Signal Transduction and Targeted Therapy

Camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and hepatic artery infusion chemotherapy for hepatocellular carcinoma in Barcelona Clinic Liver Cancer stage C (TRIPLET): a phase II study

Tian-Qi Zhang
Zhi-Jun Geng
Yang-Kui Gu

Article 27 October 2023

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Characteristics of premanufacture CD8⁺ T cells determine CAR-T efficacy in patients with diffuse large B-cell lymphoma

Yao Wang
Chuan Tong
Weidong Han
ArticleOpen Access25 Oct 2023
Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDKN2A

Javier Martin-Broto
Jeronimo Martinez-Garcia
Nadia Hindi
ArticleOpen Access25 Oct 2023
Safety and clinical efficacy of sintilimab (anti-PD-1) in pediatric patients with advanced or recurrent malignancies in a phase I study

Yi Que
Juan Wang
Yizhuo Zhang
ArticleOpen Access13 Oct 2023
SARS-CoV-2 spike-specific T_FH cells exhibit unique responses in infected and vaccinated individuals

Rongzhang He
Xingyu Zheng
Xiaowang Qu
ArticleOpen Access06 Oct 2023

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Behind the Paper

In these Behind the Paper posts, our authors share the real stories behind the latest research papers, from conception to publication, the highs and the lows.
Outstanding Editorial Board Members

Based on the academic activity and contribution to the development of the STTT in 2021-2022, the editorial office selected 10 outstanding editorial board members to be awarded the “STTT 2022 Outstanding Editorial Board Award”, and sincerely thanked all editorial board members and fellow experts for their strong support to the development of STTT.
Outstanding Reviewers

According to the quality, quantity and speed of review in 2021-2022, the editorial office selected 10 reviewers to be awarded the “STTT 2022 Outstanding Reviewers Award”. We are no less grateful to the many more reviewers not named.

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Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

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Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

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Research HighlightOpen Access30 Nov 2023

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Camrelizumab (a PD-1 inhibitor) plus apatinib (an VEGFR-2 inhibitor) and hepatic artery infusion chemotherapy for hepatocellular carcinoma in Barcelona Clinic Liver Cancer stage C (TRIPLET): a phase II study

Featured

Characteristics of premanufacture CD8⁺ T cells determine CAR-T efficacy in patients with diffuse large B-cell lymphoma

Phase II trial of CDK4/6 inhibitor palbociclib in advanced sarcoma based on mRNA expression of CDK4/CDKN2A

Safety and clinical efficacy of sintilimab (anti-PD-1) in pediatric patients with advanced or recurrent malignancies in a phase I study

SARS-CoV-2 spike-specific T_FH cells exhibit unique responses in infected and vaccinated individuals

Announcements

Behind the Paper

Outstanding Editorial Board Members

Outstanding Reviewers

Browse articles

IgE-Mast cell mediated allergy: a sensor of food quality

Antigen-induced chimeric antigen receptor multimerization amplifies on-tumor cytotoxicity

Tau in the pancreas: understanding the link between type 2 diabetes mellitus and Alzheimer’s disease

Managing type 2 diabetes: targeting a microbial enzyme as a novel treatment option

Gut liver brain axis in diseases: the implications for therapeutic interventions

Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

Neoadjuvant nivolumab with or without platinum-doublet chemotherapy based on PD-L1 expression in resectable NSCLC (CTONG1804): a multicenter open-label phase II study

Going only half the way: cell cycle exit after the G1 restriction point

SARS-CoV-2 Omicron subvariant BA.2.86: limited potential for global spread

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ACE2-independent infection of T lymphocytes by SARS-CoV-2

SARS-CoV-2 infection causes immunodeficiency in recovered patients by downregulating CD19 expression in B cells via enhancing B-cell metabolism

Alterations in microbiota of patients with COVID-19: potential mechanisms and therapeutic interventions

Fe65-engineered neuronal exosomes encapsulating corynoxine-B ameliorate cognition and pathology of Alzheimer’s disease

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