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Research | 24 September 2020 | Open
ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration
- Gururaj Rao Kidiyoor
- , Qingsen Li
- , Giulia Bastianello
- , Christopher Bruhn
- , Irene Giovannetti
- , Adhil Mohamood
- , Galina V. Beznoussenko
- , Alexandre Mironov
- , Matthew Raab
- , Matthieu Piel
- , Umberto Restuccia
- , Vittoria Matafora
- , Angela Bachi
- , Sara Barozzi
- , Dario Parazzoli
- , Emanuela Frittoli
- , Andrea Palamidessi
- , Tito Panciera
- , Stefano Piccolo
- , Giorgio Scita
- , Paolo Maiuri
- , Kristina M. Havas
- , Zhong-Wei Zhou
- , Amit Kumar
- , Jiri Bartek
- , Zhao-Qi Wang
- & Marco Foiani
Nature Communications 11 , 1–16

Rights & permissionsfor article ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration . Opens in a new window.
Research | 1 December 1997
Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis
Nature Genetics 17 , 479–482

Rights & permissionsfor article Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis . Opens in a new window.
Research | 10 April 2005
An essential function for NBS1 in the prevention of ataxia and cerebellar defects
- Pierre-Olivier Frappart
- , Wei-Min Tong
- , Ilja Demuth
- , Ivan Radovanovic
- , Zdenko Herceg
- , Adriano Aguzzi
- , Martin Digweed
- & Zhao-Qi Wang
Nature Medicine 11 , 538–544

Rights & permissionsfor article An essential function for NBS1 in the prevention of ataxia and cerebellar defects . Opens in a new window.
Research | 31 December 1992
Bone and haematopoietic defects in mice lacking c-fos
Nature 360 , 741–745

Rights & permissionsfor article Bone and haematopoietic defects in mice lacking c-fos . Opens in a new window.
Research | 1 March 1997
The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo
- Farhad Hafezi
- , Joachim P. Steinbach
- , Andreas Marti
- , Kurt Munz
- , Zhao-Qi Wang
- , Erwin F. Wagner
- , Adriano Aguzzi
- & Charlotte E. Remé
Nature Medicine 3 , 346–349

Rights & permissionsfor article The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo . Opens in a new window.
Research | 1 September 1999
Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability
Nature Genetics 23 , 76–80

Rights & permissionsfor article Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability . Opens in a new window.
Research | 1 December 1994
Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene
Nature 372 , 464–467

Rights & permissionsfor article Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene . Opens in a new window.
Research | 1 March 1999
Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin
- Volker Burkart
- , Zhao-Qi Wang
- , Jürgen Radons
- , Birgit Heller
- , Zdenko Herceg
- , Laura Stingl
- , Erwin F. Wagner
- & Hubert Kolb
Nature Medicine 5 , 314–319

Rights & permissionsfor article Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin . Opens in a new window.
15 March 2004
Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks
- Yun-Gui Yang
- , Ulrich Cortes
- , Srinivas Patnaik
- , Maria Jasin
- & Zhao-Qi Wang
Oncogene 23 , 3872–3882

Rights & permissionsfor article Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks . Opens in a new window.
12 March 2001
Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool
- Jun-Li Luo
- , Qin Yang
- , Wei-Min Tong
- , Manfred Hergenhahn
- , Zhao-Qi Wang
- & Monica Hollstein
Oncogene 20 , 320–328

Rights & permissionsfor article Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool . Opens in a new window.
28 August 1997
Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase
Oncogene 15 , 1035–1041

Rights & permissionsfor article Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase . Opens in a new window.
Research | 4 September 2001
Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression
- Zdenko Herceg
- , Wolfgang Hulla
- , David Gell
- , Cyrille Cuenin
- , Matilde Lleonart
- , Stephen Jackson
- & Zhao-Qi Wang
Nature Genetics 29 , 206–211

Rights & permissionsfor article Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression . Opens in a new window.
Research | 14 June 2019 | Open
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice
- Tobias Ackermann
- , Götz Hartleben
- , Christine Müller
- , Guido Mastrobuoni
- , Marco Groth
- , Britt A. Sterken
- , Mohamad A. Zaini
- , Sameh A. Youssef
- , Hidde R. Zuidhof
- , Sara R. Krauss
- , Gertrud Kortman
- , Gerald de Haan
- , Alain de Bruin
- , Zhao-Qi Wang
- , Matthias Platzer
- , Stefan Kempa
- & Cornelis F. Calkhoven
Communications Biology 2 , 1–15

Rights & permissionsfor article C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice . Opens in a new window.
Research | 21 December 2016
XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia
- Nicolas C. Hoch
- , Hana Hanzlikova
- , Stuart L. Rulten
- , Martine Tétreault
- , Emilia Komulainen
- , Limei Ju
- , Peter Hornyak
- , Zhihong Zeng
- , William Gittens
- , Stephanie A. Rey
- , Kevin Staras
- , Grazia M. S. Mancini
- , Peter J. McKinnon
- , Zhao-Qi Wang
- , Justin D. Wagner
- , Kym Boycott
- , Alex MacKenzie
- , Jacek Majewski
- , Michael Brudno
- , Dennis Bulman
- , David Dyment
- , Grace Yoon
- & Keith W. Caldecott
Nature 541 , 87–91

Rights & permissionsfor article XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia . Opens in a new window.
Research | 20 December 2013
Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation
- WooKee Min
- , Christopher Bruhn
- , Paulius Grigaravicius
- , Zhong-Wei Zhou
- , Fu Li
- , Anja Krüger
- , Bénazir Siddeek
- , Karl-Otto Greulich
- , Oliver Popp
- , Chris Meisezahl
- , Cornelis F. Calkhoven
- , Alexander Bürkle
- , Xingzhi Xu
- & Zhao-Qi Wang
Nature Communications 4 , 1–14

Rights & permissionsfor article Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation . Opens in a new window.
Research | 3 January 2012 | Open
A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons
- Rui Li
- , Yun-Gui Yang
- , Yunzhou Gao
- , Zhao-Qi Wang
- & Wei-Min Tong
Cell Research 22 , 859–872

Rights & permissionsfor article A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons . Opens in a new window.
Research | 25 September 2011
MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway
Nature Cell Biology 13 , 1325–1334

Rights & permissionsfor article MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway . Opens in a new window.
Research | 11 December 2005
Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks
- Rabih Murr
- , Joanna I. Loizou
- , Yun-Gui Yang
- , Cyrille Cuenin
- , Hai Li
- , Zhao-Qi Wang
- & Zdenko Herceg
Nature Cell Biology 8 , 91–99

Rights & permissionsfor article Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks . Opens in a new window.
Research | 1 October 1997
Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia
- Mikael J.L. Eliasson
- , Kenji Sampei
- , Allen S. Mandir
- , Patricia D. Hurn
- , Richard J. Traystman
- , Jun Bao
- , Andrew Pieper
- , Zhao-Qi Wang
- , Ted M. Dawson
- , Solomon H. Snyder
- & Valina L. Dawson
Nature Medicine 3 , 1089–1095

Rights & permissionsfor article Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia . Opens in a new window.

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ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration

Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis

An essential function for NBS1 in the prevention of ataxia and cerebellar defects

Bone and haematopoietic defects in mice lacking c-fos

The absence of c-fos prevents light-induced apoptotic cell death of photoreceptors in retinal degeneration in vivo

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability

Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin

Ablation of PARP-1 does not interfere with the repair of DNA double-strand breaks, but compromises the reactivation of stalled replication forks

Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool

Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase

Disruption of Trrap causes early embryonic lethality and defects in cell cycle progression

C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activation

A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons

MCPH1 regulates the neuroprogenitor division mode by coupling the centrosomal cycle with mitotic entry through the Chk1–Cdc25 pathway

Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks

Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia

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