Bacterial genomics

This month’s Genome Watch highlights the genomic traits underlying the ancestral association between endobacteria, which live inside arbuscular mycorrhizal fungi, which reside within plants.

A large genome dataset investigates the evolutionary history of Helicobacter pylori and its links to human migration.

This month’s Genome Watch highlights a set of single-cell approaches that yield powerful insights into microbial biology.

This month’s Genome Watch article discusses the role of within-host adaptive evolution in bacterial pathogens for colonization and invasion of their human hosts.

Bacterial species that have eluded cultivation are selectively brought into culture.

Since the emergence of methicillin-resistant Staphylococcus aureus 60 years ago, scientists have been trying to engineer β-lactam antibiotics to restore drug susceptibility. Genomic data now shows that clavulanic acid (a β-lactamase inhibitor) can restore susceptibility in many strains, but only if they carry key mutations.