Acne vulgaris articles from across Nature Portfolio

Latest Research and Reviews

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  Functional divergence of a bacterial enzyme promotes healthy or acneic skin

  Cutibacterium acnes phylotypes can be catalogued based on their association with acneic or healthy skin. Here, Hajam et al show that the functional divergence of a hyaluronidase enzyme expressed by the phylotypes is a major determinant of acne severity.

  • Irshad A. Hajam
  • Madhusudhanarao Katiki
  • George Y. Liu

  ResearchOpen Access05 Dec 2023 Nature Communications

  Volume: 14, P: 8061
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  Optimization, characterization, and follicular targeting assessment of tretinoin and bicalutamide loaded niosomes

  • Parisa Ghasemiyeh
  • Fatemeh Moradishooli
  • Soliman Mohammadi-Samani

  ResearchOpen Access16 Nov 2023 Scientific Reports

  Volume: 13, P: 20023
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  Whole genome sequencing identifies genetic variants associated with neurogenic inflammation in rosacea

  Rosacea is a common, multi-factorial chronic inflammatory skin disorder. Here authors provide evidence of genetic predisposition by whole genome sequencing and whole exome sequencing of samples from familial cases, and by recapitulating a recurrent mutation in the LRRC4 gene in a mouse model, they find that neuron-derived vasoactive intestinal peptide is an important pathogenic factor for neurogenic inflammation in rosacea.’

  • Zhili Deng
  • Mengting Chen
  • Ji Li

  ResearchOpen Access05 Jul 2023 Nature Communications

  Volume: 14, P: 3958
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  Topical phage therapy in a mouse model of Cutibacterium acnes-induced acne-like lesions

  Bacteriophage therapy is evolving as a promising approach to tackling bacterial infection, even in the case of emerging antibiotic resistance. In this work, authors present the topical application of numerous Cutibacterium acnes phage in an in vivo mouse model of acne vulgaris.

  • Amit Rimon
  • Chani Rakov
  • Ronen Hazan

  ResearchOpen Access22 Feb 2023 Nature Communications

  Volume: 14, P: 1005
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  Genome-wide association meta-analysis identifies 29 new acne susceptibility loci

  Better understanding of the genetic basis of acne can pave the way to more effective treatments. Here, the authors perform a genome-wide association study meta-analysis of >20,000 cases and identify 29 new acne susceptibility loci, uncovering genetic links to Mendelian hair and skin disorders and other complex traits.

  • Brittany L. Mitchell
  • Jake R. Saklatvala
  • Michael A. Simpson

  ResearchOpen Access07 Feb 2022 Nature Communications

  Volume: 13, P: 702
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  Photoactivated cell-killing amino-based flavylium compounds

  • Hélder Oliveira
  • Paula Araújo
  • Iva Fernandes

  ResearchOpen Access09 Nov 2021 Scientific Reports

  Volume: 11, P: 22005