nature.com search

Loading Filters

Showing 1–41 of 41 results

Loading Filters

Amendments and Corrections | 15 January 2019 | Open
Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation
- Jr-Ming Yang
- , Sayak Bhattacharya
- , Hoku West-Foyle
- , Chien-Fu Hung
- , T.-C. Wu
- , Pablo A. Iglesias
- & Chuan-Hsiang Huang
Nature Communications 10 , 1–1

Rights & permissionsfor article Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation . Opens in a new window.
Amendments and Corrections | 15 January 2019 | Open
Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation
- Jr-Ming Yang
- , Sayak Bhattacharya
- , Hoku West-Foyle
- , Chien-Fu Hung
- , T.-C. Wu
- , Pablo A. Iglesias
- & Chuan-Hsiang Huang
Nature Communications 10 , 1–1

Rights & permissionsfor article Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation . Opens in a new window.
Amendments and Corrections | 17 July 2017
Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
- D-W Wu
- , M-C Lee
- , N-Y Hsu
- , T-C Wu
- , J-Y Wu
- , Y-C Wang
- , Y-W Cheng
- , C-Y Chen
- & H Lee
Oncogene 36 , 5439–5439

Rights & permissionsfor article Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction . Opens in a new window.
Amendments and Corrections | 7 May 2015
Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
- D-W Wu
- , M-C Lee
- , N-Y Hsu
- , T-C Wu
- , J-Y Wu
- , Y-C Wang
- , Y-W Cheng
- , C-Y Chen
- & H Lee
Oncogene 34 , 2546–2546

Rights & permissionsfor article Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction . Opens in a new window.
Amendments and Corrections | 15 April 2008
Erratum: Role of IL-2 secreted by PADRE-specific CD4+ T cells in enhancing E7-specific CD8+ T-cell immune responses
- D Kim
- , A Monie
- , L He
- , Y-C Tsai
- , C-F Hung
- & T-C Wu
Gene Therapy 15 , 702–702

Rights & permissionsfor article Erratum: Role of IL-2 secreted by PADRE-specific CD4+ T cells in enhancing E7-specific CD8+ T-cell immune responses . Opens in a new window.
Amendments and Corrections | 16 July 2015
Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
- D-W Wu
- , M-C Lee
- , N-Y Hsu
- , T-C Wu
- , J-Y Wu
- , Y-C Wang
- , Y-W Cheng
- , C-Y Chen
- & H Lee
Oncogene 34 , 3882–3883

Rights & permissionsfor article Erratum: FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction . Opens in a new window.
26 February 2004
Comparison of HPV DNA vaccines employing intracellular targeting strategies
- J W Kim
- , C-F Hung
- , J Juang
- , L He
- , T Woo Kim
- , D K Armstrong
- , S I Pai
- , P-J Chen
- , C-T Lin
- , D A Boyd
- & T-C Wu
Gene Therapy 11 , 1011–1018

Rights & permissionsfor article Comparison of HPV DNA vaccines employing intracellular targeting strategies . Opens in a new window.
28 July 2008
CD8⁺ T cells, NK cells and IFN-γ are important for control of tumor with downregulated MHC class I expression by DNA vaccination
- W F Cheng
- , C F Hung
- , K Y Lin
- , M Ling
- , J Juang
- , L He
- , C T Lin
- & T-C Wu
Gene Therapy 10 , 1311–1320

Rights & permissionsfor article CD8<sup>+</sup> T cells, NK cells and IFN-γ are important for control of tumor with downregulated MHC class I expression by DNA vaccination . Opens in a new window.
Research | 18 August 2005
Characterization of HLA-A2-restricted HPV-16 E7-specific CD8⁺ T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice
- S Peng
- , C Trimble
- , L He
- , Y-C Tsai
- , C-T Lin
- , D A K Boyd
- , D Pardoll
- , C-F Hung
- & T-C Wu
Gene Therapy 13 , 67–77

Rights & permissionsfor article Characterization of HLA-A2-restricted HPV-16 E7-specific CD8<sup>+</sup> T-cell immune responses induced by DNA vaccines in HLA-A2 transgenic mice . Opens in a new window.
Research | 11 May 2017
Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation
- Y Sun
- , S Peng
- , A Yang
- , E Farmer
- , T-C Wu
- & C-F Hung
Gene Therapy 24 , 408–415

Rights & permissionsfor article Coinjection of IL2 DNA enhances E7-specific antitumor immunity elicited by intravaginal therapeutic HPV DNA vaccination with electroporation . Opens in a new window.
Research | 19 March 2015 | Open
Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors
- Y Sun
- , S Peng
- , J Qiu
- , J Miao
- , B Yang
- , J Jeang
- , C-F Hung
- & T-C Wu
Gene Therapy 22 , 528–535

Rights & permissionsfor article Intravaginal HPV DNA vaccination with electroporation induces local CD8+ T-cell immune responses and antitumor effects against cervicovaginal tumors . Opens in a new window.
Research | 4 November 2014 | Open
The Dynamic Dielectric at a Brain Functional Site and an EM Wave Approach to Functional Brain Imaging
- X. P. Li
- , Q. Xia
- , D. Qu
- , T. C. Wu
- , D. G. Yang
- , W. D. Hao
- , X. Jiang
- & X. M. Li
Scientific Reports 4 , 1–6

Rights & permissionsfor article The Dynamic Dielectric at a Brain Functional Site and an EM Wave Approach to Functional Brain Imaging . Opens in a new window.
Research | 21 June 2007
Control of human mesothelin-expressing tumors by DNA vaccines
- C-L Chang
- , T-C Wu
- & C-F Hung
Gene Therapy 14 , 1189–1198

Rights & permissionsfor article Control of human mesothelin-expressing tumors by DNA vaccines . Opens in a new window.
Research | 14 February 2008
Role of IL-2 secreted by PADRE-specific CD4⁺ T cells in enhancing E7-specific CD8⁺ T-cell immune responses
- D Kim
- , A Monie
- , L He
- , Y-C Tsai
- , C-F Hung
- & T-C Wu
Gene Therapy 15 , 677–687

Rights & permissionsfor article Role of IL-2 secreted by PADRE-specific CD4<sup>+</sup> T cells in enhancing E7-specific CD8<sup>+</sup> T-cell immune responses . Opens in a new window.
5 January 2000
Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs
- C-H Chen
- , H Ji
- , K W Suh
- , M A Choti
- , D M Pardoll
- & T-C Wu
Gene Therapy 6 , 1972–1981

Rights & permissionsfor article Gene gun-mediated DNA vaccination induces antitumor immunity against human papillomavirus type 16 E7-expressing murine tumor metastases in the liver and lungs . Opens in a new window.
Research | 10 April 2008
Cluster intradermal DNA vaccination rapidly induces E7-specific CD8⁺ T-cell immune responses leading to therapeutic antitumor effects
- S Peng
- , C Trimble
- , R D Alvarez
- , W K Huh
- , Z Lin
- , A Monie
- , C-F Hung
- & T-C Wu
Gene Therapy 15 , 1156–1166

Rights & permissionsfor article Cluster intradermal DNA vaccination rapidly induces E7-specific CD8<sup>+</sup> T-cell immune responses leading to therapeutic antitumor effects . Opens in a new window.
31 March 2005
Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope
- C-H Huang
- , S Peng
- , L He
- , Y-C Tsai
- , D A K Boyd
- , T H Hansen
- , T-C Wu
- & C-F Hung
Gene Therapy 12 , 1180–1186

Rights & permissionsfor article Cancer immunotherapy using a DNA vaccine encoding a single-chain trimer of MHC class I linked to an HPV-16 E6 immunodominant CTL epitope . Opens in a new window.
15 May 2000
Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity
- T-L Wang
- , M Ling
- , I-M Shih
- , T Pham
- , S I Pai
- , Z Lu
- , R J Kurman
- , D M Pardoll
- & T-C Wu
Gene Therapy 7 , 726–733

Rights & permissionsfor article Intramuscular administration of E7-transfected dendritic cells generates the most potent E7-specific anti-tumor immunity . Opens in a new window.
18 April 2001
Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen
- K-F Hsu
- , C-F Hung
- , W-F Cheng
- , L He
- , LA Slater
- , M Ling
- & T-C Wu
Gene Therapy 8 , 376–383

Rights & permissionsfor article Enhancement of suicidal DNA vaccine potency by linking Mycobacterium tuberculosis heat shock protein 70 to an antigen . Opens in a new window.
Research | 5 August 2010
Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients
- Y-T Kao
- , C-C Huang
- , H-B Leu
- , T-C Wu
- , P-H Huang
- , S-J Lin
- & J-W Chen
Journal of Human Hypertension 25 , 444–450

Rights & permissionsfor article Ambulatory pulse pressure as a novel predictor for long-term prognosis in essential hypertensive patients . Opens in a new window.
Research | 19 June 2005
A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression
- Adriaan D Bins
- , Annelies Jorritsma
- , Monika C Wolkers
- , Chien-Fu Hung
- , T-C Wu
- , Ton N M Schumacher
- & John B A G Haanen
Nature Medicine 11 , 899–904

Rights & permissionsfor article A rapid and potent DNA vaccination strategy defined by <i>in vivo</i> monitoring of antigen expression . Opens in a new window.
Research | 8 May 2008
Enhancement of CD4⁺ T-cell help reverses the doxorubicin-induced suppression of antigen-specific immune responses in vaccinated mice
- D Kim
- , A Monie
- , Y-C Tsai
- , L He
- , M-C Wang
- , C-F Hung
- & T-C Wu
Gene Therapy 15 , 1176–1183

Rights & permissionsfor article Enhancement of CD4<sup>+</sup> T-cell help reverses the doxorubicin-induced suppression of antigen-specific immune responses in vaccinated mice . Opens in a new window.
Research | 17 August 2006
Vaccinia virus preferentially infects and controls human and murine ovarian tumors in mice
- C-F Hung
- , Y-C Tsai
- , L He
- , G Coukos
- , I Fodor
- , L Qin
- , H Levitsky
- & T-C Wu
Gene Therapy 14 , 20–29

Rights & permissionsfor article Vaccinia virus preferentially infects and controls human and murine ovarian tumors in mice . Opens in a new window.
Research | 22 March 2007
Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8⁺ T cells
- C-F Hung
- , Y-C Tsai
- , L He
- & T-C Wu
Gene Therapy 14 , 921–929

Rights & permissionsfor article Control of mesothelin-expressing ovarian cancer using adoptive transfer of mesothelin peptide-specific CD8<sup>+</sup> T cells . Opens in a new window.
Research | 26 November 2009
Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA
- T H Kang
- , J-Y Chung
- , A Monie
- , S I Pai
- , C-F Hung
- & T-C Wu
Gene Therapy 17 , 531–540

Rights & permissionsfor article Enhancing DNA vaccine potency by co-administration of xenogenic MHC class-I DNA . Opens in a new window.
22 January 2004
Enhancement of suicidal DNA vaccine potency by delaying suicidal DNA-induced cell death
- TW Kim
- , C-F Hung
- , J Juang
- , L He
- , JM Hardwick
- & T-C Wu
Gene Therapy 11 , 336–342

Rights & permissionsfor article Enhancement of suicidal DNA vaccine potency by delaying suicidal DNA-induced cell death . Opens in a new window.
Research | 28 February 2008
Clinical predictors of the response to short-term thiazide treatment in nondiabetic essential hypertensives
- C-C Huang
- , H-B Leu
- , T-C Wu
- , S-J Lin
- & J-W Chen
Journal of Human Hypertension 22 , 329–337

Rights & permissionsfor article Clinical predictors of the response to short-term thiazide treatment in nondiabetic essential hypertensives . Opens in a new window.
Research | 22 September 2005
A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects
- S Peng
- , T T Tomson
- , C Trimble
- , L He
- , C-F Hung
- & T-C Wu
Gene Therapy 13 , 257–265

Rights & permissionsfor article A combination of DNA vaccines targeting human papillomavirus type 16 E6 and E7 generates potent antitumor effects . Opens in a new window.
Research | 7 November 2018 | Open
Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation
- Jr-Ming Yang
- , Sayak Bhattacharya
- , Hoku West-Foyle
- , Chien-Fu Hung
- , T.-C. Wu
- , Pablo A. Iglesias
- & Chuan-Hsiang Huang
Nature Communications 9 , 1–13

Rights & permissionsfor article Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation . Opens in a new window.
Research | 5 May 2014
The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss
- L-H Tsai
- , J-Y Wu
- , Y-W Cheng
- , C-Y Chen
- , G-T Sheu
- , T-C Wu
- & H Lee
Oncogene 34 , 1641–1649

Rights & permissionsfor article The MZF1/c-MYC axis mediates lung adenocarcinoma progression caused by wild-type lkb1 loss . Opens in a new window.
Research | 7 October 2013
Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression
- D-W Wu
- , T-C Wu
- , J-Y Wu
- , Y-W Cheng
- , Y-C Chen
- , M-C Lee
- , C-Y Chen
- & H Lee
Oncogene 33 , 4385–4395

Rights & permissionsfor article Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression . Opens in a new window.
Research | 2 September 2013
LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas
- L-H Tsai
- , P-M Chen
- , Y-W Cheng
- , C-Y Chen
- , G-T Sheu
- , T-C Wu
- & H Lee
Oncogene 33 , 3851–3860

Rights & permissionsfor article LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas . Opens in a new window.
Research | 7 July 2014
FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction
- D-W Wu
- , M-C Lee
- , N-Y Hsu
- , T-C Wu
- , J-Y Wu
- , Y-C Wang
- , Y-W Cheng
- , C-Y Chen
- & H Lee
Oncogene 34 , 2505–2515

Rights & permissionsfor article FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-κB/Slug-mediated PUMA reduction . Opens in a new window.
Research | 28 April 2006
Sindbis virus replicon particles encoding calreticulin linked to a tumor antigen generate long-term tumor-specific immunity
- W-F Cheng
- , C-N Lee
- , Y-N Su
- , C-Y Chai
- , M-C Chang
- , J M Polo
- , C-F Hung
- , T-C Wu
- , C-Y Hsieh
- & C-A Chen
Cancer Gene Therapy 13 , 873–885

Rights & permissionsfor article Sindbis virus replicon particles encoding calreticulin linked to a tumor antigen generate long-term tumor-specific immunity . Opens in a new window.
6 March 2001
Recombinant DNA vaccines protect against tumors that are resistant to recombinant vaccinia vaccines containing the same gene
- C-H Chen
- , T-L Wang
- , H Ji
- , C-F Hung
- , DM Pardoll
- , W-F Cheng
- , M Ling
- & T-C Wu
Gene Therapy 8 , 128–138

Rights & permissionsfor article Recombinant DNA vaccines protect against tumors that are resistant to recombinant vaccinia vaccines containing the same gene . Opens in a new window.
Reviews | 1 October 2006
How will HPV vaccines affect cervical cancer?
- Richard Roden
- & T.-C. Wu
Nature Reviews Cancer 6 , 753–763

Rights & permissionsfor article How will HPV vaccines affect cervical cancer? . Opens in a new window.
1 December 2007 | Open
DNA vaccines for cervical cancer: from bench to bedside
- Chien-Fu Hung
- , Archana Monie
- , Ronald D Alvarez
- & T-C Wu
Experimental & Molecular Medicine 39 , 679–689

Rights & permissionsfor article DNA vaccines for cervical cancer: from bench to bedside . Opens in a new window.
Research | 26 February 2007
Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers
- Y-H Wu
- , J-H Tsai Chang
- , Y-W Cheng
- , T-C Wu
- , C-Y Chen
- & H Lee
Oncogene 26 , 4761–4773

Rights & permissionsfor article Xeroderma pigmentosum group C gene expression is predominantly regulated by promoter hypermethylation and contributes to p53 mutation in lung cancers . Opens in a new window.
8 December 2005
Prospects of RNA interference therapy for cancer
- S I Pai
- , Y-Y Lin
- , B Macaes
- , A Meneshian
- , C-F Hung
- & T-C Wu
Gene Therapy 13 , 464–477

Rights & permissionsfor article Prospects of RNA interference therapy for cancer . Opens in a new window.
Research | 24 May 2010
Subcellular localization of apurinic endonuclease 1 promotes lung tumor aggressiveness via NF-κB activation
- H-H Wu
- , Y-W Cheng
- , J T Chang
- , T-C Wu
- , W-S Liu
- , C-Y Chen
- & H Lee
Oncogene 29 , 4330–4340

Rights & permissionsfor article Subcellular localization of apurinic endonuclease 1 promotes lung tumor aggressiveness via NF-κB activation . Opens in a new window.
Research | 29 July 2010
Efficient delivery of DNA vaccines using human papillomavirus pseudovirions
- S Peng
- , A Monie
- , T H Kang
- , C-F Hung
- , R Roden
- & T-C Wu
Gene Therapy 17 , 1453–1464

Rights & permissionsfor article Efficient delivery of DNA vaccines using human papillomavirus pseudovirions . Opens in a new window.

Quick links