Archaeal genetics articles from across Nature Portfolio

Archaeal genetics is the scientific study of the genes, consisting of hereditary units, of Archaea, a domain of organisms that comprise single, nucleus-free cells, distinct from bacteria and eukaryotes.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    This study reports that the archaeal chromosome is organized into two compartments with differential gene expression activities that are maintained by a novel Sulfolobus-encoded structural maintenance of chromosomes protein.

    • Andrea Du Toit
  • News |

    This month’s Genome Watch highlights the unique evolutionary history, metabolic functions, and newly identified viruses and associated mobile genetic elements for the highly abundant and ubiquitous ammonia-oxidizing archaea.

    • Emiley A. Eloe-Fadrosh
  • Editorial |

    Although the spotlight on CRISPR–Cas systems has shone on their immense potential as genome-editing tools, the field’s origins are rooted in the microbiology of phage–bacterium interactions. Furthering our understanding of these processes can uncover more systems and generate new reagents with revolutionary properties.

  • Research Highlights |

    In bacteria and archaea, CRISPR-Cas adaptive immune systems utilize RNA-guided endonucleases to defend against invasion by foreign nucleic acids of bacteriophage, virus and plasmid origin. In a recent paper published in Nature, Burstein et al. identified the first Cas9 protein in uncultivated archaea and two novel CRISPR-CasX and CRISPR-CasY systems in uncultivated bacteria by capitalizing on analysis of terabase-scale metagenomic datasets from natural uncultivated organisms.

    • Hui Yang
    •  & Dinshaw J Patel
    Cell Research 27, 313-314