Antimicrobial resistance

This study reports that Acinetobacter baumannii establishes intracellular reservoirs in the bladder that can seed recurrent infections following catheterization.

This study comprehensively assesses the fitness cost of mutations conferring resistance to an antifungal drug, revealing a steep resistance–function trade-off.

A single-cell microfluidics study shows that phenotypic heterogeneity and fast growth can reduce antibiotic susceptibility.

Studying malaria transmission biology using scRNA-sequencing provides information on within-host strain diversity and transcriptional states. Here, we comment on our collaborative efforts at establishing single-cell capacities in sub-Saharan Africa and the challenges encountered in Mali’s endemic setting.

Experimental evolution experiments show that antibiotic resistance development decreases thermal tolerance and niche breadth.