles within Nature Communications

Featured

• Article
  02 February 2016 | Open Access

  GWAS of 89,283 individuals identifies genetic variants associated with self-reporting of being a morning person

  Circadian rhythms and related behaviours vary across individuals. Here, a large genome-wide association study reveals common single nucleotide variants influencing whether an individual reports as being a ‘morning person’ by identifying 15 significant loci, including 7 near known circadian genes.

  • Youna Hu
  • , Alena Shmygelska
  •  & David A. Hinds

• Article
  20 November 2015 | Open Access

  Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans

  Brown adipose tissue (BAT) thermogenesis is an important determinant of organismal energy expenditure in mammals. Here, Whittle et al. report that the protein sLR11 is a negative regulator of BAT activity in mice, repressing thermogenesis by inhibiting BMP/Smad signalling in brown adipocytes.

  • Andrew J. Whittle
  • , Meizi Jiang
  •  & Hideaki Bujo