Bacterial immune evasion

Bacterial immune evasion is the process by which bacteria avoid and antagonize the bacterial host response, which is mediated by the host's immune system.

Latest Research and Reviews

News and Comment

  • News & Views |

    Host cells assemble linear ubiquitin chains to activate immune signalling during bacterial infection. A new study reveals that Legionella pneumophila — the causative agent of Legionnaires’ disease — produces an enzyme that specifically disassembles these linear ubiquitin modifications to restrict immune responses.

    • Rune Busk Damgaard
    •  & Jonathan N. Pruneda
    Nature Microbiology 4, 1244-1245
  • Research Highlights |

    This study found that a lipase secreted by the opportunistic pathogen Staphylococcus aureus promotes immune evasion.

    • Ashley York
  • News & Views |

    Molecular players involved in systemic and acute infections are relatively easy to pinpoint, whereas bacterial resilience during chronic infections remains less well understood. Pseudomonas aeruginosa encodes a quorum-regulated virulence factor, TesG, that promotes chronic lung infection by suppressing host inflammatory responses.

    • Alain Filloux
    •  & Jane C. Davies
    Nature Microbiology 4, 378-379