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Research | 18 June 2020
Identification of important genes and drug repurposing based on clinical-centered analysis across human cancers
- Ying Li
- , Ya-ping Dong
- , You-wen Qian
- , Le-xing Yu
- , Wen Wen
- , Xiu-liang Cui
- & Hong-yang Wang
Acta Pharmacologica Sinica , 1–8

Rights & permissionsfor article Identification of important genes and drug repurposing based on clinical-centered analysis across human cancers . Opens in a new window.
Research | 25 December 2018 | Open
A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating
- Yan-Xiang Ni
- , Nan Zhou
- , Wen-Qian Xue
- , Li Rong
- , Wing-Ho Yung
- , Rao-Zhou Lin
- , Richard Yi-Tsun Kao
- , Zhi-Gang Duan
- , Hai-Tao Sun
- , Hua-Rui Gong
- , Xu-Ming Tang
- , Meng-Fei Liu
- , Wen Zhang
- , Shuang Qi
- , Sookja Chung
- , You-Qiang Song
- & Jian-Dong Huang
Cell Discovery 4 , 1–13

Rights & permissionsfor article A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating . Opens in a new window.
Research | 10 August 2017 | Open
Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathway
- Ying Tan
- , Qiu-Meng Li
- , Ning Huang
- , Si Cheng
- , Guan-Jian Zhao
- , Hong Chen
- , Song Chen
- , Zhao-Hua Tang
- , Wen-Qian Zhang
- , Qin Huang
- & Yuan Cheng
Cell Death & Disease 8 , e2981–e2981

Rights & permissionsfor article Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathway . Opens in a new window.
Research | 14 September 2017
Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice
- Shou-cai Zhao
- , Chun Wang
- , Heng Xu
- , Wen-qian Wu
- , Zhao-hu Chu
- , Ling-song Ma
- , Ying-dong Zhang
- & Fudong Liu
Acta Pharmacologica Sinica 38 , 1425–1434

Rights & permissionsfor article Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice . Opens in a new window.
Research | 25 September 2020 | Open
DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl ¹H-NMR probe
- Qi Liu
- , Qing-tao He
- , Xiaoxuan Lyu
- , Fan Yang
- , Zhong-liang Zhu
- , Peng Xiao
- , Zhao Yang
- , Feng Zhang
- , Zhao-ya Yang
- , Xiao-yan Wang
- , Peng Sun
- , Qian-wen Wang
- , Chang-xiu Qu
- , Zheng Gong
- , Jing-yu Lin
- , Zhen Xu
- , Shao-le Song
- , Shen-ming Huang
- , Sheng-chao Guo
- , Ming-jie Han
- , Kong-kai Zhu
- , Xin Chen
- , Alem W. Kahsai
- , Kun-Hong Xiao
- , Wei Kong
- , Fa-hui Li
- , Ke Ruan
- , Zi-jian Li
- , Xiao Yu
- , Xiao-gang Niu
- , Chang-wen Jin
- , Jiangyun Wang
- & Jin-peng Sun
Nature Communications 11 , 1–17

Rights & permissionsfor article DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl 1H-NMR probe . Opens in a new window.
6 March 2017
Regulation of microglial activation in stroke
- Shou-cai Zhao
- , Ling-song Ma
- , Zhao-hu Chu
- , Heng Xu
- , Wen-qian Wu
- & Fudong Liu
Acta Pharmacologica Sinica 38 , 445–458

Rights & permissionsfor article Regulation of microglial activation in stroke . Opens in a new window.
Research | 5 January 2016 | Open
Morphine, a potential antagonist of cisplatin cytotoxicity, inhibits cisplatin-induced apoptosis and suppression of tumor growth in nasopharyngeal carcinoma xenografts
- Long-Hui Cao
- , Hui-Ting Li
- , Wen-Qian Lin
- , Hong-Ying Tan
- , Lan Xie
- , Zhong-Jian Zhong
- & Jian-Hua Zhou
Scientific Reports 6 , 1–10

Rights & permissionsfor article Morphine, a potential antagonist of cisplatin cytotoxicity, inhibits cisplatin-induced apoptosis and suppression of tumor growth in nasopharyngeal carcinoma xenografts . Opens in a new window.
Research | 2 May 2016
Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability
- Hui-yun Zhang
- , Caleb Kesse Firempong
- , Yuan-wen Wang
- , Wen-qian Xu
- , Miao-miao Wang
- , Xia Cao
- , Yuan Zhu
- , Shan-shan Tong
- , Jiang-nan Yu
- & Xi-ming Xu
Acta Pharmacologica Sinica 37 , 834–844

Rights & permissionsfor article Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability . Opens in a new window.
Research | 10 August 2015 | Open
Paclitaxel-induced lung injury and its amelioration by parecoxib sodium
- Wen-jie Liu
- , Zhong-jian Zhong
- , Long-hui Cao
- , Hui-ting Li
- , Tian-hua Zhang
- & Wen-qian Lin
Scientific Reports 5 , 1–9

Rights & permissionsfor article Paclitaxel-induced lung injury and its amelioration by parecoxib sodium . Opens in a new window.
Research | 10 August 2020
IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes
- Hao Zhou
- , Han Wang
- , Minjia Yu
- , Rebecca C. Schugar
- , Wen Qian
- , Fangqiang Tang
- , Weiwei Liu
- , Hui Yang
- , Ruth E. McDowell
- , Junjie Zhao
- , Ji Gao
- , Ashok Dongre
- , Julie A. Carman
- , Mei Yin
- , Judith A. Drazba
- , Robert Dent
- , Christopher Hine
- , Yeong-Renn Chen
- , Jonathan D. Smith
- , Paul L. Fox
- , J. Mark Brown
- & Xiaoxia Li
Nature Immunology 21 , 1219–1231

Rights & permissionsfor article IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes . Opens in a new window.
Research | 14 August 2020 | Open
Single cell electron collectors for highly efficient wiring-up electronic abiotic/biotic interfaces
- Yang-Yang Yu
- , Yan-Zhai Wang
- , Zhen Fang
- , Yu-Tong Shi
- , Qian-Wen Cheng
- , Yu-Xuan Chen
- , Weidong Shi
- & Yang-Chun Yong
Nature Communications 11 , 1–10

Rights & permissionsfor article Single cell electron collectors for highly efficient wiring-up electronic abiotic/biotic interfaces . Opens in a new window.
Research | 18 June 2019 | Open
Selection of suitable candidate genes for miRNA expression normalization in Yellow River Carp (Cyprinus carpio. var)
- Fang Wang
- , Qian-wen Yang
- , Wen-Jie Zhao
- , Qi-Yan Du
- & Zhong-Jie Chang
Scientific Reports 9 , 1–9

Rights & permissionsfor article Selection of suitable candidate genes for miRNA expression normalization in Yellow River Carp (Cyprinus carpio. var) . Opens in a new window.
Research | 18 April 2018 | Open
IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population
- Ling-Feng Zha
- , Shao-Fang Nie
- , Qian-Wen Chen
- , Yu-Hua Liao
- , Hong-Song Zhang
- , Jiang-Tao Dong
- , Tian Xie
- , Fan Wang
- , Ting-Ting Tang
- , Ni Xia
- , Cheng-Qi Xu
- , Ying-Chao Zhou
- , Zhi-Peng Zeng
- , Jiao Jiao
- , Peng-Yun Wang
- , Qing K. Wang
- , Xin Tu
- & Xiang Cheng
Scientific Reports 8 , 1–8

Rights & permissionsfor article IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population . Opens in a new window.
Research | 6 September 2016 | Open
Biogeography and Adaptive evolution of Streptomyces Strains from saline environments
- Fei Zhao
- , Yu-Hua Qin
- , Xin Zheng
- , Hong-Wei Zhao
- , Dong-Yan Chai
- , Wei Li
- , Ming-Xiang Pu
- , Xing-Sheng Zuo
- , Wen Qian
- , Ping Ni
- , Yong Zhang
- , Han Mei
- & Song-Tao He
Scientific Reports 6 , 1–9

Rights & permissionsfor article Biogeography and Adaptive evolution of Streptomyces Strains from saline environments . Opens in a new window.
16 September 2016
Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function
- Ping Lu
- , Fu-chuang Zhang
- , Shu-wen Qian
- , Xi Li
- , Zhao-meng Cui
- , Yong-jun Dang
- & Qi-qun Tang
Cell Research 26 , 1169–1172

Rights & permissionsfor article Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function . Opens in a new window.
Research | 14 April 2020 | Open
Elicitation of integrated immunity in mice by a novel pneumococcal polysaccharide vaccine conjugated with HBV surface antigen
- Wen Qian
- , Zhen Huang
- , Yuqiu Chen
- , Jinling Yang
- , Lili Wang
- , Kai Wu
- , Min Chen
- , Nanping Chen
- , Yongzhong Duan
- , Jing Shi
- , Ying Zhang
- & Qihan Li
Scientific Reports 10 , 1–12

Rights & permissionsfor article Elicitation of integrated immunity in mice by a novel pneumococcal polysaccharide vaccine conjugated with HBV surface antigen . Opens in a new window.
Research | 16 April 2013
Optical visualization of individual ultralong carbon nanotubes by chemical vapour deposition of titanium dioxide nanoparticles
- Rufan Zhang
- , Yingying Zhang
- , Qiang Zhang
- , Huanhuan Xie
- , Haidong Wang
- , Jingqi Nie
- , Qian Wen
- & Fei Wei
Nature Communications 4 , 1–7

Rights & permissionsfor article Optical visualization of individual ultralong carbon nanotubes by chemical vapour deposition of titanium dioxide nanoparticles . Opens in a new window.
1 January 2000
Angular change in backscattering of light from the human lens with nuclear cataract
- Wen Qian
Eye 14 , 56–60

Rights & permissionsfor article Angular change in backscattering of light from the human lens with nuclear cataract . Opens in a new window.
Research | 1 September 1994
Spatial distribution of back scattering in the nuclear area of the non-cataractous human lens
- Wen Qian
- , Per Söderberg
- , Bo Lindström
- , Enping Chen
- , Karin Magnius
- & Bo Philipson
Eye 8 , 524–529

Rights & permissionsfor article Spatial distribution of back scattering in the nuclear area of the non-cataractous human lens . Opens in a new window.
Research | 1 November 1993
A common lens nuclear area in Scheimpflug photographs
- Wen Qian
- , Per G Söderberg
- , Enping Chen
- , Karin Magnius
- & Bo Philipson
Eye 7 , 799–804

Rights & permissionsfor article A common lens nuclear area in Scheimpflug photographs . Opens in a new window.
Research | 1 April 2009
Analysis of the Conservation of T Cell Receptor Alpha and Beta Chain Variable Regions Gene in pp65 Peptide-Specific HLA-A^*0201-Restricted CD8⁺ T Cells
- Wei Luo
- , Li Ma
- , Qian Wen
- , Mingqian Zhou
- & Xiaoning Wang
Cellular & Molecular Immunology 6 , 105–110

Rights & permissionsfor article Analysis of the Conservation of T Cell Receptor Alpha and Beta Chain Variable Regions Gene in pp65 Peptide-Specific HLA-A*0201-Restricted CD8+ T Cells . Opens in a new window.
Research | 1 June 2008
A Modified Peptide Stimulation Method for Efficient Amplification of Cytomegalovirus (CMV)-Specific CTLs
- Guangping Ruan
- , Li Ma
- , Qian Wen
- , Wei Luo
- , Mingqian Zhou
- & Xiaoning Wang
Cellular & Molecular Immunology 5 , 197–201

Rights & permissionsfor article A Modified Peptide Stimulation Method for Efficient Amplification of Cytomegalovirus (CMV)-Specific CTLs . Opens in a new window.
Research | 2 October 2019 | Open
Rate-selected growth of ultrapure semiconducting carbon nanotube arrays
- Zhenxing Zhu
- , Nan Wei
- , Weijun Cheng
- , Boyuan Shen
- , Silei Sun
- , Jun Gao
- , Qian Wen
- , Rufan Zhang
- , Jun Xu
- , Yao Wang
- & Fei Wei
Nature Communications 10 , 1–8

Rights & permissionsfor article Rate-selected growth of ultrapure semiconducting carbon nanotube arrays . Opens in a new window.
Research | 25 July 2019 | Open
Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish
- Zhen Zhang
- , Chao Ran
- , Qian-wen Ding
- , Hong-liang Liu
- , Ming-xu Xie
- , Ya-lin Yang
- , Ya-dong Xie
- , Chen-chen Gao
- , Hong-ling Zhang
- & Zhi-gang Zhou
Communications Biology 2 , 1–17

Rights & permissionsfor article Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish . Opens in a new window.
Research | 21 March 2018
IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling
- Tomasz Herjan
- , Lingzi Hong
- , Jodi Bubenik
- , Katarzyna Bulek
- , Wen Qian
- , Caini Liu
- , Xiao Li
- , Xing Chen
- , Hui Yang
- , Suidong Ouyang
- , Hao Zhou
- , Junjie Zhao
- , Kommireddy Vasu
- , Eric Cockman
- , Mark Aronica
- , Kewal Asosingh
- , Donny D. Licatalosi
- , Jun Qin
- , Paul L. Fox
- , Thomas A. Hamilton
- , Donna Driscoll
- & Xiaoxia Li
Nature Immunology 19 , 354–365

Rights & permissionsfor article IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling . Opens in a new window.
Research | 17 April 2017
Wenshen Zhuanggu formula effectively suppresses breast cancer bone metastases in a mouse Xenograft model
- Jia-jia Li
- , Wei-ling Chen
- , Jian-yi Wang
- , Qian-wen Hu
- , Zhen-ping Sun
- , Shuai Zhang
- , Sheng Liu
- & Xiang-hui Han
Acta Pharmacologica Sinica 38 , 1369–1380

Rights & permissionsfor article Wenshen Zhuanggu formula effectively suppresses breast cancer bone metastases in a mouse Xenograft model . Opens in a new window.
Research | 20 April 2017 | Open
Glucocorticoids Suppress Antimicrobial Autophagy and Nitric Oxide Production and Facilitate Mycobacterial Survival in Macrophages
- Jinli Wang
- , Ruining Wang
- , Hui Wang
- , Xiaofan Yang
- , Jiahui Yang
- , Wenjing Xiong
- , Qian Wen
- & Li Ma
Scientific Reports 7 , 1–14

Rights & permissionsfor article Glucocorticoids Suppress Antimicrobial Autophagy and Nitric Oxide Production and Facilitate Mycobacterial Survival in Macrophages . Opens in a new window.
Research | 2 May 2016
Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway
- Yu Ji
- , Yan-nong Dou
- , Qian-wen Zhao
- , Ji-zhou Zhang
- , Yan Yang
- , Ting Wang
- , Yu-feng Xia
- , Yue Dai
- & Zhi-feng Wei
Acta Pharmacologica Sinica 37 , 794–804

Rights & permissionsfor article Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway . Opens in a new window.
Research | 14 December 2016 | Open
Microarray analysis of long noncoding RNA and mRNA expression profiles in human macrophages infected with Mycobacterium tuberculosis
- Xiaofan Yang
- , Jiahui Yang
- , Jinli Wang
- , Qian Wen
- , Hui Wang
- , Jianchun He
- , Shengfeng Hu
- , Wenting He
- , Xialin Du
- , Sudong Liu
- & Li Ma
Scientific Reports 6 , 1–12

Rights & permissionsfor article Microarray analysis of long noncoding RNA and mRNA expression profiles in human macrophages infected with Mycobacterium tuberculosis . Opens in a new window.
Research | 7 August 2011
The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation
- Katarzyna Bulek
- , Caini Liu
- , Shadi Swaidani
- , Liwen Wang
- , Richard C Page
- , Muhammet F Gulen
- , Tomasz Herjan
- , Amina Abbadi
- , Wen Qian
- , Dongxu Sun
- , Mark Lauer
- , Vincent Hascall
- , Saurav Misra
- , Mark R Chance
- , Mark Aronica
- , Thomas Hamilton
- & Xiaoxia Li
Nature Immunology 12 , 844–852

Rights & permissionsfor article The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation . Opens in a new window.
Research | 8 September 2009
p28^GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity
- Rong-Yang Dai
- , Yao Chen
- , Jing Fu
- , Li-Wei Dong
- , Yi-Bin Ren
- , Guang-Zhen Yang
- , You-Wen Qian
- , Jie Cao
- , Shan-Hua Tang
- , Sheng-Li Yang
- & Hong-Yang Wang
Cell Research 19 , 1243–1257

Rights & permissionsfor article p28GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity . Opens in a new window.
Research | 29 September 2009
Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death
- Shan Wang
- , Zhen Guo
- , Peng Xia
- , Tingting Liu
- , Jufang Wang
- , Shan Li
- , Lihua Sun
- , Jianxin Lu
- , Qian Wen
- , Mingqian Zhou
- , Li Ma
- , Xia Ding
- , Xiaoning Wang
- & Xuebiao Yao
Cell Research 19 , 1350–1362

Rights & permissionsfor article Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death . Opens in a new window.
5 March 2012
Activation of transient receptor potential vanilloid subtype 1 increases expression and permeability of tight junction in normal and hyposecretory submandibular gland
- Xin Cong
- , Yan Zhang
- , Liang Shi
- , Ning-Yan Yang
- , Chong Ding
- , Jing Li
- , Qian-Wen Ding
- , Yun-Chao Su
- , Ruo-Lan Xiang
- , Li-Ling Wu
- & Guang-Yan Yu
Laboratory Investigation 92 , 753–768

Rights & permissionsfor article Activation of transient receptor potential vanilloid subtype 1 increases expression and permeability of tight junction in normal and hyposecretory submandibular gland . Opens in a new window.

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Identification of important genes and drug repurposing based on clinical-centered analysis across human cancers

A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating

Upregulation of DACT2 suppresses proliferation and enhances apoptosis of glioma cell via inactivation of YAP signaling pathway

Age-related differences in interferon regulatory factor-4 and -5 signaling in ischemic brains of mice

DeSiphering receptor core-induced and ligand-dependent conformational changes in arrestin via genetic encoded trimethylsilyl ¹H-NMR probe

Regulation of microglial activation in stroke

Morphine, a potential antagonist of cisplatin cytotoxicity, inhibits cisplatin-induced apoptosis and suppression of tumor growth in nasopharyngeal carcinoma xenografts

Ergosterol-loaded poly(lactide-co-glycolide) nanoparticles with enhanced in vitro antitumor activity and oral bioavailability

Paclitaxel-induced lung injury and its amelioration by parecoxib sodium

IL-1 induces mitochondrial translocation of IRAK2 to suppress oxidative metabolism in adipocytes

Single cell electron collectors for highly efficient wiring-up electronic abiotic/biotic interfaces

Selection of suitable candidate genes for miRNA expression normalization in Yellow River Carp (Cyprinus carpio. var)

IL-13 may be involved in the development of CAD via different mechanisms under different conditions in a Chinese Han population

Biogeography and Adaptive evolution of Streptomyces Strains from saline environments

Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function

Elicitation of integrated immunity in mice by a novel pneumococcal polysaccharide vaccine conjugated with HBV surface antigen

Optical visualization of individual ultralong carbon nanotubes by chemical vapour deposition of titanium dioxide nanoparticles

Angular change in backscattering of light from the human lens with nuclear cataract

Spatial distribution of back scattering in the nuclear area of the non-cataractous human lens

A common lens nuclear area in Scheimpflug photographs

Analysis of the Conservation of T Cell Receptor Alpha and Beta Chain Variable Regions Gene in pp65 Peptide-Specific HLA-A^*0201-Restricted CD8⁺ T Cells

A Modified Peptide Stimulation Method for Efficient Amplification of Cytomegalovirus (CMV)-Specific CTLs

Rate-selected growth of ultrapure semiconducting carbon nanotube arrays

Ability of prebiotic polysaccharides to activate a HIF1α-antimicrobial peptide axis determines liver injury risk in zebrafish

IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling

Wenshen Zhuanggu formula effectively suppresses breast cancer bone metastases in a mouse Xenograft model

Glucocorticoids Suppress Antimicrobial Autophagy and Nitric Oxide Production and Facilitate Mycobacterial Survival in Macrophages

Paeoniflorin suppresses TGF-β mediated epithelial-mesenchymal transition in pulmonary fibrosis through a Smad-dependent pathway

Microarray analysis of long noncoding RNA and mRNA expression profiles in human macrophages infected with Mycobacterium tuberculosis

The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation

p28^GANK inhibits endoplasmic reticulum stress-induced cell death via enhancement of the endoplasmic reticulum adaptive capacity

Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death

Activation of transient receptor potential vanilloid subtype 1 increases expression and permeability of tight junction in normal and hyposecretory submandibular gland

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