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Amendments and Corrections | 1 September 2002
Erratum: Digenic inheritance of severe insulin resistance in a human pedigree
- D B Savage
- , M Agostini
- , I Barroso
- , M Gurnell
- , J Luan
- , A Meirhaeghe
- , A-H Harding
- , G Ihrke
- , O Rajanayagam
- , M A Soos
- , S George
- , D Berger
- , E L Thomas
- , J D Bell
- , K Meeran
- , R J Ross
- , A Vidal-Puig
- , N J Wareham
- , S O'Rahilly
- , V K K Chatterjee
- & A J Schafer
Nature Genetics 32 , 211–211

Rights & permissionsfor article Erratum: Digenic inheritance of severe insulin resistance in a human pedigree . Opens in a new window.
30 April 2015
Response to ‘Energy balance measurement: when something is not better than nothing’
- N V Dhurandhar
- , D A Schoeller
- , A W Brown
- , S B Heymsfield
- , D Thomas
- , T I A Sørensen
- , J R Speakman
- , M Jeansonne
- , D B Allison
- , A Astrup
- , R L Atkinson
- , M Binks
- , G Blackburn
- , J E Blundell
- , M M B Brown
- , N M Byrne
- , L J Cheskin
- , R Cooper
- , B E Corkey
- , J P Foreyt
- , P Franks
- , Y Freedhoff
- , M Goran
- , B C Hansen
- , J Hebebrand
- , B L Heitmann
- , J O Hill
- , A P Hills
- , G R Hunter
- , T Kyle
- , D A Levitsky
- , A Luke
- , I Macdonald
- , R Matthews
- , C K Martin
- , A Y McDermott
- , T Moran
- , S O'Rahilly
- , A Pietrobelli
- , S Rössner
- , W H M Saris
- , A Sharma
- , J Stern
- , L V Gaal
- , S S Young
- & S Zhu
International Journal of Obesity 39 , 1175–1176

Rights & permissionsfor article Response to ‘Energy balance measurement: when something is not better than nothing’ . Opens in a new window.
Amendments and Corrections | 30 September 2014
Erratum: Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects
- H Ziauddeen
- , S R Chamberlain
- , P J Nathan
- , A Koch
- , K Maltby
- , M Bush
- , W X Tao
- , A Napolitano
- , A L Skeggs
- , A C Brooke
- , L Cheke
- , N S Clayton
- , I Sadaf Farooqi
- , S O'Rahilly
- , D Waterworth
- , K Song
- , L Hosking
- , D B Richards
- , P C Fletcher
- & E T Bullmore
Molecular Psychiatry 19 , 1341–1341

Rights & permissionsfor article Erratum: Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects . Opens in a new window.
Editorial | 12 September 2005
New advances in the genetics of early onset obesity
- I S Farooqi
- & S O'Rahilly
International Journal of Obesity 29 , 1149–1152

Rights & permissionsfor article New advances in the genetics of early onset obesity . Opens in a new window.
Correspondence | 6 July 2018
GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity
International Journal of Obesity 42 , 1524–1531

Rights & permissionsfor article GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity . Opens in a new window.
Research | 11 December 2007
The NR4A family of orphan nuclear receptors are not required for adipogenesis
- W-S Au
- , V A Payne
- , S O'Rahilly
- & J J Rochford
International Journal of Obesity 32 , 388–392

Rights & permissionsfor article The NR4A family of orphan nuclear receptors are not required for adipogenesis . Opens in a new window.
Research | 22 August 2006
Studies of the SIM1 gene in relation to human obesity and obesity-related traits
- C-C C Hung
- , J Luan
- , M Sims
- , J M Keogh
- , C Hall
- , N J Wareham
- , S O'Rahilly
- & I S Farooqi
International Journal of Obesity 31 , 429–434

Rights & permissionsfor article Studies of the SIM1 gene in relation to human obesity and obesity-related traits . Opens in a new window.
Research | 29 November 2011 | Open
Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis
- C E Lowe
- , R J Dennis
- , U Obi
- , S O'Rahilly
- & J J Rochford
International Journal of Obesity 36 , 1248–1251

Rights & permissionsfor article Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis . Opens in a new window.
31 May 2000
Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes
- JE Digby
- , VEF Crowley
- , CP Sewter
- , JP Whitehead
- , JB Prins
- & S O'Rahilly
International Journal of Obesity 24 , 585–592

Rights & permissionsfor article Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes . Opens in a new window.
Research | 23 December 1999
Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension
- I. Barroso
- , M. Gurnell
- , V. E. F. Crowley
- , M. Agostini
- , J. W. Schwabe
- , M. A. Soos
- , G. LI Maslen
- , T. D. M. Williams
- , H. Lewis
- , A. J. Schafer
- , V. K. K. Chatterjee
- & S. O'Rahilly
Nature 402 , 880–883

Rights & permissionsfor article Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension . Opens in a new window.
Research | 16 May 2006
Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity
- J Gray
- , G Yeo
- , C Hung
- , J Keogh
- , P Clayton
- , K Banerjee
- , A McAulay
- , S O'Rahilly
- & I S Farooqi
International Journal of Obesity 31 , 359–364

Rights & permissionsfor article Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity . Opens in a new window.
Research | 20 October 2009
Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent
- S Romeo
- , F Sentinelli
- , S Dash
- , G S H Yeo
- , D B Savage
- , F Leonetti
- , D Capoccia
- , M Incani
- , C Maglio
- , M Iacovino
- , S O'Rahilly
- & M G Baroni
International Journal of Obesity 34 , 190–194

Rights & permissionsfor article Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent . Opens in a new window.
Research | 13 March 2007
The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals
- E H Young
- , N J Wareham
- , S Farooqi
- , A Hinney
- , J Hebebrand
- , A Scherag
- , S O'Rahilly
- , I Barroso
- & M S Sandhu
International Journal of Obesity 31 , 1437–1441

Rights & permissionsfor article The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals . Opens in a new window.
6 July 2001
Adipose depot-specific expression of cIAP2 in human preadipocytes and modulation of expression by serum factors and TNFα
- CU Niesler
- , JB Prins
- , S O'Rahilly
- , K Siddle
- & CT Montague
International Journal of Obesity 25 , 1027–1033

Rights & permissionsfor article Adipose depot-specific expression of cIAP2 in human preadipocytes and modulation of expression by serum factors and TNFα . Opens in a new window.
13 January 2004
Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians
- B G Challis
- , J Luan
- , J Keogh
- , N J Wareham
- , I S Farooqi
- & S O'Rahilly
International Journal of Obesity 28 , 442–446

Rights & permissionsfor article Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians . Opens in a new window.
20 April 2001
Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population
- DJ Halsall
- , J Luan
- , P Saker
- , S Huxtable
- , IS Farooqi
- , J Keogh
- , NJ Wareham
- & S O'Rahilly
International Journal of Obesity 25 , 472–477

Rights & permissionsfor article Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population . Opens in a new window.
Research | 22 May 2012
FTO expression is regulated by availability of essential amino acids
- M K Cheung
- , P Gulati
- , S O'Rahilly
- & G S H Yeo
International Journal of Obesity 37 , 744–747

Rights & permissionsfor article FTO expression is regulated by availability of essential amino acids . Opens in a new window.
Research | 7 October 2003
Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects
- R K Semple
- , V C Crowley
- , C P Sewter
- , M Laudes
- , C Christodoulides
- , R V Considine
- , A Vidal-Puig
- & S O'Rahilly
International Journal of Obesity 28 , 176–179

Rights & permissionsfor article Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects . Opens in a new window.
12 January 2009
Human obesity as a heritable disorder of the central control of energy balance
- S O'Rahilly
- & I S Farooqi
International Journal of Obesity 32 , S55–S61

Rights & permissionsfor article Human obesity as a heritable disorder of the central control of energy balance . Opens in a new window.
Research | 13 November 2012 | Open
Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects
- H Ziauddeen
- , S R Chamberlain
- , P J Nathan
- , A Koch
- , K Maltby
- , M Bush
- , W X Tao
- , A Napolitano
- , A L Skeggs
- , A C Brooke
- , L Cheke
- , N S Clayton
- , I Sadaf Farooqi
- , S O'Rahilly
- , D Waterworth
- , K Song
- , L Hosking
- , D B Richards
- , P C Fletcher
- & E T Bullmore
Molecular Psychiatry 18 , 1287–1293

Rights & permissionsfor article Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects . Opens in a new window.
Research | 4 February 2010
A new highly penetrant form of obesity due to deletions on chromosome 16p11.2
- R. G. Walters
- , S. Jacquemont
- , A. Valsesia
- , A. J. de Smith
- , D. Martinet
- , J. Andersson
- , M. Falchi
- , F. Chen
- , J. Andrieux
- , S. Lobbens
- , B. Delobel
- , F. Stutzmann
- , J. S. El-Sayed Moustafa
- , J.-C. Chèvre
- , C. Lecoeur
- , V. Vatin
- , S. Bouquillon
- , J. L. Buxton
- , O. Boute
- , M. Holder-Espinasse
- , J.-M. Cuisset
- , M.-P. Lemaitre
- , A.-E. Ambresin
- , A. Brioschi
- , M. Gaillard
- , V. Giusti
- , F. Fellmann
- , A. Ferrarini
- , N. Hadjikhani
- , D. Campion
- , A. Guilmatre
- , A. Goldenberg
- , N. Calmels
- , J.-L. Mandel
- , C. Le Caignec
- , A. David
- , B. Isidor
- , M.-P. Cordier
- , S. Dupuis-Girod
- , A. Labalme
- , D. Sanlaville
- , M. Béri-Dexheimer
- , P. Jonveaux
- , B. Leheup
- , K. Õunap
- , E. G. Bochukova
- , E. Henning
- , J. Keogh
- , R. J. Ellis
- , K. D. MacDermot
- , M. M. van Haelst
- , C. Vincent-Delorme
- , G. Plessis
- , R. Touraine
- , A. Philippe
- , V. Malan
- , M. Mathieu-Dramard
- , J. Chiesa
- , B. Blaumeiser
- , R. F. Kooy
- , R. Caiazzo
- , M. Pigeyre
- , B. Balkau
- , R. Sladek
- , S. Bergmann
- , V. Mooser
- , D. Waterworth
- , A. Reymond
- , P. Vollenweider
- , G. Waeber
- , A. Kurg
- , P. Palta
- , T. Esko
- , A. Metspalu
- , M. Nelis
- , P. Elliott
- , A.-L. Hartikainen
- , M. I. McCarthy
- , L. Peltonen
- , L. Carlsson
- , P. Jacobson
- , L. Sjöström
- , N. Huang
- , M. E. Hurles
- , S. O’Rahilly
- , I. S. Farooqi
- , K. Männik
- , M.-R. Jarvelin
- , F. Pattou
- , D. Meyre
- , A. J. Walley
- , L. J. M. Coin
- , A. I. F. Blakemore
- , P. Froguel
- & J. S. Beckmann
Nature 463 , 671–675

Rights & permissionsfor article A new highly penetrant form of obesity due to deletions on chromosome 16p11.2 . Opens in a new window.
20 February 2009
The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation
- K B Boyle
- , D Hadaschik
- , S Virtue
- , W P Cawthorn
- , S H Ridley
- , S O'Rahilly
- & K Siddle
Cell Death and Differentiation 16 , 782–789

Rights & permissionsfor article The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation . Opens in a new window.

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Erratum: Digenic inheritance of severe insulin resistance in a human pedigree

Response to ‘Energy balance measurement: when something is not better than nothing’

Erratum: Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects

New advances in the genetics of early onset obesity

GWAS for BMI: a treasure trove of fundamental insights into the genetic basis of obesity

The NR4A family of orphan nuclear receptors are not required for adipogenesis

Studies of the SIM1 gene in relation to human obesity and obesity-related traits

Investigating the involvement of the ATF6α pathway of the unfolded protein response in adipogenesis

Depot-related and thiazolidinedione-responsive expression of uncoupling protein 2 (UCP2) in human adipocytes

Dominant negative mutations in human PPARγ associated with severe insulin resistance, diabetes mellitus and hypertension

Functional characterization of human NTRK2 mutations identified in patients with severe early-onset obesity

Morbid obesity exposes the association between PNPLA3 I148M (rs738409) and indices of hepatic injury in individuals of European descent

The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals

Adipose depot-specific expression of cIAP2 in human preadipocytes and modulation of expression by serum factors and TNFα

Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians

Uncoupling protein 3 genetic variants in human obesity: the c-55t promoter polymorphism is negatively correlated with body mass index in a UK Caucasian population

FTO expression is regulated by availability of essential amino acids

Expression of the thermogenic nuclear hormone receptor coactivator PGC-1α is reduced in the adipose tissue of morbidly obese subjects

Human obesity as a heritable disorder of the central control of energy balance

Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects

A new highly penetrant form of obesity due to deletions on chromosome 16p11.2

The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation

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