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Showing 1–16 of 16 results

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News and Views | 1 September 2017
Genetic insights into mammalian heart regeneration
Nature Genetics 49 , 1292–1293

Rights & permissionsfor article Genetic insights into mammalian heart regeneration . Opens in a new window.
News and Views | 12 December 2016
Suffocating the heart to stimulate regeneration
- Niranjana Natarajan
- & Richard T. Lee
Nature Reviews Cardiology 14 , 7–8

Rights & permissionsfor article Suffocating the heart to stimulate regeneration . Opens in a new window.
4 April 2013
Is heart regeneration on the right track?
- ..., Christine L. Mummery and Richard T. Lee lay out a framework for...
- Christine L Mummery
- & Richard T Lee
Nature Medicine 19 , 412–413

Rights & permissionsfor article Is heart regeneration on the right track? . Opens in a new window.
Research | 12 March 2020 | Open
Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice
- Ryan G. Walker
- , Ornella Barrandon
- , Tommaso Poggioli
- , Sezin Dagdeviren
- , Shannon H. Carroll
- , Melanie J. Mills
- , Kourtney R. Mendello
- , Yanet Gomez
- , Francesco S. Loffredo
- , James R. Pancoast
- , Claudio Macias-Trevino
- , Colin Marts
- , Katherine B. LeClair
- , Hye-Lim Noh
- , Taekyoon Kim
- , Alexander S. Banks
- , Jason K. Kim
- , David E. Cohen
- , Amy J. Wagers
- , Douglas A. Melton
- & Richard T. Lee
Scientific Reports 10 , 1–13

Rights & permissionsfor article Exogenous GDF11, but not GDF8, reduces body weight and improves glucose homeostasis in mice . Opens in a new window.
Research | 9 December 2019 | Open
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus
- Jill M. Goldstein
- , Austin Valido
- , Jordan P. Lewandowski
- , Ryan G. Walker
- , Melanie J. Mills
- , Kathleen A. Messemer
- , Paul Besseling
- , Kyu Ha Lee
- , Samuel J. Wattrus
- , Miook Cho
- , Richard T. Lee
- & Amy J. Wagers
Scientific Reports 9 , 1–19

Rights & permissionsfor article Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the <i>Gdf11</i> locus . Opens in a new window.
Reviews | 20 February 2008
Stem-cell therapy for cardiac disease
- Vincent F. M. Segers
- & Richard T. Lee
Nature 451 , 937–942

Rights & permissionsfor article Stem-cell therapy for cardiac disease . Opens in a new window.
Research | 5 December 2012
Mammalian heart renewal by pre-existing cardiomyocytes
- Samuel E. Senyo
- , Matthew L. Steinhauser
- , Christie L. Pizzimenti
- , Vicky K. Yang
- , Lei Cai
- , Mei Wang
- , Ting-Di Wu
- , Jean-Luc Guerquin-Kern
- , Claude P. Lechene
- & Richard T. Lee
Nature 493 , 433–436

Rights & permissionsfor article Mammalian heart renewal by pre-existing cardiomyocytes . Opens in a new window.
Research | 15 January 2012
Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism
Nature 481 , 516–519

Rights & permissionsfor article Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism . Opens in a new window.
Research | 29 July 2007
Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury
Nature Medicine 13 , 970–974

Rights & permissionsfor article Evidence from a genetic fate-mapping study that stem cells refresh adult mammalian cardiomyocytes after injury . Opens in a new window.
19 January 2009
Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II
- Jun-o Deguchi
- , Hayden Huang
- , Peter Libby
- , Elena Aikawa
- , Peter Whittaker
- , Jeremy Sylvan
- , Richard T Lee
- & Masanori Aikawa
Laboratory Investigation 89 , 315–326

Rights & permissionsfor article Genetically engineered resistance for MMP collagenases promotes abdominal aortic aneurysm formation in mice infused with angiotensin II . Opens in a new window.
Research | 23 April 2019 | Open
Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression
- Peiying Yang
- , Yan Jiang
- , Yong Pan
- , Xiaoping Ding
- , Patrea Rhea
- , Jibin Ding
- , David H. Hawke
- , Dean Felsher
- , Goutham Narla
- , Zhimin Lu
- & Richard T. Lee
Scientific Reports 9 , 1–12

Rights & permissionsfor article Mistletoe extract Fraxini inhibits the proliferation of liver cancer by down-regulating c-Myc expression . Opens in a new window.
Research | 25 April 2018 | Open
Exercise induces new cardiomyocyte generation in the adult mammalian heart
Nature Communications 9 , 1–9

Rights & permissionsfor article Exercise induces new cardiomyocyte generation in the adult mammalian heart . Opens in a new window.
Reviews | 6 September 2017
Multiscale technologies for treatment of ischemic cardiomyopathy
- Morteza Mahmoudi
- , Mikyung Yu
- , Vahid Serpooshan
- , Joseph C. Wu
- , Robert Langer
- , Richard T. Lee
- , Jeffrey M. Karp
- & Omid C. Farokhzad
Nature Nanotechnology 12 , 845–855

Rights & permissionsfor article Multiscale technologies for treatment of ischemic cardiomyopathy . Opens in a new window.
Research | 4 October 2013 | Open
Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells
- Wei Li
- , Samuel Lee
- , Minglin Ma
- , Soo Min Kim
- , Patrick Guye
- , James R. Pancoast
- , Daniel G. Anderson
- , Ron Weiss
- , Richard T. Lee
- & Paula T. Hammond
Scientific Reports 3 , 1–10

Rights & permissionsfor article Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells . Opens in a new window.
Research | 28 April 2015 | Open
A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity
- Shuxi Qiao
- , Michael Dennis
- , Xiufeng Song
- , Douangsone D. Vadysirisack
- , Devika Salunke
- , Zachary Nash
- , Zhifen Yang
- , Marc Liesa
- , Jun Yoshioka
- , Shu-Ichi Matsuzawa
- , Orian S. Shirihai
- , Richard T. Lee
- , John C. Reed
- & Leif W. Ellisen
Nature Communications 6 , 1–13

Rights & permissionsfor article A REDD1/TXNIP pro-oxidant complex regulates ATG4B activity to control stress-induced autophagy and sustain exercise capacity . Opens in a new window.
Reviews | 1 October 2008
The IL-33/ST2 pathway: therapeutic target and novel biomarker
- Rahul Kakkar
- & Richard T. Lee
Nature Reviews Drug Discovery 7 , 827–840

Rights & permissionsfor article The IL-33/ST2 pathway: therapeutic target and novel biomarker . Opens in a new window.

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