Applications of AFM

Applications of atomic force microscopy (AFM) include biochemistry applications (imaging the structure of biological molecules, cellular components, cells or tissues), chemistry, materials science and nanotechnology applications (imaging of polymers, nanostructures or other materials) and physics and biophysics applications (measuring forces between the AFM tip and the sample surface).

Latest Research and Reviews

News and Comment

  • News & Views |

    Single-cell force spectroscopy reveals rapid, biphasic integrin activation and reinforcement of cell–matrix bonds during the initial steps of fibroblast adhesion.

    • Ning Wang
    Nature Materials 16, 1173-1174
  • News & Views |

    DNA origami nanostructures were utilized to replicate a seed pattern that resulted in the growth of populations of nanostructures. Exponential growth could be controlled by environmental conditions depending on the preferential requirements of each population.

    • Friedrich C. Simmel
    Nature Materials 16, 974-976
  • News & Views |

    The ambiguous barrier mechanism of nuclear pore complexes has now been resolved through structural analysis with high-speed atomic force microscopy.

    • Victor Shahin
    Nature Nanotechnology 11, 658-659
  • News & Views |

    Nanomechanical sensors can now detect femtomolar concentrations of analytes within minutes without the need to passivate the underlying cantilever surface.

    • Gajendra S. Shekhawat
    •  & Vinayak P. Dravid
    Nature Nanotechnology 10, 830-831
  • News & Views |

    The response of bacteria to antibiotics can be quickly assessed by monitoring the fluctuations of cantilevers coated with the bacteria.

    • Rachel A. McKendry
    •  & Natascha Kappeler