Bacterial infection

Definition

Bacterial infection refers to the invasion of a host's tissue by a pathogenic bacteria.

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Latest Research and Reviews

  • Research |

    Pseudomonas aeruginosa quorum-sensing signal N-(3-oxo-dodecanoyl) homoserine lactone alters host cell membranes and induces host cell death via ligand-independent immune receptor ligation.

    • Dingka Song
    • , Junchen Meng
    • , Jie Cheng
    • , Zheng Fan
    • , Pengyu Chen
    • , Hefei Ruan
    • , Zhongyuan Tu
    • , Ning Kang
    • , Nan Li
    • , Ying Xu
    • , Xiaobo Wang
    • , Fei Shu
    • , Libing Mu
    • , Tengfei Li
    • , Wenran Ren
    • , Xin Lin
    • , Jun Zhu
    • , Xiaohong Fang
    • , Matthias W. Amrein
    • , Weihui Wu
    • , Li-Tang Yan
    • , Junhong Lü
    • , Tie Xia
    •  & Yan Shi
  • Research | | open

    Typhoid fever is caused by the bacterium Salmonella Typhi. Here, Park et al. analyse the genomes of 249 S. Typhi isolates from 11 sub-Saharan African countries, identifying genes and plasmids associated with antibiotic resistance and showing that multi-drug resistance is highly pervasive in sub-Saharan Africa.

    • Se Eun Park
    • , Duy Thanh Pham
    • , Christine Boinett
    • , Vanessa K. Wong
    • , Gi Deok Pak
    • , Ursula Panzner
    • , Ligia Maria Cruz Espinoza
    • , Vera von Kalckreuth
    • , Justin Im
    • , Heidi Schütt-Gerowitt
    • , John A. Crump
    • , Robert F. Breiman
    • , Yaw Adu-Sarkodie
    • , Ellis Owusu-Dabo
    • , Raphaël Rakotozandrindrainy
    • , Abdramane Bassiahi Soura
    • , Abraham Aseffa
    • , Nagla Gasmelseed
    • , Karen H. Keddy
    • , Jürgen May
    • , Amy Gassama Sow
    • , Peter Aaby
    • , Holly M. Biggs
    • , Julian T. Hertz
    • , Joel M. Montgomery
    • , Leonard Cosmas
    • , Beatrice Olack
    • , Barry Fields
    • , Nimako Sarpong
    • , Tsiriniaina Jean Luco Razafindrabe
    • , Tiana Mirana Raminosoa
    • , Leon Parfait Kabore
    • , Emmanuel Sampo
    • , Mekonnen Teferi
    • , Biruk Yeshitela
    • , Muna Ahmed El Tayeb
    • , Arvinda Sooka
    • , Christian G. Meyer
    • , Ralf Krumkamp
    • , Denise Myriam Dekker
    • , Anna Jaeger
    • , Sven Poppert
    • , Adama Tall
    • , Aissatou Niang
    • , Morten Bjerregaard-Andersen
    • , Sandra Valborg Løfberg
    • , Hye Jin Seo
    • , Hyon Jin Jeon
    • , Jessica Fung Deerin
    • , Jinkyung Park
    • , Frank Konings
    • , Mohammad Ali
    • , John D. Clemens
    • , Peter Hughes
    • , Juliet Nsimire Sendagala
    • , Tobias Vudriko
    • , Robert Downing
    • , Usman N. Ikumapayi
    • , Grant A. Mackenzie
    • , Stephen Obaro
    • , Silvia Argimon
    • , David M. Aanensen
    • , Andrew Page
    • , Jacqueline A. Keane
    • , Sebastian Duchene
    • , Zoe Dyson
    • , Kathryn E. Holt
    • , Gordon Dougan
    • , Florian Marks
    •  & Stephen Baker
  • Research |

    Autophagy-related proteins ATG16L1, ATG5 and ATG12 are required for plasma membrane repair and help to restrict Listeria monocytogenes toxin-mediated cell-to-cell spread.

    • Joel M. J. Tan
    • , Nora Mellouk
    • , Suzanne E. Osborne
    • , Dustin A. Ammendolia
    • , Diana N. Dyer
    • , Ren Li
    • , Diede Brunen
    • , Jorik M. van Rijn
    • , Ju Huang
    • , Mark A. Czuczman
    • , Marija A. Cemma
    • , Amy M. Won
    • , Christopher M. Yip
    • , Ramnik J. Xavier
    • , Donna A. MacDuff
    • , Fulvio Reggiori
    • , Jayanta Debnath
    • , Tamotsu Yoshimori
    • , Peter K. Kim
    • , Gregory D. Fairn
    • , Etienne Coyaud
    • , Brian Raught
    • , Aleixo M. Muise
    • , Darren E. Higgins
    •  & John H. Brumell
    Nature Microbiology 3, 1472–1485
  • Research | | open

    Salmonella employ a range of strategies to counter host defences during infection. Here, Aulicino et al. use single-cell RNA-sequencing to examine the effects of invasive and non-invasive strains of Salmonella, revealing discrete and divergent immune evasion strategies in infected and bystander dendritic cells.

    • Anna Aulicino
    • , Kevin C. Rue-Albrecht
    • , Lorena Preciado-Llanes
    • , Giorgio Napolitani
    • , Neil Ashley
    • , Adam Cribbs
    • , Jana Koth
    • , B. Christoffer Lagerholm
    • , Tim Ambrose
    • , Melita A. Gordon
    • , David Sims
    •  & Alison Simmons

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