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Research | 19 December 2019 | Open
Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress
- Zhiyuan You
- , Wen-Xue Jiang
- , Ling-Yun Qin
- , Zhou Gong
- , Wei Wan
- , Jin Li
- , Yusha Wang
- , Hongtao Zhang
- , Chao Peng
- , Tianhua Zhou
- , Chun Tang
- & Wei Liu
Nature Communications 10 , 1–14

Rights & permissionsfor article Requirement for p62 acetylation in the aggregation of ubiquitylated proteins under nutrient stress . Opens in a new window.
Research | 1 July 2020 | Open
Human papillomavirus vaccine-associated premature ovarian insufficiency and related adverse events: data mining of Vaccine Adverse Event Reporting System
- Li Gong
- , Huan-huan Ji
- , Xue-wen Tang
- , Ling-yun Pan
- , Xiao Chen
- & Yun-tao Jia
Scientific Reports 10 , 1–8

Rights & permissionsfor article Human papillomavirus vaccine-associated premature ovarian insufficiency and related adverse events: data mining of Vaccine Adverse Event Reporting System . Opens in a new window.
Research | 8 October 2020 | Open
JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency
- Yinghua Huang
- , Hui Zhang
- , Lulu Wang
- , Chuanqing Tang
- , Xiaogan Qin
- , Xinyu Wu
- , Meifang Pan
- , Yujia Tang
- , Zhongzhou Yang
- , Isaac A. Babarinde
- , Runxia Lin
- , Guanyu Ji
- , Yiwei Lai
- , Xueting Xu
- , Jianbin Su
- , Xue Wen
- , Takashi Satoh
- , Tanveer Ahmed
- , Vikas Malik
- , Carl Ward
- , Giacomo Volpe
- , Lin Guo
- , Jinlong Chen
- , Li Sun
- , Yingying Li
- , Xiaofen Huang
- , Xichen Bao
- , Fei Gao
- , Baohua Liu
- , Hui Zheng
- , Ralf Jauch
- , Liangxue Lai
- , Guangjin Pan
- , Jiekai Chen
- , Giuseppe Testa
- , Shizuo Akira
- , Jifan Hu
- , Duanqing Pei
- , Andrew P. Hutchins
- , Miguel A. Esteban
- & Baoming Qin
Nature Communications 11 , 1–16

Rights & permissionsfor article JMJD3 acts in tandem with KLF4 to facilitate reprogramming to pluripotency . Opens in a new window.
Research | 1 April 2016 | Open
An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design
- Yongping Zhao
- , Congsheng Zhang
- , Wenwen Liu
- , Wei Gao
- , Changlin Liu
- , Gaoyuan Song
- , Wen-Xue Li
- , Long Mao
- , Beijiu Chen
- , Yunbi Xu
- , Xinhai Li
- & Chuanxiao Xie
Scientific Reports 6 , 1–11

Rights & permissionsfor article An alternative strategy for targeted gene replacement in plants using a dual-sgRNA/Cas9 design . Opens in a new window.
Research | 9 February 2016 | Open
Specific cell surface labeling of GPCRs using split GFP
- Wen-Xue Jiang
- , Xu Dong
- , Jing Jiang
- , Yu-Hong Yang
- , Ju Yang
- , Yun-Bi Lu
- , San-Hua Fang
- , Er-Qing Wei
- , Chun Tang
- & Wei-Ping Zhang
Scientific Reports 6 , 1–9

Rights & permissionsfor article Specific cell surface labeling of GPCRs using split GFP . Opens in a new window.
Research | 10 January 2017 | Open
Development of a multiple-hybrid population for genome-wide association studies: theoretical consideration and genetic mapping of flowering traits in maize
- Hui Wang
- , Cheng Xu
- , Xiaogang Liu
- , Zifeng Guo
- , Xiaojie Xu
- , Shanhong Wang
- , Chuanxiao Xie
- , Wen-Xue Li
- , Cheng Zou
- & Yunbi Xu
Scientific Reports 7 , 1–16

Rights & permissionsfor article Development of a multiple-hybrid population for genome-wide association studies: theoretical consideration and genetic mapping of flowering traits in maize . Opens in a new window.
Amendments and Corrections | 9 September 2014
Correction: Corrigendum: Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
- Hao Yin
- , Wen Xue
- , Sidi Chen
- , Roman L Bogorad
- , Eric Benedetti
- , Markus Grompe
- , Victor Koteliansky
- , Phillip A Sharp
- , Tyler Jacks
- & Daniel G Anderson
Nature Biotechnology 32 , 952–952

Rights & permissionsfor article Correction: Corrigendum: Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype . Opens in a new window.
Research | 30 July 2015 | Open
Teleportation of a Toffoli gate among distant solid-state qubits with quantum dots embedded in optical microcavities
- Shi Hu
- , Wen-Xue Cui
- , Dong-Yang Wang
- , Cheng-Hua Bai
- , Qi Guo
- , Hong-Fu Wang
- , Ai-Dong Zhu
- & Shou Zhang
Scientific Reports 5 , 1–9

Rights & permissionsfor article Teleportation of a Toffoli gate among distant solid-state qubits with quantum dots embedded in optical microcavities . Opens in a new window.
Research | 2 May 2014
Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish
- Li-Ting Chen
- , Wen-Xue Liang
- , Shuo Chen
- , Ren-Ke Li
- , Jue-Ling Tan
- , Peng-Fei Xu
- , Liu-Fei Luo
- , Lei Wang
- , Shan-He Yu
- , Guoyu Meng
- , Keqin Kathy Li
- , Ting-Xi Liu
- , Zhu Chen
- & Sai-Juan Chen
Nature Communications 5 , 1–12

Rights & permissionsfor article Functional and molecular features of the calmodulin-interacting protein IQCG required for haematopoiesis in zebrafish . Opens in a new window.
Research | 13 March 2011
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
- Xiao-Jing Yan
- , Jie Xu
- , Zhao-Hui Gu
- , Chun-Ming Pan
- , Gang Lu
- , Yang Shen
- , Jing-Yi Shi
- , Yong-Mei Zhu
- , Lin Tang
- , Xiao-Wei Zhang
- , Wen-Xue Liang
- , Jian-Qing Mi
- , Huai-Dong Song
- , Ke-Qin Li
- , Zhu Chen
- & Sai-Juan Chen
Nature Genetics 43 , 309–315

Rights & permissionsfor article Exome sequencing identifies somatic mutations of DNA methyltransferase gene <i>DNMT3A</i> in acute monocytic leukemia . Opens in a new window.
Amendments and Corrections | 26 May 2011
Erratum: Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
- Wen Xue
- , Lars Zender
- , Cornelius Miething
- , Ross A. Dickins
- , Eva Hernando
- , Valery Krizhanovsky
- , Carlos Cordon-Cardo
- & Scott W. Lowe
Nature 473 , 544–544

Rights & permissionsfor article Erratum: Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas . Opens in a new window.
Research | 24 September 2008
ROS3 is an RNA-binding protein required for DNA demethylation in Arabidopsis
- Xianwu Zheng
- , Olga Pontes
- , Jianhua Zhu
- , Daisuke Miki
- , Fei Zhang
- , Wen-Xue Li
- , Kei Iida
- , Avnish Kapoor
- , Craig S. Pikaard
- & Jian-Kang Zhu
Nature 455 , 1259–1262

Rights & permissionsfor article ROS3 is an RNA-binding protein required for DNA demethylation in <i>Arabidopsis</i> . Opens in a new window.
Research | 1 August 2005
Molecular evolution of the rice miR395 gene family
- Sreelatha GUDDETI
- , De Chun ZHANG
- , Ai Li LI
- , Chuck H LESEBERG
- , Hui KANG
- , Xiao Guang LI
- , Wen Xue ZHAI
- , Mitrick A JOHNS
- & Long MAO
Cell Research 15 , 631–638

Rights & permissionsfor article Molecular evolution of the rice miR395 gene family . Opens in a new window.
Research | 25 February 2019
Adenine base editing in an adult mouse model of tyrosinaemia
- Chun-Qing Song
- , Tingting Jiang
- , Michelle Richter
- , Luke H. Rhym
- , Luke W. Koblan
- , Maria Paz Zafra
- , Emma M. Schatoff
- , Jordan L. Doman
- , Yueying Cao
- , Lukas E. Dow
- , Lihua Julie Zhu
- , Daniel G Anderson
- , David R. Liu
- , Hao Yin
- & Wen Xue
Nature Biomedical Engineering 4 , 125–130

Rights & permissionsfor article Adenine base editing in an adult mouse model of tyrosinaemia . Opens in a new window.
Research | 20 November 2018 | Open
Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming
- Zhonghua Du
- , Lin Jia
- , Yichen Wang
- , Cong Wang
- , Xue Wen
- , Jingcheng Chen
- , Yanbo Zhu
- , Dehai Yu
- , Lei Zhou
- , Naifei Chen
- , Shilin Zhang
- , Ilkay Celik
- , Ferhat Ay
- , Sujun Gao
- , Songling Zhang
- , Wei Li
- , Andrew R. Hoffman
- , Jiuwei Cui
- & Ji-Fan Hu
Scientific Data 5 , 1–8

Rights & permissionsfor article Combined RNA-seq and RAT-seq mapping of long noncoding RNAs in pluripotent reprogramming . Opens in a new window.
Research | 7 February 2018 | Open
Adverse drug events in Chinese pediatric inpatients and associated risk factors: a retrospective review using the Global Trigger Tool
- Huan-huan Ji
- , Lin Song
- , Jian-wen Xiao
- , Yu-xia Guo
- , Ping Wei
- , Ting-ting Tang
- , Xiao-jiang Tian
- , Xue-wen Tang
- & Yun-tao Jia
Scientific Reports 8 , 1–7

Rights & permissionsfor article Adverse drug events in Chinese pediatric inpatients and associated risk factors: a retrospective review using the Global Trigger Tool . Opens in a new window.
Comments and Opinion | 14 February 2018
CRISPR–Cas-related technologies in basic and translational liver research
- Chun-Qing Song
- & Wen Xue
Nature Reviews Gastroenterology & Hepatology 15 , 251–252

Rights & permissionsfor article CRISPR–Cas-related technologies in basic and translational liver research . Opens in a new window.
Research | 16 May 2018 | Open
Clinical, retrospective case-control study on the mechanics of obstacle in mouth opening and malocclusion in patients with maxillofacial fractures
- Hai-Hua Zhou
- , Kun Lv
- , Rong-Tao Yang
- , Zhi Li
- , Xue-Wen Yang
- & Zu-Bing Li
Scientific Reports 8 , 1–8

Rights & permissionsfor article Clinical, retrospective case-control study on the mechanics of obstacle in mouth opening and malocclusion in patients with maxillofacial fractures . Opens in a new window.
Research | 24 April 2020 | Open
Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope
- Tingting Jiang
- , Jordana M. Henderson
- , Kevin Coote
- , Yi Cheng
- , Hillary C. Valley
- , Xiao-Ou Zhang
- , Qin Wang
- , Luke H. Rhym
- , Yueying Cao
- , Gregory A. Newby
- , Hermann Bihler
- , Martin Mense
- , Zhiping Weng
- , Daniel G. Anderson
- , Anton P. McCaffrey
- , David R. Liu
- & Wen Xue
Nature Communications 11 , 1–9

Rights & permissionsfor article Chemical modifications of adenine base editor mRNA and guide RNA expand its application scope . Opens in a new window.
Research | 25 April 2017 | Open
Mutational screening of SLC39A5, LEPREL1 and LRPAP1 in a cohort of 187 high myopia patients
- Chun-Yun Feng
- , Xiao-Qiong Huang
- , Xue-Wen Cheng
- , Rong-Han Wu
- , Fan Lu
- & Zi-Bing Jin
Scientific Reports 7 , 1–9

Rights & permissionsfor article Mutational screening of <i>SLC39A5</i>, <i>LEPREL1</i> and <i>LRPAP1</i> in a cohort of 187 high myopia patients . Opens in a new window.
Research | 18 February 2016 | Open
A Modular Assembly Platform for Rapid Generation of DNA Constructs
Scientific Reports 6 , 1–9

Rights & permissionsfor article A Modular Assembly Platform for Rapid Generation of DNA Constructs . Opens in a new window.
Research | 23 March 2015 | Open
Effects of waterlogging on carbon assimilate partitioning in the Zoigê alpine wetlands revealed by ¹³CO₂ pulse labeling
- Jun-Qin Gao
- , Ju-Juan Gao
- , Xue-Wen Zhang
- , Xing-Liang Xu
- , Zhao-Heng Deng
- & Fei-Hai Yu
Scientific Reports 5 , 1–5

Rights & permissionsfor article Effects of waterlogging on carbon assimilate partitioning in the Zoigê alpine wetlands revealed by <sup>13</sup>CO<sub>2</sub> pulse labeling . Opens in a new window.
Research | 6 May 2015 | Open
Gate Modulation of Graphene-ZnO Nanowire Schottky Diode
- Ren Liu
- , Xu-Chen You
- , Xue-Wen Fu
- , Fang Lin
- , Jie Meng
- , Da-Peng Yu
- & Zhi-Min Liao
Scientific Reports 5 , 1–6

Rights & permissionsfor article Gate Modulation of Graphene-ZnO Nanowire Schottky Diode . Opens in a new window.
Research | 30 March 2014
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
- Hao Yin
- , Wen Xue
- , Sidi Chen
- , Roman L Bogorad
- , Eric Benedetti
- , Markus Grompe
- , Victor Koteliansky
- , Phillip A Sharp
- , Tyler Jacks
- & Daniel G Anderson
Nature Biotechnology 32 , 551–553

Rights & permissionsfor article Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype . Opens in a new window.
Research | 24 January 2007
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
- Wen Xue
- , Lars Zender
- , Cornelius Miething
- , Ross A. Dickins
- , Eva Hernando
- , Valery Krizhanovsky
- , Carlos Cordon-Cardo
- & Scott W. Lowe
Nature 445 , 656–660

Rights & permissionsfor article Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas . Opens in a new window.
6 December 2004
Immunohistochemical analysis of the expression of FATE/BJ-HCC-2 antigen in normal and malignant tissues
- Xiao Ang Yang
- , Xue Yuan Dong
- , Huan Qiao
- , Yue Dan Wang
- , Ji Run Peng
- , Yan Li
- , Xue Wen Pang
- , Chan Tian
- & Wei Feng Chen
Laboratory Investigation 85 , 205–213

Rights & permissionsfor article Immunohistochemical analysis of the expression of FATE/BJ-HCC-2 antigen in normal and malignant tissues . Opens in a new window.
Research | 1 August 2003
HCA587 Antigen Expression in Normal Tissues and Cancers: Correlation with Tumor Differentiation in Hepatocellular Carcinoma
- Bing Li
- , Xiao-Ping Qian
- , Xue-Wen Pang
- , Wan-Zhong Zou
- , Yu-Ping Wang
- , Hong-Yan Wu
- & Wei-Feng Chen
Laboratory Investigation 83 , 1185–1192

Rights & permissionsfor article HCA587 Antigen Expression in Normal Tissues and Cancers: Correlation with Tumor Differentiation in Hepatocellular Carcinoma . Opens in a new window.
Research | 1 February 2008
IL-10 Gene Modified Dendritic Cells Inhibit T Helper Type 1-Mediated Alloimmune Responses and Promote Immunological Tolerance in Diabetes
- Huifen Zhu
- , Wenhong Qiu
- , Ping Lei
- , Wei Zhou
- , Xue Wen
- , Fengrong He
- , Li Li
- , Hong Dai
- , Guanxin Shen
- & Feili Gong
Cellular & Molecular Immunology 5 , 41–46

Rights & permissionsfor article IL-10 Gene Modified Dendritic Cells Inhibit T Helper Type 1-Mediated Alloimmune Responses and Promote Immunological Tolerance in Diabetes . Opens in a new window.
Research | 5 September 2019
Oncogenic heterogeneous nuclear ribonucleoprotein D-like modulates the growth and imatinib response of human chronic myeloid leukemia CD34⁺ cells via pre-B-cell leukemia homeobox 1
- Dehuan Ji
- , Pengshan Zhang
- , Wenjuan Ma
- , Yiwen Fei
- , Wen Xue
- , Yu Wang
- , Xiuyan Zhang
- , Haixia Zhou
- & Yun Zhao
Oncogene 39 , 443–453

Rights & permissionsfor article Oncogenic heterogeneous nuclear ribonucleoprotein D-like modulates the growth and imatinib response of human chronic myeloid leukemia CD34<sup>+</sup> cells via pre-B-cell leukemia homeobox 1 . Opens in a new window.
Research | 21 August 2019 | Open
Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response
- Yi Yang
- , Thea L. Willis
- , Robert W. Button
- , Conor J. Strang
- , Yuhua Fu
- , Xue Wen
- , Portia R. C. Grayson
- , Tracey Evans
- , Rebecca J. Sipthorpe
- , Sheridan L. Roberts
- , Bing Hu
- , Jianke Zhang
- , Boxun Lu
- & Shouqing Luo
Nature Communications 10 , 1–18

Rights & permissionsfor article Cytoplasmic DAXX drives SQSTM1/p62 phase condensation to activate Nrf2-mediated stress response . Opens in a new window.
Research | 5 June 2019
Clcn3 deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice
- Ming-ming Ma
- , Chen-chen Jin
- , Xue-lian Huang
- , Lu Sun
- , Hui Zhou
- , Xue-jun Wen
- , Xiong-qing Huang
- , Jie-yi Du
- , Hong-shuo Sun
- , Zhu-xiao Ren
- , Jie Liu
- , Yong-yuan Guan
- , Xiao-miao Zhao
- & Guan-lei Wang
Acta Pharmacologica Sinica 40 , 1532–1543

Rights & permissionsfor article <i>Clcn3</i> deficiency ameliorates high-fat diet-induced obesity and adipose tissue macrophage inflammation in mice . Opens in a new window.
Reviews | 21 January 2019
CRISPR–Cas: a tool for cancer research and therapeutics
- Hao Yin
- , Wen Xue
- & Daniel G. Anderson
Nature Reviews Clinical Oncology 16 , 281–295

Rights & permissionsfor article CRISPR–Cas: a tool for cancer research and therapeutics . Opens in a new window.
Research | 3 December 2018
G3BP1 promotes DNA binding and activation of cGAS
- Zhao-Shan Liu
- , Hong Cai
- , Wen Xue
- , Miao Wang
- , Tian Xia
- , Wan-Jin Li
- , Jia-Qing Xing
- , Ming Zhao
- , Yi-Jiao Huang
- , Shuai Chen
- , Sheng-Ming Wu
- , Xinzheng Wang
- , Xin Liu
- , Xue Pang
- , Zi-Yu Zhang
- , Tingting Li
- , Jiang Dai
- , Fangting Dong
- , Qing Xia
- , Ai-Ling Li
- , Tao Zhou
- , Zheng-gang Liu
- , Xue-Min Zhang
- & Tao Li
Nature Immunology 20 , 18–28

Rights & permissionsfor article G3BP1 promotes DNA binding and activation of cGAS . Opens in a new window.
Research | 1 October 2018
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice
- Dan Wang
- , Jia Li
- , Chun-Qing Song
- , Karen Tran
- , Haiwei Mou
- , Pei-Hsuan Wu
- , Phillip W L Tai
- , Craig A Mendonca
- , Lingzhi Ren
- , Blake Y Wang
- , Qin Su
- , Dominic J Gessler
- , Phillip D Zamore
- , Wen Xue
- & Guangping Gao
Nature Biotechnology 36 , 839–842

Rights & permissionsfor article Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice . Opens in a new window.
Research | 29 January 2018
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
- Hao Yin
- , Chun-Qing Song
- , Sneha Suresh
- , Suet-Yan Kwan
- , Qiongqiong Wu
- , Stephen Walsh
- , Junmei Ding
- , Roman L Bogorad
- , Lihua Julie Zhu
- , Scot A Wolfe
- , Victor Koteliansky
- , Wen Xue
- , Robert Langer
- & Daniel G Anderson
Nature Chemical Biology 14 , 311–316

Rights & permissionsfor article Partial DNA-guided Cas9 enables genome editing with reduced off-target activity . Opens in a new window.
Research | 20 October 2017 | Open
PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum
- Guo-He Tan
- , Yuan-Yuan Liu
- , Lu Wang
- , Kui Li
- , Ze-Qiang Zhang
- , Hong-Fu Li
- , Zhong-Fei Yang
- , Yang Li
- , Dan Li
- , Ming-Yue Wu
- , Chun-Lei Yu
- , Juan-Juan Long
- , Ren-Chao Chen
- , Li-Xi Li
- , Lu-Ping Yin
- , Ji-Wei Liu
- , Xue-Wen Cheng
- , Qi Shen
- , You-Sheng Shu
- , Kenji Sakimura
- , Lu-Jian Liao
- , Zhi-Ying Wu
- & Zhi-Qi Xiong
Cell Research 28 , 90–110

Rights & permissionsfor article PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by regulating synaptic transmission in cerebellum . Opens in a new window.
Research | 13 October 2017 | Open
Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models
- Meng Yu
- , Yuhua Fu
- , Yijian Liang
- , Haikun Song
- , Yao Yao
- , Peng Wu
- , Yuwei Yao
- , Yuyin Pan
- , Xue Wen
- , Lixiang Ma
- , Saiyin Hexige
- , Yu Ding
- , Shouqing Luo
- & Boxun Lu
Cell Research 27 , 1441–1465

Rights & permissionsfor article Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models . Opens in a new window.
Research | 13 November 2017
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing
- Hao Yin
- , Chun-Qing Song
- , Sneha Suresh
- , Qiongqiong Wu
- , Stephen Walsh
- , Luke Hyunsik Rhym
- , Esther Mintzer
- , Mehmet Fatih Bolukbasi
- , Lihua Julie Zhu
- , Kevin Kauffman
- , Haiwei Mou
- , Alicia Oberholzer
- , Junmei Ding
- , Suet-Yan Kwan
- , Roman L Bogorad
- , Timofei Zatsepin
- , Victor Koteliansky
- , Scot A Wolfe
- , Wen Xue
- , Robert Langer
- & Daniel G Anderson
Nature Biotechnology 35 , 1179–1187

Rights & permissionsfor article Structure-guided chemical modification of guide RNA enables potent non-viral <i>in vivo</i> genome editing . Opens in a new window.
Research | 10 May 2017
A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
- Tuomas Tammela
- , Francisco J. Sanchez-Rivera
- , Naniye Malli Cetinbas
- , Katherine Wu
- , Nikhil S. Joshi
- , Katja Helenius
- , Yoona Park
- , Roxana Azimi
- , Natanya R. Kerper
- , R. Alexander Wesselhoeft
- , Xin Gu
- , Leah Schmidt
- , Milton Cornwall-Brady
- , Ömer H. Yilmaz
- , Wen Xue
- , Pekka Katajisto
- , Arjun Bhutkar
- & Tyler Jacks
Nature 545 , 355–359

Rights & permissionsfor article A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma . Opens in a new window.
Research | 29 May 2017
Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppressing the ROS/TLR4/NF-κB inflammatory signaling pathway
- Ni Pan
- , Liu-yi Lu
- , Mei Li
- , Guo-hao Wang
- , Fang-yun Sun
- , Hong-shuo Sun
- , Xue-jun Wen
- , Jian-ding Cheng
- , Jian-wen Chen
- , Ji-yan Pang
- , Jie Liu
- , Yong-yuan Guan
- , Li-yan Zhao
- , Wen-liang Chen
- & Guan-lei Wang
Acta Pharmacologica Sinica 38 , 1236–1247

Rights & permissionsfor article Xyloketal B alleviates cerebral infarction and neurologic deficits in a mouse stroke model by suppressing the ROS/TLR4/NF-κB inflammatory signaling pathway . Opens in a new window.
Research | 1 February 2016
Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo
- Hao Yin
- , Chun-Qing Song
- , Joseph R Dorkin
- , Lihua J Zhu
- , Yingxiang Li
- , Qiongqiong Wu
- , Angela Park
- , Junghoon Yang
- , Sneha Suresh
- , Aizhan Bizhanova
- , Ankit Gupta
- , Mehmet F Bolukbasi
- , Stephen Walsh
- , Roman L Bogorad
- , Guangping Gao
- , Zhiping Weng
- , Yizhou Dong
- , Victor Koteliansky
- , Scot A Wolfe
- , Robert Langer
- , Wen Xue
- & Daniel G Anderson
Nature Biotechnology 34 , 328–333

Rights & permissionsfor article Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components <i>in vivo</i> . Opens in a new window.
Research | 22 October 2014
Rapid modelling of cooperating genetic events in cancer through somatic genome editing
Nature 516 , 428–431

Rights & permissionsfor article Rapid modelling of cooperating genetic events in cancer through somatic genome editing . Opens in a new window.
Research | 6 August 2014
CRISPR-mediated direct mutation of cancer genes in the mouse liver
- Wen Xue
- , Sidi Chen
- , Hao Yin
- , Tuomas Tammela
- , Thales Papagiannakopoulos
- , Nikhil S. Joshi
- , Wenxin Cai
- , Gillian Yang
- , Roderick Bronson
- , Denise G. Crowley
- , Feng Zhang
- , Daniel G. Anderson
- , Phillip A. Sharp
- & Tyler Jacks
Nature 514 , 380–384

Rights & permissionsfor article CRISPR-mediated direct mutation of cancer genes in the mouse liver . Opens in a new window.
Research | 20 July 2015
Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma
- Lu Jiang
- , Zhao-Hui Gu
- , Zi-Xun Yan
- , Xia Zhao
- , Yin-Yin Xie
- , Zi-Guan Zhang
- , Chun-Ming Pan
- , Yuan Hu
- , Chang-Ping Cai
- , Ying Dong
- , Jin-Yan Huang
- , Li Wang
- , Yang Shen
- , Guoyu Meng
- , Jian-Feng Zhou
- , Jian-Da Hu
- , Jin-Fen Wang
- , Yuan-Hua Liu
- , Lin-Hua Yang
- , Feng Zhang
- , Jian-Min Wang
- , Zhao Wang
- , Zhi-Gang Peng
- , Fang-Yuan Chen
- , Zi-Min Sun
- , Hao Ding
- , Ju-Mei Shi
- , Jian Hou
- , Jin-Song Yan
- , Jing-Yi Shi
- , Lan Xu
- , Yang Li
- , Jing Lu
- , Zhong Zheng
- , Wen Xue
- , Wei-Li Zhao
- , Zhu Chen
- & Sai-Juan Chen
Nature Genetics 47 , 1061–1066

Rights & permissionsfor article Exome sequencing identifies somatic mutations of <i>DDX3X</i> in natural killer/T-cell lymphoma . Opens in a new window.
Research | 12 December 2014 | Open
Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans
- Xiang-Hong Xu
- , Xue-Wen Huang
- , Li Qun
- , Ya-Nan Li
- , Yi Wang
- , Chao Liu
- , Yanyun Ma
- , Qing-Mei Liu
- , Kang Sun
- , Feng Qian
- , Li Jin
- & Jiucun Wang
Scientific Reports 4 , 1–8

Rights & permissionsfor article Two functional loci in the promoter of <i>EPAS1</i> gene involved in high-altitude adaptation of Tibetans . Opens in a new window.
Research | 21 June 2011
Serum inducible kinase is a positive regulator of cortical dendrite development and is required for BDNF-promoted dendritic arborization
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Cell Research 22 , 387–398

Rights & permissionsfor article Serum inducible kinase is a positive regulator of cortical dendrite development and is required for BDNF-promoted dendritic arborization . Opens in a new window.
Research | 6 June 2007
A microRNA component of the p53 tumour suppressor network
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Nature 447 , 1130–1134

Rights & permissionsfor article A microRNA component of the p53 tumour suppressor network . Opens in a new window.
Research | 19 October 2008
IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis
- Mads Gyrd-Hansen
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Nature Cell Biology 10 , 1309–1317

Rights & permissionsfor article IAPs contain an evolutionarily conserved ubiquitin-binding domain that regulates NF-κB as well as cell survival and oncogenesis . Opens in a new window.

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