Bacteriophages

Bacteriophages are infectious agents that comprise viruses that infect bacteria. Bacteriophages are widespread, abundant and very diverse.

Latest Research and Reviews

News and Comment

  • News and Views |

    Two recent studies reveal a virus anti-defence strategy whereby large, ‘jumbo’ phages protect themselves from both restriction endonucleases and DNA-targeting CRISPR–Cas systems, but not from RNA-targeting ones, by encapsulating the phage genome inside the cell in a ‘nucleus’-like shell that is impenetrable for CRISPR effectors.

    • Eugene V. Koonin
    •  & Mart Krupovic
  • News and Views |

    Culture-independent methods capable of connecting bacteriophages (phages) to their target host bacteria will help define the roles of phages in host-associated microbiotas. A recent study used fluorescently dyed intestinal phages to identify novel phage–bacterial interactions from the human intestine.

    • Cydney N. Johnson
    •  & Breck A. Duerkop
    Nature Microbiology 4, 2033-2034
  • Research Highlights |

    A study reports the generation of synthetic ‘phagebodies’ with a broadened host range that were able to target naturally occurring phage-resistant bacterial mutants.

    • Andrea Du Toit