Bacterial systems biology

Bacterial systems biology is the scientific study of the functions and properties of bacteria in an integrative, systematic way, based on the analysis and modelling of large data sets. Systems biology is, for example, used to build networks of bacterial metabolism.

Latest Research and Reviews

News and Comment

  • News & Views |

    Bacteria use CRISPR–Cas systems as adaptive defence weapons against attacking phages. A new study shows that under severe stress conditions, Serratia turn off their CRISPR immune system to increase the uptake of potentially beneficial plasmids.

    • Beat Christen
    Nature Microbiology 6, 149-150
  • Editorial |

    Microbiome research has attracted considerable attention, partially because of the potential to manipulate the microbiome for human health. To fulfil this promise, tractable methods and cautious interpretation of results are needed.

  • News & Views |

    It has been assumed that bacteria adapt to nutrient limitation by adjusting the number of ribosomes, no matter what they are being starved for. Instead, two recent studies show that Escherichia coli uses different approaches depending on whether its growth is limited by the availability of carbon, nitrogen or phosphate.

    • Katarzyna Potrykus
    •  & Michael Cashel
    Nature Microbiology 3, 862-863