Showing 1–18 of 18 results
-
Amendments and Corrections | | Open
-
Research |
Plasticity of ether lipids promotes ferroptosis susceptibility and evasion
- Yilong Zou
- , Whitney S. Henry
- , Emily L. Ricq
- , Emily T. Graham
- , Vaishnavi V. Phadnis
- , Pema Maretich
- , Sateja Paradkar
- , Natalie Boehnke
- , Amy A. Deik
- , Ferenc Reinhardt
- , John K. Eaton
- , Bryan Ferguson
- , Wenyu Wang
- , Joshua Fairman
- , Heather R. Keys
- , Vlado Dančík
- , Clary B. Clish
- , Paul A. Clemons
- , Paula T. Hammond
- , Laurie A. Boyer
- , Robert A. Weinberg
- & Stuart L. Schreiber
-
Research |
Small-molecule targeting of brachyury transcription factor addiction in chordoma
- Tanaz Sharifnia
- , Mathias J. Wawer
- , Ting Chen
- , Qing-Yuan Huang
- , Barbara A. Weir
- , Ann Sizemore
- , Matthew A. Lawlor
- , Amy Goodale
- , Glenn S. Cowley
- , Francisca Vazquez
- , Christopher J. Ott
- , Joshua M. Francis
- , Slim Sassi
- , Patricia Cogswell
- , Hadley E. Sheppard
- , Tinghu Zhang
- , Nathanael S. Gray
- , Paul A. Clarke
- , Julian Blagg
- , Paul Workman
- , Josh Sommer
- , Francis Hornicek
- , David E. Root
- , William C. Hahn
- , James E. Bradner
- , Kwok K. Wong
- , Paul A. Clemons
- , Charles Y. Lin
- , Joanne D. Kotz
- & Stuart L. Schreiber
-
Research |
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles
- John K. Eaton
- , Laura Furst
- , Richard A. Ruberto
- , Dieter Moosmayer
- , André Hilpmann
- , Matthew J. Ryan
- , Katja Zimmermann
- , Luke L. Cai
- , Michael Niehues
- , Volker Badock
- , Anneke Kramm
- , Sixun Chen
- , Roman C. Hillig
- , Paul A. Clemons
- , Stefan Gradl
- , Claire Montagnon
- , Kiel E. Lazarski
- , Sven Christian
- , Besnik Bajrami
- , Roland Neuhaus
- , Ashley L. Eheim
- , Vasanthi S. Viswanathan
- & Stuart L. Schreiber
-
Towards patient-based cancer therapeutics
- Stuart L Schreiber
- , Alykhan F Shamji
- , Paul A Clemons
- , Cindy Hon
- , Angela N Koehler
- , Benito Munoz
- , Michelle Palmer
- , Andrew M Stern
- , Bridget K Wagner
- , Scott Powers
- , Scott W Lowe
- , Xuecui Guo
- , Alex Krasnitz
- , Eric T Sawey
- , Raffaella Sordella
- , Lincoln Stein
- , Lloyd C Trotman
- , Andrea Califano
- , Riccardo Dalla-Favera
- , Adolfo Ferrando
- , Antonio Iavarone
- , Laura Pasqualucci
- , José Silva
- , Brent R Stockwell
- , William C Hahn
- , Lynda Chin
- , Ronald A DePinho
- , Jesse S Boehm
- , Shuba Gopal
- , Alan Huang
- , David E Root
- , Barbara A Weir
- , Daniela S Gerhard
- , Jean Claude Zenklusen
- , Michael G Roth
- , Michael A White
- , John D Minna
- , John B MacMillan
- & Bruce A Posner
-
Research | | Open
-
Research | | Open
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
- Yilong Zou
- , Michael J. Palte
- , Amy A. Deik
- , Haoxin Li
- , John K. Eaton
- , Wenyu Wang
- , Yuen-Yi Tseng
- , Rebecca Deasy
- , Maria Kost-Alimova
- , Vlado Dančík
- , Elizaveta S. Leshchiner
- , Vasanthi S. Viswanathan
- , Sabina Signoretti
- , Toni K. Choueiri
- , Jesse S. Boehm
- , Bridget K. Wagner
- , John G. Doench
- , Clary B. Clish
- , Paul A. Clemons
- & Stuart L. Schreiber
-
Research | | Open
-
Research |
A precision oncology approach to the pharmacological targeting of mechanistic dependencies in neuroendocrine tumors
- Mariano J. Alvarez
- , Prem S. Subramaniam
- , Laura H. Tang
- , Adina Grunn
- , Mahalaxmi Aburi
- , Gabrielle Rieckhof
- , Elena V. Komissarova
- , Elizabeth A. Hagan
- , Lisa Bodei
- , Paul A. Clemons
- , Filemon S. Dela Cruz
- , Deepti Dhall
- , Daniel Diolaiti
- , Douglas A. Fraker
- , Afshin Ghavami
- , Daniel Kaemmerer
- , Charles Karan
- , Mark Kidd
- , Kyoung M. Kim
- , Hee C. Kim
- , Lakshmi P. Kunju
- , Ülo Langel
- , Zhong Li
- , Jeeyun Lee
- , Hai Li
- , Virginia LiVolsi
- , Roswitha Pfragner
- , Allison R. Rainey
- , Ronald B. Realubit
- , Helen Remotti
- , Jakob Regberg
- , Robert Roses
- , Anil Rustgi
- , Antonia R. Sepulveda
- , Stefano Serra
- , Chanjuan Shi
- , Xiaopu Yuan
- , Massimo Barberis
- , Roberto Bergamaschi
- , Arul M. Chinnaiyan
- , Tony Detre
- , Shereen Ezzat
- , Andrea Frilling
- , Merten Hommann
- , Dirk Jaeger
- , Michelle K. Kim
- , Beatrice S. Knudsen
- , Andrew L. Kung
- , Emer Leahy
- , David C. Metz
- , Jeffrey W. Milsom
- , Young S. Park
- , Diane Reidy-Lagunes
- , Stuart Schreiber
- , Kay Washington
- , Bertram Wiedenmann
- , Irvin Modlin
- & Andrea Califano
-
Reviews | | Open
Data-analysis strategies for image-based cell profiling
- Juan C Caicedo
- , Sam Cooper
- , Florian Heigwer
- , Scott Warchal
- , Peng Qiu
- , Csaba Molnar
- , Aliaksei S Vasilevich
- , Joseph D Barry
- , Harmanjit Singh Bansal
- , Oren Kraus
- , Mathias Wawer
- , Lassi Paavolainen
- , Markus D Herrmann
- , Mohammad Rohban
- , Jane Hung
- , Holger Hennig
- , John Concannon
- , Ian Smith
- , Paul A Clemons
- , Shantanu Singh
- , Paul Rees
- , Peter Horvath
- , Roger G Linington
- & Anne E Carpenter
-
Research |
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- Vasanthi S. Viswanathan
- , Matthew J. Ryan
- , Harshil D. Dhruv
- , Shubhroz Gill
- , Ossia M. Eichhoff
- , Brinton Seashore-Ludlow
- , Samuel D. Kaffenberger
- , John K. Eaton
- , Kenichi Shimada
- , Andrew J. Aguirre
- , Srinivas R. Viswanathan
- , Shrikanta Chattopadhyay
- , Pablo Tamayo
- , Wan Seok Yang
- , Matthew G. Rees
- , Sixun Chen
- , Zarko V. Boskovic
- , Sarah Javaid
- , Cherrie Huang
- , Xiaoyun Wu
- , Yuen-Yi Tseng
- , Elisabeth M. Roider
- , Dong Gao
- , James M. Cleary
- , Brian M. Wolpin
- , Jill P. Mesirov
- , Daniel A. Haber
- , Jeffrey A. Engelman
- , Jesse S. Boehm
- , Joanne D. Kotz
- , Cindy S. Hon
- , Yu Chen
- , William C. Hahn
- , Mitchell P. Levesque
- , John G. Doench
- , Michael E. Berens
- , Alykhan F. Shamji
- , Paul A. Clemons
- , Brent R. Stockwell
- & Stuart L. Schreiber
-
Research | | Open
Integrated genetic and pharmacologic interrogation of rare cancers
- Andrew L. Hong
- , Yuen-Yi Tseng
- , Glenn S. Cowley
- , Oliver Jonas
- , Jaime H. Cheah
- , Bryan D. Kynnap
- , Mihir B. Doshi
- , Coyin Oh
- , Stephanie C. Meyer
- , Alanna J. Church
- , Shubhroz Gill
- , Craig M. Bielski
- , Paula Keskula
- , Alma Imamovic
- , Sara Howell
- , Gregory V. Kryukov
- , Paul A. Clemons
- , Aviad Tsherniak
- , Francisca Vazquez
- , Brian D. Crompton
- , Alykhan F. Shamji
- , Carlos Rodriguez-Galindo
- , Katherine A. Janeway
- , Charles W. M. Roberts
- , Kimberly Stegmaier
- , Paul van Hummelen
- , Michael J. Cima
- , Robert S. Langer
- , Levi A. Garraway
- , Stuart L. Schreiber
- , David E. Root
- , William C. Hahn
- & Jesse S. Boehm
-
Research |
Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics
- Luc de Waal
- , Timothy A Lewis
- , Matthew G Rees
- , Aviad Tsherniak
- , Xiaoyun Wu
- , Peter S Choi
- , Lara Gechijian
- , Christina Hartigan
- , Patrick W Faloon
- , Mark J Hickey
- , Nicola Tolliday
- , Steven A Carr
- , Paul A Clemons
- , Benito Munoz
- , Bridget K Wagner
- , Alykhan F Shamji
- , Angela N Koehler
- , Monica Schenone
- , Alex B Burgin
- , Stuart L Schreiber
- , Heidi Greulich
- & Matthew Meyerson
-
Research |
Correlating chemical sensitivity and basal gene expression reveals mechanism of action
- Matthew G Rees
- , Brinton Seashore-Ludlow
- , Jaime H Cheah
- , Drew J Adams
- , Edmund V Price
- , Shubhroz Gill
- , Sarah Javaid
- , Matthew E Coletti
- , Victor L Jones
- , Nicole E Bodycombe
- , Christian K Soule
- , Benjamin Alexander
- , Ava Li
- , Philip Montgomery
- , Joanne D Kotz
- , C Suk-Yee Hon
- , Benito Munoz
- , Ted Liefeld
- , Vlado Dančík
- , Daniel A Haber
- , Clary B Clish
- , Joshua A Bittker
- , Michelle Palmer
- , Bridget K Wagner
- , Paul A Clemons
- , Alykhan F Shamji
- & Stuart L Schreiber
-
Research | | Open
A genetic basis for the variation in the vulnerability of cancer to DNA damage
- Brian D. Yard
- , Drew J. Adams
- , Eui Kyu Chie
- , Pablo Tamayo
- , Jessica S. Battaglia
- , Priyanka Gopal
- , Kevin Rogacki
- , Bradley E. Pearson
- , James Phillips
- , Daniel P. Raymond
- , Nathan A. Pennell
- , Francisco Almeida
- , Jaime H. Cheah
- , Paul A. Clemons
- , Alykhan Shamji
- , Craig D. Peacock
- , Stuart L. Schreiber
- , Peter S. Hammerman
- & Mohamed E. Abazeed
-
Research |
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors
- Nobutaka Kato
- , Eamon Comer
- , Tomoyo Sakata-Kato
- , Arvind Sharma
- , Manmohan Sharma
- , Micah Maetani
- , Jessica Bastien
- , Nicolas M. Brancucci
- , Joshua A. Bittker
- , Victoria Corey
- , David Clarke
- , Emily R. Derbyshire
- , Gillian L. Dornan
- , Sandra Duffy
- , Sean Eckley
- , Maurice A. Itoe
- , Karin M. J. Koolen
- , Timothy A. Lewis
- , Ping S. Lui
- , Amanda K. Lukens
- , Emily Lund
- , Sandra March
- , Elamaran Meibalan
- , Bennett C. Meier
- , Jacob A. McPhail
- , Branko Mitasev
- , Eli L. Moss
- , Morgane Sayes
- , Yvonne Van Gessel
- , Mathias J. Wawer
- , Takashi Yoshinaga
- , Anne-Marie Zeeman
- , Vicky M. Avery
- , Sangeeta N. Bhatia
- , John E. Burke
- , Flaminia Catteruccia
- , Jon C. Clardy
- , Paul A. Clemons
- , Koen J. Dechering
- , Jeremy R. Duvall
- , Michael A. Foley
- , Fabian Gusovsky
- , Clemens H. M. Kocken
- , Matthias Marti
- , Marshall L. Morningstar
- , Benito Munoz
- , Daniel E. Neafsey
- , Amit Sharma
- , Elizabeth A. Winzeler
- , Dyann F. Wirth
- , Christina A. Scherer
- & Stuart L. Schreiber
-
Research |
Niche-based screening identifies small-molecule inhibitors of leukemia stem cells
- Kimberly A Hartwell
- , Peter G Miller
- , Siddhartha Mukherjee
- , Alissa R Kahn
- , Alison L Stewart
- , David J Logan
- , Joseph M Negri
- , Mildred Duvet
- , Marcus Järås
- , Rishi Puram
- , Vlado Dancik
- , Fatima Al-Shahrour
- , Thomas Kindler
- , Zuzana Tothova
- , Shrikanta Chattopadhyay
- , Thomas Hasaka
- , Rajiv Narayan
- , Mingji Dai
- , Christina Huang
- , Sebastian Shterental
- , Lisa P Chu
- , J Erika Haydu
- , Jae Hung Shieh
- , David P Steensma
- , Benito Munoz
- , Joshua A Bittker
- , Alykhan F Shamji
- , Paul A Clemons
- , Nicola J Tolliday
- , Anne E Carpenter
- , D Gary Gilliland
- , Andrew M Stern
- , Malcolm A S Moore
- , David T Scadden
- , Stuart L Schreiber
- , Benjamin L Ebert
- & Todd R Golub
-
Reviews |
