Biological sciences

Definition

Biological sciences encompasses all the divisions of natural sciences examining various aspects of vital processes. The concept includes anatomy, physiology, cell biology, biochemistry and biophysics, and covers all organisms from microorganisms, animals to plants.

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Latest Research and Reviews

  • Research |

    The development of selective ubiquitin-specific protease-7 (USP7) inhibitors GNE-6640 and GNE-6776, which induce tumour cell death and reveal differential kinetics of Lys-48 and Lys-63-linked ubiquitin chain depolymerization by USP7.

    • Lorna Kategaya
    • , Paola Di Lello
    • , Lionel Roug√©
    • , Richard Pastor
    • , Kevin R. Clark
    • , Jason Drummond
    • , Tracy Kleinheinz
    • , Eva Lin
    • , John-Paul Upton
    • , Sumit Prakash
    • , Johanna Heideker
    • , Mark McCleland
    • , Maria Stella Ritorto
    • , Dario R. Alessi
    • , Matthias Trost
    • , Travis W. Bainbridge
    • , Michael C. M. Kwok
    • , Taylur P. Ma
    • , Zachary Stiffler
    • , Bradley Brasher
    • , Yinyan Tang
    • , Priyadarshini Jaishankar
    • , Brian R. Hearn
    • , Adam R. Renslo
    • , Michelle R. Arkin
    • , Frederick Cohen
    • , Kebing Yu
    • , Frank Peale
    • , Florian Gnad
    • , Matthew T. Chang
    • , Christiaan Klijn
    • , Elizabeth Blackwood
    • , Scott E. Martin
    • , William F. Forrest
    • , James A. Ernst
    • , Chudi Ndubaku
    • , Xiaojing Wang
    • , Maureen H. Beresini
    • , Vickie Tsui
    • , Carsten Schwerdtfeger
    • , Robert A. Blake
    • , Jeremy Murray
    • , Till Maurer
    •  & Ingrid E. Wertz
  • Research |

    Using data from sixty thousand generations of the E. coli long-term evolution experiment, the authors shed new light on the processes that govern molecular evolution.

    • Benjamin H. Good
    • , Michael J. McDonald
    • , Jeffrey E. Barrick
    • , Richard E. Lenski
    •  & Michael M. Desai
  • Research |

    Metabolic flux analysis in mice reveals that lactate often acts as the primary carbon source for the tricarboxylic acid cycle both in normal tissues and in tumour microenvironments.

    • Sheng Hui
    • , Jonathan M. Ghergurovich
    • , Raphael J. Morscher
    • , Cholsoon Jang
    • , Xin Teng
    • , Wenyun Lu
    • , Lourdes A. Esparza
    • , Tannishtha Reya
    • , Le Zhan
    • , Jessie Yanxiang Guo
    • , Eileen White
    •  & Joshua D. Rabinowitz
  • Research |

    After acute inflammation, epithelial stem cells retain a memory that accelerates restoration of the skin barrier during subsequent tissue damage, and this enhancement is dependent on the AIM2 inflammasome and its downstream effectors.

    • Shruti Naik
    • , Samantha B. Larsen
    • , Nicholas C. Gomez
    • , Kirill Alaverdyan
    • , Ataman Sendoel
    • , Shaopeng Yuan
    • , Lisa Polak
    • , Anita Kulukian
    • , Sophia Chai
    •  & Elaine Fuchs
  • Research |

    Disordered nanoscale striations on petals, tepals and bracts have evolved multiple times among flowering plants and provide a salient visual signal to foraging bumblebees (Bombus terrestris).

    • Edwige Moyroud
    • , Tobias Wenzel
    • , Rox Middleton
    • , Paula J. Rudall
    • , Hannah Banks
    • , Alison Reed
    • , Greg Mellers
    • , Patrick Killoran
    • , M. Murphy Westwood
    • , Ullrich Steiner
    • , Silvia Vignolini
    •  & Beverley J. Glover
  • Research |

    Interactions with male and female intruders activated overlapping neuronal populations in the ventromedial hypothalamus of inexperienced adult male mice, and these ensembles gradually separated as the mice acquired social and sexual experience with conspecifics.

    • Ryan Remedios
    • , Ann Kennedy
    • , Moriel Zelikowsky
    • , Benjamin F. Grewe
    • , Mark J. Schnitzer
    •  & David J. Anderson
    Nature 550, 388–392

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