Biosensors are devices used to detect the presence or concentration of a biological analyte, such as a biomolecule, a biological structure or a microorganism. Biosensors consist of three parts: a component that recognizes the analyte and produces a signal, a signal transducer, and a reader device.

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News and Comment

  • News and Views |

    The tumour microenvironment has a specific enzymatic fingerprint, which provides opportunities for cancer therapy. Now, two studies show how this unique chemical environment can be used to produce reporter molecules or nanoclusters within the tumour that can subsequently be identified in urine or breath, enabling cancer detection and monitoring.

    • Alexander N. Zelikin
    Nature Chemistry 12, 11-12
  • Research Highlights |

    Metabolic disorders cause anomalous productions of chemicals in our bodies that may lead to serious diseases. Functionalized tattoo inks can be effectively use to constantly detect metabolites.

    • Gabriella Graziano
  • News and Views |

    An electrical biosensor that relies on the binding of target nucleic acid sequences to Cas9 immobilized on a graphene field-effect transistor enables the rapid detection of mutations in purified samples without the need for nucleic acid amplification.

    • Richard Bruch
    • , Gerald A. Urban
    •  & Can Dincer