nature.com search

Loading Filters

Showing 1–13 of 13 results

Loading Filters

Research | 20 November 2018 | Open
A rare regulatory variant in the MEF2D gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts
European Journal of Human Genetics 27 , 432–441

Rights & permissionsfor article A rare regulatory variant in the <i>MEF2D</i> gene affects gene regulation and splicing and is associated with a SLE sub-phenotype in Swedish cohorts . Opens in a new window.
Research | 19 December 2012 | Open
Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations
European Journal of Human Genetics 21 , 994–999

Rights & permissionsfor article Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations . Opens in a new window.
Research | 17 September 2018
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes
- Harm-Jan Westra
- , Marta Martínez-Bonet
- , Suna Onengut-Gumuscu
- , Annette Lee
- , Yang Luo
- , Nikola Teslovich
- , Jane Worthington
- , Javier Martin
- , Tom Huizinga
- , Lars Klareskog
- , Solbritt Rantapaa-Dahlqvist
- , Wei-Min Chen
- , Aaron Quinlan
- , John A. Todd
- , Steve Eyre
- , Peter A. Nigrovic
- , Peter K. Gregersen
- , Stephen S. Rich
- & Soumya Raychaudhuri
Nature Genetics 50 , 1366–1374

Rights & permissionsfor article Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes . Opens in a new window.
Research | 30 May 2018 | Open
Common genetic variation in the autoimmune regulator (AIRE) locus is associated with autoimmune Addison’s disease in Sweden
- Daniel Eriksson
- , Matteo Bianchi
- , Nils Landegren
- , Frida Dalin
- , Jakob Skov
- , Lina Hultin-Rosenberg
- , Argyri Mathioudaki
- , Jessika Nordin
- , Åsa Hallgren
- , Göran Andersson
- , Karolina Tandre
- , Solbritt Rantapää Dahlqvist
- , Peter Söderkvist
- , Lars Rönnblom
- , Anna-Lena Hulting
- , Jeanette Wahlberg
- , Per Dahlqvist
- , Olov Ekwall
- , Jennifer R. S. Meadows
- , Kerstin Lindblad-Toh
- , Sophie Bensing
- , Gerli Rosengren Pielberg
- & Olle Kämpe
Scientific Reports 8 , 1–11

Rights & permissionsfor article Common genetic variation in the autoimmune regulator (<i>AIRE</i>) locus is associated with autoimmune Addison’s disease in Sweden . Opens in a new window.
Research | 24 July 2017 | Open
Novel risk genes for systemic lupus erythematosus predicted by random forest classification
Scientific Reports 7 , 1–11

Rights & permissionsfor article Novel risk genes for systemic lupus erythematosus predicted by random forest classification . Opens in a new window.
Research | 17 July 2017 | Open
Transancestral mapping and genetic load in systemic lupus erythematosus
Nature Communications 8 , 1–18

Rights & permissionsfor article Transancestral mapping and genetic load in systemic lupus erythematosus . Opens in a new window.
Research | 16 May 2016
A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases
- Buhm Han
- , Jennie G Pouget
- , Kamil Slowikowski
- , Eli Stahl
- , Cue Hyunkyu Lee
- , Dorothee Diogo
- , Xinli Hu
- , Yu Rang Park
- , Eunji Kim
- , Peter K Gregersen
- , Solbritt Rantapää Dahlqvist
- , Jane Worthington
- , Javier Martin
- , Steve Eyre
- , Lars Klareskog
- , Tom Huizinga
- , Wei-Min Chen
- , Suna Onengut-Gumuscu
- , Stephen S Rich
- , Naomi R Wray
- & Soumya Raychaudhuri
Nature Genetics 48 , 803–810

Rights & permissionsfor article A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases . Opens in a new window.
Research | 13 May 2015
Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes
European Journal of Human Genetics 24 , 263–270

Rights & permissionsfor article Association analysis of copy numbers of FC-gamma receptor genes for rheumatoid arthritis and other immune-mediated phenotypes . Opens in a new window.
Research | 10 August 2015
Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases
- Tobias L Lenz
- , Aaron J Deutsch
- , Buhm Han
- , Xinli Hu
- , Yukinori Okada
- , Stephen Eyre
- , Michael Knapp
- , Alexandra Zhernakova
- , Tom W J Huizinga
- , Gonçalo Abecasis
- , Jessica Becker
- , Guy E Boeckxstaens
- , Wei-Min Chen
- , Andre Franke
- , Dafna D Gladman
- , Ines Gockel
- , Javier Gutierrez-Achury
- , Javier Martin
- , Rajan P Nair
- , Markus M Nöthen
- , Suna Onengut-Gumuscu
- , Proton Rahman
- , Solbritt Rantapää-Dahlqvist
- , Philip E Stuart
- , Lam C Tsoi
- , David A van Heel
- , Jane Worthington
- , Mira M Wouters
- , Lars Klareskog
- , James T Elder
- , Peter K Gregersen
- , Johannes Schumacher
- , Stephen S Rich
- , Cisca Wijmenga
- , Shamil R Sunyaev
- , Paul I W de Bakker
- & Soumya Raychaudhuri
Nature Genetics 47 , 1085–1090

Rights & permissionsfor article Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases . Opens in a new window.
Research | 25 December 2013
Genetics of rheumatoid arthritis contributes to biology and drug discovery
- Yukinori Okada
- , Di Wu
- , Gosia Trynka
- , Towfique Raj
- , Chikashi Terao
- , Katsunori Ikari
- , Yuta Kochi
- , Koichiro Ohmura
- , Akari Suzuki
- , Shinji Yoshida
- , Robert R. Graham
- , Arun Manoharan
- , Ward Ortmann
- , Tushar Bhangale
- , Joshua C. Denny
- , Robert J. Carroll
- , Anne E. Eyler
- , Jeffrey D. Greenberg
- , Joel M. Kremer
- , Dimitrios A. Pappas
- , Lei Jiang
- , Jian Yin
- , Lingying Ye
- , Ding-Feng Su
- , Jian Yang
- , Gang Xie
- , Ed Keystone
- , Harm-Jan Westra
- , Tõnu Esko
- , Andres Metspalu
- , Xuezhong Zhou
- , Namrata Gupta
- , Daniel Mirel
- , Eli A. Stahl
- , Dorothée Diogo
- , Jing Cui
- , Katherine Liao
- , Michael H. Guo
- , Keiko Myouzen
- , Takahisa Kawaguchi
- , Marieke J. H. Coenen
- , Piet L. C. M. van Riel
- , Mart A. F. J. van de Laar
- , Henk-Jan Guchelaar
- , Tom W. J. Huizinga
- , Philippe Dieudé
- , Xavier Mariette
- , S. Louis Bridges Jr
- , Alexandra Zhernakova
- , Rene E. M. Toes
- , Paul P. Tak
- , Corinne Miceli-Richard
- , So-Young Bang
- , Hye-Soon Lee
- , Javier Martin
- , Miguel A. Gonzalez-Gay
- , Luis Rodriguez-Rodriguez
- , Solbritt Rantapää-Dahlqvist
- , Lisbeth Ärlestig
- , Hyon K. Choi
- , Yoichiro Kamatani
- , Pilar Galan
- , Mark Lathrop
- , Steve Eyre
- , John Bowes
- , Anne Barton
- , Niek de Vries
- , Larry W. Moreland
- , Lindsey A. Criswell
- , Elizabeth W. Karlson
- , Atsuo Taniguchi
- , Ryo Yamada
- , Michiaki Kubo
- , Jun S. Liu
- , Sang-Cheol Bae
- , Jane Worthington
- , Leonid Padyukov
- , Lars Klareskog
- , Peter K. Gregersen
- , Soumya Raychaudhuri
- , Barbara E. Stranger
- , Philip L. De Jager
- , Lude Franke
- , Peter M. Visscher
- , Matthew A. Brown
- , Hisashi Yamanaka
- , Tsuneyo Mimori
- , Atsushi Takahashi
- , Huji Xu
- , Timothy W. Behrens
- , Katherine A. Siminovitch
- , Shigeki Momohara
- , Fumihiko Matsuda
- , Kazuhiko Yamamoto
- & Robert M. Plenge
Nature 506 , 376–381

Rights & permissionsfor article Genetics of rheumatoid arthritis contributes to biology and drug discovery . Opens in a new window.
Research | 18 October 2009
A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus
- Vesela Gateva
- , Johanna K Sandling
- , Geoff Hom
- , Kimberly E Taylor
- , Sharon A Chung
- , Xin Sun
- , Ward Ortmann
- , Roman Kosoy
- , Ricardo C Ferreira
- , Gunnel Nordmark
- , Iva Gunnarsson
- , Elisabet Svenungsson
- , Leonid Padyukov
- , Gunnar Sturfelt
- , Andreas Jönsen
- , Anders A Bengtsson
- , Solbritt Rantapää-Dahlqvist
- , Emily C Baechler
- , Elizabeth E Brown
- , Graciela S Alarcón
- , Jeffrey C Edberg
- , Rosalind Ramsey-Goldman
- , Gerald McGwin Jr
- , John D Reveille
- , Luis M Vilá
- , Robert P Kimberly
- , Susan Manzi
- , Michelle A Petri
- , Annette Lee
- , Peter K Gregersen
- , Michael F Seldin
- , Lars Rönnblom
- , Lindsey A Criswell
- , Ann-Christine Syvänen
- , Timothy W Behrens
- & Robert R Graham
Nature Genetics 41 , 1228–1233

Rights & permissionsfor article A large-scale replication study identifies <i>TNIP1, PRDM1, JAZF1, UHRF1BP1</i> and <i>IL10</i> as risk loci for systemic lupus erythematosus . Opens in a new window.
Research | 22 December 2010 | Open
A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE
European Journal of Human Genetics 19 , 479–484

Rights & permissionsfor article A candidate gene study of the type I interferon pathway implicates <i>IKBKE</i> and <i>IL8</i> as risk loci for SLE . Opens in a new window.
Research | 11 November 2012
High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis
- Steve Eyre
- , John Bowes
- , Dorothée Diogo
- , Annette Lee
- , Anne Barton
- , Paul Martin
- , Alexandra Zhernakova
- , Eli Stahl
- , Sebastien Viatte
- , Kate McAllister
- , Christopher I Amos
- , Leonid Padyukov
- , Rene E M Toes
- , Tom W J Huizinga
- , Cisca Wijmenga
- , Gosia Trynka
- , Lude Franke
- , Harm-Jan Westra
- , Lars Alfredsson
- , Xinli Hu
- , Cynthia Sandor
- , Paul I W de Bakker
- , Sonia Davila
- , Chiea Chuen Khor
- , Khai Koon Heng
- , Robert Andrews
- , Sarah Edkins
- , Sarah E Hunt
- , Cordelia Langford
- , Deborah Symmons
- , Pat Concannon
- , Suna Onengut-Gumuscu
- , Stephen S Rich
- , Panos Deloukas
- , Miguel A Gonzalez-Gay
- , Luis Rodriguez-Rodriguez
- , Lisbeth Ärlsetig
- , Javier Martin
- , Solbritt Rantapää-Dahlqvist
- , Robert M Plenge
- , Soumya Raychaudhuri
- , Lars Klareskog
- , Peter K Gregersen
- & Jane Worthington
Nature Genetics 44 , 1336–1340

Rights & permissionsfor article High-density genetic mapping identifies new susceptibility loci for rheumatoid arthritis . Opens in a new window.

Quick links