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Research | 5 January 2021 | Open
Parkinson’s disease with restless legs syndrome—an in vivo corneal confocal microscopy study
- Mattias Andréasson
- , Neil Lagali
- , Reza A. Badian
- , Tor Paaske Utheim
- , Fabio Scarpa
- , Alessia Colonna
- , Stephan Allgeier
- , Andreas Bartschat
- , Bernd Köhler
- , Ralf Mikut
- , Klaus-Martin Reichert
- , Göran Solders
- , Kristin Samuelsson
- , Henrik Zetterberg
- , Kaj Blennow
- & Per Svenningsson
npj Parkinson's Disease 7 , 1–8

Rights & permissionsfor article Parkinson’s disease with restless legs syndrome—an in vivo corneal confocal microscopy study . Opens in a new window.
Research | 1 June 2020 | Open
A randomized placebo-controlled PET study of ketamine´s effect on serotonin_1B receptor binding in patients with SSRI-resistant depression
Translational Psychiatry 10 , 1–8

Rights & permissionsfor article A randomized placebo-controlled PET study of ketamine´s effect on serotonin<sub>1B</sub> receptor binding in patients with SSRI-resistant depression . Opens in a new window.
Research | 1 October 2020 | Open
P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness
- Vasco C. Sousa
- , Ioannis Mantas
- , Nikolas Stroth
- , Torben Hager
- , Marcela Pereira
- , Haitang Jiang
- , Sandra Jabre
- , Wojciech Paslawski
- , Oliver Stiedl
- & Per Svenningsson
Molecular Psychiatry , 1–13

Rights & permissionsfor article P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness . Opens in a new window.
Research | 25 October 2019 | Open
Polyneuropathy in Gaucher disease type 1 and 3 – a descriptive case series
Scientific Reports 9 , 1–6

Rights & permissionsfor article Polyneuropathy in Gaucher disease type 1 and 3 – a descriptive case series . Opens in a new window.
Research | 24 June 2019 | Open
Vertical saccades and antisaccades: complementary markers for motor and cognitive impairment in Parkinson’s disease
npj Parkinson's Disease 5 , 1–6

Rights & permissionsfor article Vertical saccades and antisaccades: complementary markers for motor and cognitive impairment in Parkinson’s disease . Opens in a new window.
Research | 15 April 2019 | Open
Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism
- Henrik Sjöström
- , Yulia Surova
- , Markus Nilsson
- , Tobias Granberg
- , Eric Westman
- , Danielle van Westen
- , Per Svenningsson
- & Oskar Hansson
Scientific Reports 9 , 1–9

Rights & permissionsfor article Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism . Opens in a new window.
Research | 6 December 2018 | Open
Safety and tolerability of IRL790 in Parkinson’s disease with levodopa-induced dyskinesia—a phase 1b trial
- Per Svenningsson
- , Anders Johansson
- , Dag Nyholm
- , Panagiota Tsitsi
- , Fredrik Hansson
- , Clas Sonesson
- & Joakim Tedroff
npj Parkinson's Disease 4 , 1–5

Rights & permissionsfor article Safety and tolerability of IRL790 in Parkinson’s disease with levodopa-induced dyskinesia—a phase 1b trial . Opens in a new window.
Reviews | 22 April 2020
An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders
- Nicholas J. Ashton
- , Abdul Hye
- , Anto P. Rajkumar
- , Antoine Leuzy
- , Stuart Snowden
- , Marc Suárez-Calvet
- , Thomas K. Karikari
- , Michael Schöll
- , Renaud La Joie
- , Gil D. Rabinovici
- , Kina Höglund
- , Clive Ballard
- , Tibor Hortobágyi
- , Per Svenningsson
- , Kaj Blennow
- , Henrik Zetterberg
- & Dag Aarsland
Nature Reviews Neurology 16 , 265–284

Rights & permissionsfor article An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders . Opens in a new window.
Research | 8 February 2017 | Open
Synaptic proteins in CSF relate to Parkinson’s disease stage markers
- Erika Bereczki
- , Anna Bogstedt
- , Kina Höglund
- , Panagiota Tsitsi
- , Lovisa Brodin
- , Clive Ballard
- , Per Svenningsson
- & Dag Aarsland
npj Parkinson's Disease 3 , 1–5

Rights & permissionsfor article Synaptic proteins in CSF relate to Parkinson’s disease stage markers . Opens in a new window.
Reviews | 4 September 2013
p11 and its role in depression and therapeutic responses to antidepressants
Nature Reviews Neuroscience 14 , 673–680

Rights & permissionsfor article p11 and its role in depression and therapeutic responses to antidepressants . Opens in a new window.
Research | 15 August 2002
Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine
- Maria Lindskog
- , Per Svenningsson
- , Laura Pozzi
- , Yong Kim
- , Allen A. Fienberg
- , James A. Bibb
- , Bertil B. Fredholm
- , Angus C. Nairn
- , Paul Greengard
- & Gilberto Fisone
Nature 418 , 774–778

Rights & permissionsfor article Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine . Opens in a new window.
Research | 3 August 2005
Phosphorylation of DARPP-32 at Threonine-34 is Required for Cocaine Action
Neuropsychopharmacology 31 , 555–562

Rights & permissionsfor article Phosphorylation of DARPP-32 at Threonine-34 is Required for Cocaine Action . Opens in a new window.
Research | 15 March 2001
Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5
- James A. Bibb
- , Jingshan Chen
- , Jane R. Taylor
- , Per Svenningsson
- , Akinori Nishi
- , Gretchen L. Snyder
- , Zhen Yan
- , Zachary K. Sagawa
- , Charles C. Ouimet
- , Angus C. Nairn
- , Eric J. Nestler
- & Paul Greengard
Nature 410 , 376–380

Rights & permissionsfor article Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5 . Opens in a new window.
Research | 23 September 2019
Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging
- Mohammadreza Shariatgorji
- , Anna Nilsson
- , Elva Fridjonsdottir
- , Theodosia Vallianatou
- , Patrik Källback
- , Luay Katan
- , Jonas Sävmarker
- , Ioannis Mantas
- , Xiaoqun Zhang
- , Erwan Bezard
- , Per Svenningsson
- , Luke R. Odell
- & Per E. Andrén
Nature Methods 16 , 1021–1028

Rights & permissionsfor article Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging . Opens in a new window.
Research | 22 April 2019 | Open
Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition
Neuropsychopharmacology 44 , 2091–2098

Rights & permissionsfor article Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition . Opens in a new window.
Research | 22 February 2019 | Open
Attenuated beta rebound to proprioceptive afferent feedback in Parkinson’s disease
Scientific Reports 9 , 1–11

Rights & permissionsfor article Attenuated beta rebound to proprioceptive afferent feedback in Parkinson’s disease . Opens in a new window.
Research | 23 May 2016 | Open
α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter
- Oi Wan Wan
- , Eunju Shin
- , Bengt Mattsson
- , Dorian Caudal
- , Per Svenningsson
- & Anders Björklund
Scientific Reports 6 , 1–12

Rights & permissionsfor article α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter . Opens in a new window.
Research | 27 April 2015
Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease
- Ariadna Laguna
- , Nicoletta Schintu
- , André Nobre
- , Alexandra Alvarsson
- , Nikolaos Volakakis
- , Jesper Kjaer Jacobsen
- , Marta Gómez-Galán
- , Elena Sopova
- , Eliza Joodmardi
- , Takashi Yoshitake
- , Qiaolin Deng
- , Jan Kehr
- , Johan Ericson
- , Per Svenningsson
- , Oleg Shupliakov
- & Thomas Perlmann
Nature Neuroscience 18 , 826–835

Rights & permissionsfor article Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease . Opens in a new window.
21 August 2013
Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology
Neuropsychopharmacology 39 , 34–49

Rights & permissionsfor article Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology . Opens in a new window.
Research | 4 May 2015
Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export
- Andrea Legati
- , Donatella Giovannini
- , Gaël Nicolas
- , Uriel López-Sánchez
- , Beatriz Quintáns
- , João R M Oliveira
- , Renee L Sears
- , Eliana Marisa Ramos
- , Elizabeth Spiteri
- , María-Jesús Sobrido
- , Ángel Carracedo
- , Cristina Castro-Fernández
- , Stéphanie Cubizolle
- , Brent L Fogel
- , Cyril Goizet
- , Joanna C Jen
- , Suppachok Kirdlarp
- , Anthony E Lang
- , Zosia Miedzybrodzka
- , Witoon Mitarnun
- , Martin Paucar
- , Henry Paulson
- , Jérémie Pariente
- , Anne-Claire Richard
- , Naomi S Salins
- , Sheila A Simpson
- , Pasquale Striano
- , Per Svenningsson
- , François Tison
- , Vivek K Unni
- , Olivier Vanakker
- , Marja W Wessels
- , Suppachok Wetchaphanphesat
- , Michele Yang
- , Francois Boller
- , Dominique Campion
- , Didier Hannequin
- , Marc Sitbon
- , Daniel H Geschwind
- , Jean-Luc Battini
- & Giovanni Coppola
Nature Genetics 47 , 579–581

Rights & permissionsfor article Mutations in <i>XPR1</i> cause primary familial brain calcification associated with altered phosphate export . Opens in a new window.
Reviews | 16 December 2014
Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases
- Alberto Lleó
- , Enrica Cavedo
- , Lucilla Parnetti
- , Hugo Vanderstichele
- , Sanna Kaisa Herukka
- , Niels Andreasen
- , Roberta Ghidoni
- , Piotr Lewczuk
- , Andreas Jeromin
- , Bengt Winblad
- , Magda Tsolaki
- , Barbara Mroczko
- , Pieter Jelle Visser
- , Isabel Santana
- , Per Svenningsson
- , Kaj Blennow
- , Dag Aarsland
- , José Luis Molinuevo
- , Henrik Zetterberg
- & Brit Mollenhauer
Nature Reviews Neurology 11 , 41–55

Rights & permissionsfor article Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases . Opens in a new window.
Research | 4 August 2013
Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice
- Annika Keller
- , Ana Westenberger
- , Maria J Sobrido
- , Maria García-Murias
- , Aloysius Domingo
- , Renee L Sears
- , Roberta R Lemos
- , Andres Ordoñez-Ugalde
- , Gael Nicolas
- , José E Gomes da Cunha
- , Elisabeth J Rushing
- , Michael Hugelshofer
- , Moritz C Wurnig
- , Andres Kaech
- , Regina Reimann
- , Katja Lohmann
- , Valerija Dobričić
- , Angel Carracedo
- , Igor Petrović
- , Janis M Miyasaki
- , Irina Abakumova
- , Maarja Andaloussi Mäe
- , Elisabeth Raschperger
- , Mayana Zatz
- , Katja Zschiedrich
- , Jörg Klepper
- , Elizabeth Spiteri
- , Jose M Prieto
- , Inmaculada Navas
- , Michael Preuss
- , Carmen Dering
- , Milena Janković
- , Martin Paucar
- , Per Svenningsson
- , Kioomars Saliminejad
- , Hamid R K Khorshid
- , Ivana Novaković
- , Adriano Aguzzi
- , Andreas Boss
- , Isabelle Le Ber
- , Gilles Defer
- , Didier Hannequin
- , Vladimir S Kostić
- , Dominique Campion
- , Daniel H Geschwind
- , Giovanni Coppola
- , Christer Betsholtz
- , Christine Klein
- & Joao R M Oliveira
Nature Genetics 45 , 1077–1082

Rights & permissionsfor article Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice . Opens in a new window.
Protocols | 11 June 2009
Coupling surface plasmon resonance to mass spectrometry to discover novel protein–protein interactions
Nature Protocols 4 , 1023–1037

Rights & permissionsfor article Coupling surface plasmon resonance to mass spectrometry to discover novel protein–protein interactions . Opens in a new window.
Reviews | 26 December 2011
Depression in Parkinson disease—epidemiology, mechanisms and management
- Dag Aarsland
- , Sven Påhlhagen
- , Clive G. Ballard
- , Uwe Ehrt
- & Per Svenningsson
Nature Reviews Neurology 8 , 35–47

Rights & permissionsfor article Depression in Parkinson disease—epidemiology, mechanisms and management . Opens in a new window.
1 March 2007
How can drug discovery for psychiatric disorders be improved?
- Yves Agid
- , György Buzsáki
- , David M. Diamond
- , Richard Frackowiak
- , Jay Giedd
- , Jean-Antoine Girault
- , Anthony Grace
- , Jeremy J. Lambert
- , Husseini Manji
- , Helen Mayberg
- , Maurizio Popoli
- , Alain Prochiantz
- , Gal Richter-Levin
- , Peter Somogyi
- , Michael Spedding
- , Per Svenningsson
- & Daniel Weinberger
Nature Reviews Drug Discovery 6 , 189–201

Rights & permissionsfor article How can drug discovery for psychiatric disorders be improved? . Opens in a new window.
Research | 11 July 2008
Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs
- Helen S Bateup
- , Per Svenningsson
- , Mahomi Kuroiwa
- , Shiaoching Gong
- , Akinori Nishi
- , Nathaniel Heintz
- & Paul Greengard
Nature Neuroscience 11 , 932–939

Rights & permissionsfor article Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs . Opens in a new window.

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Parkinson’s disease with restless legs syndrome—an in vivo corneal confocal microscopy study

A randomized placebo-controlled PET study of ketamine´s effect on serotonin_1B receptor binding in patients with SSRI-resistant depression

P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

Polyneuropathy in Gaucher disease type 1 and 3 – a descriptive case series

Vertical saccades and antisaccades: complementary markers for motor and cognitive impairment in Parkinson’s disease

Mapping of apparent susceptibility yields promising diagnostic separation of progressive supranuclear palsy from other causes of parkinsonism

Safety and tolerability of IRL790 in Parkinson’s disease with levodopa-induced dyskinesia—a phase 1b trial

An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders

Synaptic proteins in CSF relate to Parkinson’s disease stage markers

p11 and its role in depression and therapeutic responses to antidepressants

Involvement of DARPP-32 phosphorylation in the stimulant action of caffeine

Phosphorylation of DARPP-32 at Threonine-34 is Required for Cocaine Action

Effects of chronic exposure to cocaine are regulated by the neuronal protein Cdk5

Comprehensive mapping of neurotransmitter networks by MALDI–MS imaging

Molecular imaging identifies age-related attenuation of acetylcholine in retrosplenial cortex in response to acetylcholinesterase inhibition

Attenuated beta rebound to proprioceptive afferent feedback in Parkinson’s disease

α-Synuclein induced toxicity in brain stem serotonin neurons mediated by an AAV vector driven by the tryptophan hydroxylase promoter

Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease

Mass Spectrometry Imaging, an Emerging Technology in Neuropsychopharmacology

Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export

Cerebrospinal fluid biomarkers in trials for Alzheimer and Parkinson diseases

Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice

Coupling surface plasmon resonance to mass spectrometry to discover novel protein–protein interactions

Depression in Parkinson disease—epidemiology, mechanisms and management

How can drug discovery for psychiatric disorders be improved?

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

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