Biophotonics articles from across Nature Portfolio

The authors use deep learning to detect and segment unlabeled and unaltered protein aggregates in living cells from transmitted-light images. The method provides a way to quantitatively study protein aggregation dynamics in a simple, fast and accurate way.

Molecular vibrations serve as valuable signatures for the constituent elements and bonding in compounds. Here, using Surface-Enhanced Infrared Absorption spectroscopy, the authors study refractive index dependent vibrations of surface phonon polaritons and surface plasmon platform, targeting dynamic biomonitoring.

Deep imaging in complex scattering media is hindered by multiple light scattering. Here, the authors proposed a method to trace multiple scattering trajectories in situ using a recorded reflection matrix and achieved enhanced imaging depth by converting these multiple scattering to signal waves.

Three-dimensional photoacoustic tomography synchronized with an electrocardiogram provides highly resolved images of a beating heart with optical absorption contrast and enables investigation of cardiovascular diseases in animal models.