Showing 1–50 of 2199 results

  1. Research | | Open

  2. Research | | Open

    • ...including severe acute respiratory syndrome coronavirus (SARS-CoV) and 2019 novel coronavirus (2019-nCoV, also known as SARS-CoV-2), lead global epidemics... ...currently no effective drugs targeting 2019-nCoV/SARS-CoV-2. Drug repurposing, representing... ...between the HCoV–host interactome...HCoV
  3. Research | | Open

  4. Reviews | | Open

    • 2019-nCoV epidemic was firstly reported at... ...caused a global outbreak of COVID-19 now. Saliva, a biofluid... ...oral cavity, has been reported 2019-nCoV nucleic acid positive. Besides... ...are possibly another hosts of 2019-nCoV due to expression of ACE2... ...mode for 2019-nCoV to disseminate...
  5. Research | | Open

    • ...have caused three zoonotic outbreaks, SARS-CoV in 2002–2003, MERS-CoV in 2012, and the... newly emerged SARS-CoV-2 in late 2019.... ...known about the biology of SARS-CoV-2. Here, using SARS-CoV-2 S protein pseudovirus system... ...hACE2) is the receptor for SARS-CoV-2, find that SARS-CoV-2...
  6. Reviews | | Open

    • A novel β-coronavirus (2019-nCoV) caused severe and even... ...China and other countries. The 2019-nCoV was different from SARS-CoV, but shared the same... ...). The natural host of 2019-nCoV may be the bat Rhinolophus... affinis as 2019-nCoV showed 96.2% of... ...routes of 2019-nCoV... ...2019-nCoV...
  7. Reviews |

    • Severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory... syndrome coronavirus (MERS-CoV) are two highly transmissible... ...coronaviruses that are related to SARS-CoV and MERS-CoV were discovered in bats worldwide... ...acute diarrhoea syndrome coronavirus (SADS-CoV)...
  8. Reviews |

  9. Reviews |

    • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative... agent of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into... the virology of SARS-CoV-2, understanding the fundamental... ...clinical manifestations of COVID-19 is vital for...
  10. Research | | Open

  11. Research |

    • ...betacoronavirus severe acute respiratory syndrome (SARS)-CoV-2 began in Wuhan,... China in December 2019. COVID-19, the disease associated with SARS-CoV-2 infection, rapidly spread... ...flow assay for detection of SARS-CoV-2 from respiratory swab RNA... ...patients with COVID-19 infection...
  12. Comments and Opinion | | Open

  13. Reviews | | Open

    • ...success” in development of human coronavirus vaccines, particularly SARS-CoV-2, a third, related... ...respectively, while testing and deploying COVID-19 vaccines is predicted to increase... ...demonstrating vaccine efficacy and controlling SARS-CoV-2 infection, disease, death...
  14. Reviews |

  15. Reviews | | Open

  16. Reviews |

    • ...and efficacy of corticosteroids in SARS-CoV-2, SARS-CoV, and MERS-CoV infections. We searched PubMed,... ...operators and search terms covering SARS-CoV-2, SARS-CoV, OR MERS-CoV AND corticosteroids to find appropriate... ...corticosteroid use in subjects with SARS-CoV-2, SARS-CoV, and MERS-CoV...
  17. Research | | Open

    • ...The Netherlands in 2004, human coronavirus NL63 (HCoV-NL63) was found to... ...worldwide infections. Patients infected by HCoV-NL63 are typically young children... ...effective antiviral therapy to contain HCoV-NL63 infection. CoV genomes... ...the crystal structure of HCoV-NL63 Mpro in complex...
  18. Research |

    • A novel human coronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), has caused outbreaks of... ...bundle fusion core structure of MERS-CoV spike protein S2 subunit by... ...fusion core structure, suggesting that MERS-CoV enters into the host cell... ...inhibit MERS-CoV... ...MERS-CoV...
  19. Research |

    • ...understand the molecular basis of coronavirus attachment to oligosaccharide receptors,... ...determined cryo-EM structures of coronavirus OC43 S glycoprotein trimer in... ...site is conserved in all coronavirus S glycoproteins that engage 9... ...pockets of coronavirus hemagglutinin...
  20. News |

  21. Research |

    • The threat of a major coronavirus pandemic urges the development of... ...to combat these pathogens. Human coronavirus NL63 (HCoV-NL63) is an α-coronavirus that can cause severe lower... ...cryo-EM reconstruction of the HCoV-NL63 coronavirus spike glycoprotein trimer, which... ...that HCoV-NL63...
  22. Research | | Open

    • ...emergence of the novel human coronavirus SARS-CoV-2 in Wuhan, China... ...worldwide epidemic of respiratory disease (COVID-19). Vaccines and targeted therapeutics... ...human monoclonal antibody that neutralizes SARS-CoV-2 (and SARS-CoV) in cell culture. This... ...and treatment of COVID-19...
  23. Reviews |

    • ...about the perinatal aspects of COVID-19. Objective To summarize available... ...Analysis of available literature on COVID-19 using Medline and Google scholar... ...occurs very rarely. Consequences of COVID-19 infection among women during early...
  24. Research | | Open

  25. Research |

    • Coronavirus disease 2019 (COVID-19) is an acute infection... ...are reports of cases of COVID-19 in which the patient shows... ...analysis of nine cases of COVID-19 that provides proof of active... ...rapid decline in viral load. COVID-19 can present as a mild... ...for the containment of COVID-19...
  26. Comments and Opinion |

    • Coronavirus disease 2019 (COVID-19) is caused by severe... acute respiratory syndrome coronavirus 2, which invades a... .... However, evidence suggests that COVID-19 infection also has implications for... ...should be considered when treating COVID-19.
  27. Correspondence |

  28. News |

  29. Research | | Open

    • ...control and prevent the current COVID-19 pandemic, the development of... ...immune target epitopes of novel coronavirus (SARS-CoV-2) to induce host... ...potential epitopes derived from the SARS-CoV-2 sequences for HLAs commonly... ...have high homologies to SARS-CoV. To further select commonly...
  30. Comments and Opinion |

    • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells... ...through ACE2 receptors, leading to coronavirus disease (COVID-19)-related pneumonia, while also... ...cardiovascular protection during treatment for COVID-19.
  31. Reviews |

    • Coronavirus disease 19 (COVID-19) has been described to... ...regarding severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and ocular structures... ...information on the presence of SARS-CoV-2 in cornea, conjunctiva,... ...letter. Globally, 252 SARS-CoV-2 infected patients were...
  32. Reviews |

    • The COVID-19 pandemic caused by infection with... SARS-CoV-2 has led to more... ...the hyperinflammatory response induced by SARS-CoV-2 is a major cause... ...infections with the related virus SARS-CoV. Here we describe the... ...roles of macrophages during SARS-CoV-2 infection and discuss...
  33. Research | | Open

    • ...and characterization of a new coronavirus (2019-nCoV), which caused an epidemic... ...79.6% sequence identity to SARS-CoV. Furthermore, we show that... 2019-nCoV is 96% identical at... ...-genome level to a bat coronavirus. Pairwise protein sequence analysis... ...In addition, 2019-nCoV virus...
  34. Research | | Open

    • COVID-19, caused by SARS-CoV-2, has recently affected... ...states during the course of COVID-19 remain unclear. We sought... ...during the recovery stage of COVID-19 by single-cell RNA sequencing... ...recovery stage (ERS) of COVID-19. There was an increased... ...with SARS-CoV-2... ...COVID-19...
  35. Correspondence |

  36. News |

  37. Research |

    • ...fatal, respiratory illness. Since SARS-CoV was first identified in animal... ...projects have discovered thousands of coronavirus sequences in diverse animals and... ...lineage B betacoronaviruses, such as SARS-CoV and the recent SARS-CoV-2, for receptor usage... ...recently emerging SARS-CoV...
  38. Reviews |

    • ...of Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 marked the... ...introduction of a highly pathogenic coronavirus into the human population in... ...century. The continuing introductions of MERS-CoV from dromedary camels, the... ...severe acute respiratory syndrome coronavirus...
  39. Research | | Open

    • The outbreak of 2019 novel coronavirus disease (Covid-19) caused by SARS-CoV-2 has spread rapidly,... ...and political crisis. Currently, SARS-CoV-2 RNA detection in nasopharyngeal... ...samples with RT-qPCR-confirmed SARS-CoV-2 infection and 40 negative... ...to reduce SARS-CoV-2 transmission...
  40. Research |

    • A novel coronavirus—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—emerged in humans... ...the confirmed case count of coronavirus disease 2019 (COVID-19) had surpassed 2 million.... ...on full-genome sequence analysis, SARS-CoV-2 shows high homology to... ...to SARS-CoV-2...
  41. Research | | Open

    • Severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 as... ...and host species tropism. As SARS-CoV enters host cells, the... ...recently developed stabilizing mutations for coronavirus spikes that prevent the transition... ...of a stabilized trimeric SARS-CoV S, as well...
  42. Research |

    • The Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe and often... ...initiated via binding of the MERS-CoV spike (S) glycoprotein to... ...receptors, respectively). To understand MERS-CoV engagement of sialylated receptors,... ...is essential for MERS-CoV S-mediated attachment...
  43. Reviews |

    • ...rapid spread of a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to... an ongoing pandemic of coronavirus disease 2019 (COVID-19). Recently, angiotensin-converting... ...be a functional receptor for SARS-CoV-2 to enter host target... ...COVID-19. On...
  44. Research | | Open

    • Coronavirus disease 2019 (COVID-19), caused by the novel... human coronavirus SARS-CoV-2, is currently a... ...to block viral entry. Both SARS-CoV-2 and SARS-CoV share this mechanism. Here... ...that immunization with either the SARS-CoV RBD or SARS-CoV-2 RBD was able to... ...against SARS-CoV...
  45. Correspondence |

  46. Research | | Open

  47. Research |

  48. Research |

  49. Reviews |

  50. Comments and Opinion |