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Research | 1 December 2020 | Open
Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects
- tero.aittokallio@helsinki.fi
- Heli Julkunen
- , Anna Cichonska
- , Prson Gautam
- , Sandor Szedmak
- , Jane Douat
- , Tapio Pahikkala
- , Tero Aittokallio
- & Juho Rousu
Nature Communications 11 , 1–11

Rights & permissionsfor article Leveraging multi-way interactions for systematic prediction of pre-clinical drug combination effects . Opens in a new window.
Research | 23 January 2020 | Open
A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening
- tero.aittokallio@helsinki.fi
Communications Biology 3 , 1–12

Rights & permissionsfor article A normalized drug response metric improves accuracy and consistency of anticancer drug sensitivity quantification in cell-based screening . Opens in a new window.
Research | 9 December 2019
Prediction of drug combination effects with a minimal set of experiments
- tero.aittokallio@helsinki.fi
- Aleksandr Ianevski
- , Anil K. Giri
- , Prson Gautam
- , Alexander Kononov
- , Swapnil Potdar
- , Jani Saarela
- , Krister Wennerberg
- & Tero Aittokallio
Nature Machine Intelligence 1 , 568–577

Rights & permissionsfor article Prediction of drug combination effects with a minimal set of experiments . Opens in a new window.
Research | 30 November 2016
Consistency in drug response profiling
- tero.aittokallio@fimm.fi
- John Patrick Mpindi
- , Bhagwan Yadav
- , Päivi Östling
- , Prson Gautam
- , Disha Malani
- , Astrid Murumägi
- , Akira Hirasawa
- , Sara Kangaspeska
- , Krister Wennerberg
- , Olli Kallioniemi
- & Tero Aittokallio
Nature 540 , E5–E6

Rights & permissionsfor article Consistency in drug response profiling . Opens in a new window.
Research | 8 July 2019 | Open
Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer
- tero.aittokallio@helsinki.fi
- Jing Tang
- , Prson Gautam
- , Abhishekh Gupta
- , Liye He
- , Sanna Timonen
- , Yevhen Akimov
- , Wenyu Wang
- , Agnieszka Szwajda
- , Alok Jaiswal
- , Denes Turei
- , Bhagwan Yadav
- , Matti Kankainen
- , Jani Saarela
- , Julio Saez-Rodriguez
- , Krister Wennerberg
- & Tero Aittokallio
npj Systems Biology and Applications 5 , 1–11

Rights & permissionsfor article Network pharmacology modeling identifies synergistic Aurora B and ZAK interaction in triple-negative breast cancer . Opens in a new window.
Research | 28 August 2020 | Open
A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions
- tero.aittokallio@fimm.fi
- Michael Gabriel
- , Vidal Fey
- , Taija Heinosalo
- , Prem Adhikari
- , Kalle Rytkönen
- , Tuomo Komulainen
- , Kaisa Huhtinen
- , Teemu Daniel Laajala
- , Harri Siitari
- , Arho Virkki
- , Pia Suvitie
- , Harry Kujari
- , Tero Aittokallio
- , Antti Perheentupa
- & Matti Poutanen
Scientific Data 7 , 1–13

Rights & permissionsfor article A relational database to identify differentially expressed genes in the endometrium and endometriosis lesions . Opens in a new window.
Research | 2 August 2016 | Open
Optimized design and analysis of preclinical intervention studies in vivo
- tero.aittokallio@fimm.fi
- Teemu D. Laajala
- , Mikael Jumppanen
- , Riikka Huhtaniemi
- , Vidal Fey
- , Amanpreet Kaur
- , Matias Knuuttila
- , Eija Aho
- , Riikka Oksala
- , Jukka Westermarck
- , Sari Mäkelä
- , Matti Poutanen
- & Tero Aittokallio
Scientific Reports 6 , 1–13

Rights & permissionsfor article Optimized design and analysis of preclinical intervention studies <i>in vivo</i> . Opens in a new window.
Research | 5 June 2014 | Open
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
- tero.aittokallio@fimm.fi
- Bhagwan Yadav
- , Tea Pemovska
- , Agnieszka Szwajda
- , Evgeny Kulesskiy
- , Mika Kontro
- , Riikka Karjalainen
- , Muntasir Mamun Majumder
- , Disha Malani
- , Astrid Murumägi
- , Jonathan Knowles
- , Kimmo Porkka
- , Caroline Heckman
- , Olli Kallioniemi
- , Krister Wennerberg
- & Tero Aittokallio
Scientific Reports 4 , 1–10

Rights & permissionsfor article Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies . Opens in a new window.

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