Antibacterial drug resistance

Antibacterial drug resistance is the process that bacteria use to tolerate and overcome the effects of antibiotic drugs. Resistance can arise through mutations or can be acquired from other bacteria through plasmids.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    This study shows that although colistin resistance in Klebsiella pneumoniae is associated with a fitness defect in gut colonization, it increases bacterial survival outside the host, thus enabling efficient host-to-host transmission.

    • Andrea Du Toit
  • Research Highlights |

    The successful treatment of polymicrobial infections is difficult, in part owing to inter-species interactions, which can alter antibiotic susceptibility of the bacteria. This study, focusing on cystic fibrosis, shows that multi-drug resistant Stenotrophomonas maltophilia can provide protection against imipenem to sensitive Pseudomonas aeruginosa.

    • Andrea Du Toit
  • Research Highlights |

    This study developed an assay to screen for drugs that inhibit transfer of antimicrobial resistance plasmids between bacteria.

    • Ursula Hofer