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Research | 16 December 2020 | Open
Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer
- Baijun Dong
- , Juju Miao
- , Yanqing Wang
- , Wenqin Luo
- , Zhongzhong Ji
- , Huadong Lai
- , Man Zhang
- , Xiaomu Cheng
- , Jinming Wang
- , Yuxiang Fang
- , Helen He Zhu
- , Chee Wai Chua
- , Liancheng Fan
- , Yinjie Zhu
- , Jiahua Pan
- , Jia Wang
- , Wei Xue
- & Wei-Qiang Gao
Communications Biology 3 , 1–15

Rights & permissionsfor article Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer . Opens in a new window.
Research | 11 March 2020
Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel–Lindau protein
- Hanyu Rao
- , Xuefeng Li
- , Min Liu
- , Jing Liu
- , Xiaoxue Li
- , Jin Xu
- , Li Li
- & Wei-Qiang Gao
Oncogene 39 , 3853–3866

Rights & permissionsfor article Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel–Lindau protein . Opens in a new window.
Research | 4 November 2015 | Open
Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer
- Shengzhe Zhang
- , Ying Jing
- , Meiying Zhang
- , Zhenfeng Zhang
- , Pengfei Ma
- , Huixin Peng
- , Kaixuan Shi
- , Wei-Qiang Gao
- & Guanglei Zhuang
Scientific Reports 5 , 1–10

Rights & permissionsfor article Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer . Opens in a new window.
Research | 5 February 2020 | Open
Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate
- Xue Wang
- , Haibo Xu
- , Chaping Cheng
- , Zhongzhong Ji
- , Huifang Zhao
- , Yaru Sheng
- , Xiaoxia Li
- , Jinming Wang
- , Yu Shu
- , Yuman He
- , Liancheng Fan
- , Baijun Dong
- , Wei Xue
- , Chee Wai Chua
- , Dongdong Wu
- , Wei-Qiang Gao
- & Helen He Zhu
Nature Communications 11 , 1–16

Rights & permissionsfor article Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate . Opens in a new window.
Research | 1 June 2000
Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
- J. Lisa Zheng
- & Wei-Qiang Gao
Nature Neuroscience 3 , 580–586

Rights & permissionsfor article Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears . Opens in a new window.
Research | 10 October 2019 | Open
BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration
- Min Liu
- , Tongyu Sun
- , Ni Li
- , Junjie Peng
- , Da Fu
- , Wei Li
- , Li Li
- & Wei-Qiang Gao
Nature Communications 10 , 1–15

Rights & permissionsfor article BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration . Opens in a new window.
Research | 17 September 2019
Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling
- Minglei Wang
- , Wenqin Luo
- , Yu Zhang
- , Rong Yang
- , Xuefeng Li
- , Yanjing Guo
- , Chenlu Zhang
- , Ru Yang
- & Wei-Qiang Gao
Cell Death and Differentiation 27 , 1286–1299

Rights & permissionsfor article Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling . Opens in a new window.
Research | 26 July 2019 | Open
The histone methyltransferase Setd2 is indispensable for V(D)J recombination
- Zhongzhong Ji
- , Yaru Sheng
- , Juju Miao
- , Xiaoxia Li
- , Huifang Zhao
- , Jinming Wang
- , Chaping Cheng
- , Xue Wang
- , Kaiyuan Liu
- , Kai Zhang
- , Longmei Xu
- , Jufang Yao
- , Lijing Shen
- , Jian Hou
- , Wenhao Zhou
- , Jinqiao Sun
- , Li Li
- , Wei-Qiang Gao
- & Helen He Zhu
Nature Communications 10 , 1–13

Rights & permissionsfor article The histone methyltransferase Setd2 is indispensable for V(D)J recombination . Opens in a new window.
Research | 11 March 2019
Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex
- Jie Liu
- , Yanfeng Liu
- , Jiaxiang Shao
- , Yisheng Li
- , Lixia Qin
- , Hailian Shen
- , Yunli Xie
- , Weiliang Xia
- & Wei-Qiang Gao
Cell Death and Differentiation 26 , 2479–2492

Rights & permissionsfor article Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex . Opens in a new window.
Research | 22 November 2018
Loss of Par3 promotes prostatic tumorigenesis by enhancing cell growth and changing cell division modes
- Pei-Jie Zhou
- , Xiao Wang
- , Na An
- , Lianzi Wei
- , Long Zhang
- , Xingxu Huang
- , Helen He Zhu
- , Yu-Xiang Fang
- & Wei-Qiang Gao
Oncogene 38 , 2192–2205

Rights & permissionsfor article Loss of Par3 promotes prostatic tumorigenesis by enhancing cell growth and changing cell division modes . Opens in a new window.
Research | 8 October 2018
Elimination of CD4^lowHLA-G⁺ T cells overcomes castration-resistance in prostate cancer therapy
- Chao Wang
- , Jiahuan Chen
- , Qianfei Zhang
- , Wang Li
- , Shengbo Zhang
- , Yanjie Xu
- , Fang Wang
- , Bing Zhang
- , Yan Zhang
- & Wei-Qiang Gao
Cell Research 28 , 1103–1117

Rights & permissionsfor article Elimination of CD4lowHLA-G+ T cells overcomes castration-resistance in prostate cancer therapy . Opens in a new window.
Research | 10 July 2018 | Open
CCL5-deficiency enhances intratumoral infiltration of CD8⁺ T cells in colorectal cancer
- Shengbo Zhang
- , Ming Zhong
- , Chao Wang
- , Yanjie Xu
- , Wei-Qiang Gao
- & Yan Zhang
Cell Death & Disease 9 , 1–15

Rights & permissionsfor article CCL5-deficiency enhances intratumoral infiltration of CD8+ T cells in colorectal cancer . Opens in a new window.
Research | 5 January 2018 | Open
Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system
- Min Sun
- , Qingqing Yuan
- , Minghui Niu
- , Hong Wang
- , Liping Wen
- , Chencheng Yao
- , Jingmei Hou
- , Zheng Chen
- , Hongyong Fu
- , Fan Zhou
- , Chong Li
- , Shaorong Gao
- , Wei-Qiang Gao
- , Zheng Li
- & Zuping He
Cell Death and Differentiation 25 , 749–766

Rights & permissionsfor article Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system . Opens in a new window.
Research | 13 November 2017 | Open
TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma
- Deguan Lv
- , Yanxin Li
- , Weiwei Zhang
- , Angel A. Alvarez
- , Lina Song
- , Jianming Tang
- , Wei-Qiang Gao
- , Bo Hu
- , Shi-Yuan Cheng
- & Haizhong Feng
Nature Communications 8 , 1–13

Rights & permissionsfor article TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma . Opens in a new window.
Research | 10 October 2017 | Open
Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer
- Pengfei Ma
- , Yujie Fu
- , Mei-Chun Cai
- , Ying Yan
- , Ying Jing
- , Shengzhe Zhang
- , Minjiang Chen
- , Jie Wu
- , Ying Shen
- , Liang Zhu
- , Hong-Zhuan Chen
- , Wei-Qiang Gao
- , Mengzhao Wang
- , Zhenyu Gu
- , Trever G. Bivona
- , Xiaojing Zhao
- & Guanglei Zhuang
Nature Communications 8 , 1–11

Rights & permissionsfor article Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer . Opens in a new window.
26 August 2016
Stox1 as a novel transcriptional suppressor of Math1 during cerebellar granule neurogenesis and medulloblastoma formation
- Chenlu Zhang
- , Zhongzhong Ji
- , Minglei Wang
- , Weiwei Zhang
- , Rong Yang
- , Huanping An
- , Ru Yang
- , Daan van Abel
- , Marie van Dijk
- , Xiaohang Yang
- , Guangshuo Ou
- , Helen He Zhu
- & Wei-Qiang Gao
Cell Death and Differentiation 23 , 2042–2053

Rights & permissionsfor article Stox1 as a novel transcriptional suppressor of Math1 during cerebellar granule neurogenesis and medulloblastoma formation . Opens in a new window.
Research | 28 August 2014
Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages
- Jia Wang
- , Helen He Zhu
- , Mingliang Chu
- , Yunying Liu
- , Chenxi Zhang
- , Geng Liu
- , Xiaohang Yang
- , Ru Yang
- & Wei-Qiang Gao
Nature Communications 5 , 1–13

Rights & permissionsfor article Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages . Opens in a new window.
Research | 2 February 2015 | Open
Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway
- Yizhou Quan
- , Li Xia
- , Jiaxiang Shao
- , Shankai Yin
- , C. Yan Cheng
- , Weiliang Xia
- & Wei-Qiang Gao
Scientific Reports 5 , 1–10

Rights & permissionsfor article Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway . Opens in a new window.
Research | 29 May 2015
Park7 interacts with p47^phox to direct NADPH oxidase-dependent ROS production and protect against sepsis
- Wenjun Liu
- , Hailong Wu
- , Lili Chen
- , Yankai Wen
- , Xiaoni Kong
- & Wei-Qiang Gao
Cell Research 25 , 691–706

Rights & permissionsfor article Park7 interacts with p47phox to direct NADPH oxidase-dependent ROS production and protect against sepsis . Opens in a new window.
Research | 22 October 2008
Generation of a prostate from a single adult stem cell
- Kevin G. Leong
- , Bu-Er Wang
- , Leisa Johnson
- & Wei-Qiang Gao
Nature 456 , 804–808

Rights & permissionsfor article Generation of a prostate from a single adult stem cell . Opens in a new window.
Research | 15 May 2011
COP1 is a tumour suppressor that causes degradation of ETS transcription factors
- Alberto C. Vitari
- , Kevin G. Leong
- , Kim Newton
- , Cindy Yee
- , Karen O’Rourke
- , Jinfeng Liu
- , Lilian Phu
- , Rajesh Vij
- , Ronald Ferrando
- , Suzana S. Couto
- , Sankar Mohan
- , Ajay Pandita
- , Jo-Anne Hongo
- , David Arnott
- , Ingrid E. Wertz
- , Wei-Qiang Gao
- , Dorothy M. French
- & Vishva M. Dixit
Nature 474 , 403–406

Rights & permissionsfor article COP1 is a tumour suppressor that causes degradation of ETS transcription factors . Opens in a new window.

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Single-cell analysis supports a luminal-neuroendocrine transdifferentiation in human prostate cancer

Di-Ras2 promotes renal cell carcinoma formation by activating the mitogen-activated protein kinase pathway in the absence of von Hippel–Lindau protein

Stroma-associated master regulators of molecular subtypes predict patient prognosis in ovarian cancer

Identification of a Zeb1 expressing basal stem cell subpopulation in the prostate

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

BRG1 attenuates colonic inflammation and tumorigenesis through autophagy-dependent oxidative stress sequestration

Trim32 suppresses cerebellar development and tumorigenesis by degrading Gli1/sonic hedgehog signaling

The histone methyltransferase Setd2 is indispensable for V(D)J recombination

Zeb1 is important for proper cleavage plane orientation of dividing progenitors and neuronal migration in the mouse neocortex

Loss of Par3 promotes prostatic tumorigenesis by enhancing cell growth and changing cell division modes

Elimination of CD4^lowHLA-G⁺ T cells overcomes castration-resistance in prostate cancer therapy

CCL5-deficiency enhances intratumoral infiltration of CD8⁺ T cells in colorectal cancer

Efficient generation of functional haploid spermatids from human germline stem cells by three-dimensional-induced system

TRIM24 is an oncogenic transcriptional co-activator of STAT3 in glioblastoma

Simultaneous evolutionary expansion and constraint of genomic heterogeneity in multifocal lung cancer

Stox1 as a novel transcriptional suppressor of Math1 during cerebellar granule neurogenesis and medulloblastoma formation

Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages

Adjudin protects rodent cochlear hair cells against gentamicin ototoxicity via the SIRT3-ROS pathway

Park7 interacts with p47^phox to direct NADPH oxidase-dependent ROS production and protect against sepsis

Generation of a prostate from a single adult stem cell

COP1 is a tumour suppressor that causes degradation of ETS transcription factors

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