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| Open AccessA pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration
- Anna L. Beukenhorst
- , Jacopo Frallicciardi
- & Jaap Goudsmit
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| Open AccessEfficacy evaluation of a bivalent subunit vaccine against classical swine fever virus and porcine circovirus type 2
- Yu-San Chen
- , Chang-Ye Lee
- & Charles Chen
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| Open AccessLong-lasting blocking of interoceptive effects of cocaine by a highly efficient cocaine hydrolase in rats
- Huimei Wei
- , Johnathan E. LeSaint
- & Fang Zheng
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| Open AccessComprehensive modeling of cell culture profile using Raman spectroscopy and machine learning
- Hiroki Tanemura
- , Ryunosuke Kitamura
- & Koichi Nonaka
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| Open AccessHigh-throughput analysis system of interaction kinetics for data-driven antibody design
- Ryo Matsunaga
- , Kan Ujiie
- & Kouhei Tsumoto
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| Open AccessAn in vitro model of the macrophage-endothelial interface to characterize CAR T-cell induced cytokine storm
- Robert S. Rosen
- , Jason H. Yang
- & Martin L. Yarmush
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| Open AccessDiagnostic utility of N-terminal TMPP labels for unambiguous identification of clipped sites in therapeutic proteins
- Harsha P. Gunawardena
- , Meth M. Jayatilake
- & Hirsh Nanda
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| Open AccessInsights into next generation sequencing guided antibody selection strategies
- M. Frank Erasmus
- , Fortunato Ferrara
- & Andrew R. M. Bradbury
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| Open AccessMulti-structural molecular docking (MOD) combined with molecular dynamics reveal the structural requirements of designing broad-spectrum inhibitors of SARS-CoV-2 entry to host cells
- Anqi Da
- , Meritxell Wu-Lu
- & Kourosh H. Ebrahimi
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| Open AccessAssessment of safety and intranasal neutralizing antibodies of HPMC-based human anti-SARS-CoV-2 IgG1 nasal spray in healthy volunteers
- Thanarath Imsuwansri
- , Thitinan Jongthitinon
- & Trairak Pisitkun
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| Open AccessBivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells
- Masaki Inoue
- , Yuta Tsuji
- & Shin-ichi Tsunoda
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| Open AccessDiscovery and multimerization of cross-reactive single-domain antibodies against SARS-like viruses to enhance potency and address emerging SARS-CoV-2 variants
- Scott A. Hollingsworth
- , Cameron L. Noland
- & Kalyan Pande
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| Open AccessPreclinical immunological characterization of rademikibart (CBP-201), a next-generation human monoclonal antibody targeting IL-4Rα, for the treatment of Th2 inflammatory diseases
- Limin Zhang
- , Ying Ding
- & Xin Yang
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| Open AccessIn major joint diseases the human synovium retains its potential to form repair cartilage
- Ernst B. Hunziker
- , Nahoko Shintani
- & Marius J. B. Keel
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| Open AccessCross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy
- Christoffer V. Sørensen
- , Line Ledsgaard
- & Andreas H. Laustsen
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| Open AccessFc-competent multispecific PDL-1/TIGIT/LAG-3 antibodies potentiate superior anti-tumor T cell response
- Riyao Yang
- , Su Huang
- & Yue Liu
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| Open AccessTozorakimab (MEDI3506): an anti-IL-33 antibody that inhibits IL-33 signalling via ST2 and RAGE/EGFR to reduce inflammation and epithelial dysfunction
- Elizabeth England
- , D. Gareth Rees
- & E. Suzanne Cohen
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Article
| Open AccessDARPins bind their cytosolic targets after having been translocated through the protective antigen pore of anthrax toxin
- Lukas Becker
- & Andreas Plückthun
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| Open AccessScalable continuous-flow electroporation platform enabling T cell transfection for cellular therapy manufacturing
- Jacob A. VanderBurgh
- , Thomas N. Corso
- & Harold G. Craighead
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Article
| Open AccessResults of a phase Ib study of SB-121, an investigational probiotic formulation, a randomized controlled trial in participants with autism spectrum disorder
- Lauren M. Schmitt
- , Elizabeth G. Smith
- & Craig A. Erickson
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| Open AccessThe IgV domain of the poliovirus receptor alone is immunosuppressive and binds to its receptors with comparable affinity
- Shrayasee Saha
- , Amanda Sparkes
- & Jean Gariépy
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| Open AccessCharacterization of human anti-EpCAM antibodies for developing an antibody–drug conjugate
- Hiroyuki Satofuka
- , Yayan Wang
- & Yasuhiro Kazuki
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| Open AccessDevelopment of an inhibiting antibody against equine interleukin 5 to treat insect bite hypersensitivity of horses
- Nora Langreder
- , Dorina Schäckermann
- & Michael Hust
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| Open AccessNon-optimal ambient temperatures aggravate insecticide toxicity and affect honey bees Apis mellifera L. gene regulation
- Mohamed Alburaki
- , Shayne Madella
- & Steven C. Cook
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| Open AccessOptimizing variant-specific therapeutic SARS-CoV-2 decoys using deep-learning-guided molecular dynamics simulations
- Katharina Köchl
- , Tobias Schopper
- & Christian C. Gruber
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| Open AccessNanobodies targeting ABCC3 for immunotargeted applications in glioblastoma
- Eduardo Ruiz-López
- , Ivana Jovčevska
- & Alberto J. Schuhmacher
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| Open AccessSpectroscopic characterization and assessment of microbiological potential of 1,3,4-thiadiazole derivative showing ESIPT dual fluorescence enhanced by aggregation effects
- Iwona Budziak-Wieczorek
- , Lidia Ślusarczyk
- & Arkadiusz Matwijczuk
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| Open AccessCharacterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models
- Stephane Illiano
- , Bruno Poirier
- & Philip Janiak
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| Open AccessPlant-produced recombinant cytokines IL-37b and IL-38 modulate inflammatory response from stimulated human PBMCs
- Igor Kolotilin
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| Open AccessThe ischaemic preconditioning paradox and its implications for islet isolation from heart-beating and non heart-beating donors
- Daniel Brandhorst
- , Heide Brandhorst
- & Paul R. V. Johnson
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Article
| Open AccessAntibody-dependent cellular cytotoxicity-null effector developed using mammalian and plant GlycoDelete platform
- Cho Eun Kang
- , Seungeun Lee
- & Woo Taek Kim
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| Open AccessA novel anti-TNF-α drug ozoralizumab rapidly distributes to inflamed joint tissues in a mouse model of collagen induced arthritis
- Shohei Oyama
- , Kosuke Ebina
- & Ken Nakata
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| Open AccessIsolation and characterization of phage display-derived scFv antibodies against human parechovirus 1 VP0 protein
- Eero Hietanen
- , Lav Tripathi
- & Petri Susi
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| Open AccessDry preserved multilayered fibroblast cell sheets are a new manageable tool for regenerative medicine to promote wound healing
- Yutaro Matsuno
- , Masashi Yanagihara
- & Kimikazu Hamano
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| Open AccessDevelopment and characterization of a camelid derived antibody targeting a linear epitope in the hinge domain of human PCSK9 protein
- Xinyang Li
- , Jun Hong
- & Naibo Yang
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Article
| Open AccessLong-term posterolateral spinal fusion in rabbits induced by rhBMP6 applied in autologous blood coagulum with synthetic ceramics
- Nikola Stokovic
- , Natalia Ivanjko
- & Slobodan Vukicevic
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| Open AccessCrystal structure of ultra-humanized anti-pTau Fab reveals how germline substitutions humanize CDRs without loss of binding’
- Alette R. Brinth
- , Kristine Svenson
- & Matthew Lambert
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| Open AccessIn-situ scalable manufacturing of Epstein–Barr virus-specific T-cells using bioreactor with an expandable culture area (BECA)
- Sixun Chen
- , Ahmad Amirul Bin Abdul Rahim
- & Dan Liu
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| Open AccessEffects of Imipenem-containing Niosome nanoparticles against high prevalence methicillin-resistant Staphylococcus Epidermidis biofilm formed
- Tohid Piri-Gharaghie
- , Neda Jegargoshe-Shirin
- & Sadegh Fatehi-Ghahfarokhi
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| Open AccessIn vivo imaging with two-photon microscopy to assess the tumor-selective binding of an anti-CD137 switch antibody
- Chisato Kaneko
- , Haruka Tsutsui
- & Masaru Ishii
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| Open AccessAdvances in purification of SARS-CoV-2 spike ectodomain protein using high-throughput screening and non-affinity methods
- Nicole Cibelli
- , Gabriel Arias
- & Daniel B. Gowetski
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| Open AccessFirst-in-class trispecific VHH-Fc based antibody with potent prophylactic and therapeutic efficacy against SARS-CoV-2 and variants
- Allison Titong
- , Sachith Gallolu Kankanamalage
- & Yue Liu
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| Open AccessTransiently expressed CRISPR/Cas9 induces wild-type dystrophin in vitro in DMD patient myoblasts carrying duplications
- Veronica Pini
- , Virginie Mariot
- & Francesco Muntoni
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Article
| Open AccessHuman infrapatellar fat pad mesenchymal stem cells show immunomodulatory exosomal signatures
- Dimitrios Kouroupis
- , Lee D. Kaplan
- & Thomas M. Best
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| Open AccessA cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors
- Julie K. Fierle
- , Johan Abram-Saliba
- & Steven M. Dunn
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| Open AccessExtension of human GCSF serum half-life by the fusion of albumin binding domain
- Fatemeh Yadavar Nikravesh
- , Samira Shirkhani
- & Soroush Sardari
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Article
| Open AccessInhibitory properties of crude microalgal extracts on the in vitro replication of cyprinid herpesvirus 3
- Stefanie Fritzsche
- , Patrik Blenk
- & Anna Maria Becker
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Article
| Open AccessTwo novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity
- Deyong Song
- , Xiu Liu
- & Changlin Dou
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| Open AccessMeasurements of spontaneous CFTR-mediated ion transport without acute channel activation in airway epithelial cultures after modulator exposure
- Heidi J. Nick
- , Pamela L. Zeitlin
- & Preston E. Bratcher
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