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Amendments and Corrections | 17 May 2017
Correction: Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain
Nature Chemical Biology 13 , 691–691

Rights & permissionsfor article Correction: Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain . Opens in a new window.
Amendments and Corrections | 20 January 2016
Correction: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase
- Weiwei He
- , Ge Bai
- , Huihao Zhou
- , Na Wei
- , Nicholas M. White
- , Janelle Lauer
- , Huaqing Liu
- , Yi Shi
- , Calin Dan Dumitru
- , Karen Lettieri
- , Veronica Shubayev
- , Albena Jordanova
- , Velina Guergueltcheva
- , Patrick R. Griffin
- , Robert W. Burgess
- , Samuel L. Pfaff
- & Xiang-Lei Yang
Nature 532 , 402–402

Rights & permissionsfor article Correction: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase . Opens in a new window.
Research | 16 October 2020 | Open
Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6
Nature Communications 11 , 1–13

Rights & permissionsfor article Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6 . Opens in a new window.
Amendments and Corrections | 17 May 2017
Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain
Nature Chemical Biology 13 , 691–691

Rights & permissionsfor article Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain . Opens in a new window.
Research | 19 February 2020 | Open
A molecular switch regulating transcriptional repression and activation of PPARγ
- Jinsai Shang
- , Sarah A. Mosure
- , Jie Zheng
- , Richard Brust
- , Jared Bass
- , Ashley Nichols
- , Laura A. Solt
- , Patrick R. Griffin
- & Douglas J. Kojetin
Nature Communications 11 , 1–14

Rights & permissionsfor article A molecular switch regulating transcriptional repression and activation of PPARγ . Opens in a new window.
Research | 20 December 2019 | Open
Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ
Nature Communications 10 , 1–14

Rights & permissionsfor article Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ . Opens in a new window.
Reviews | 27 June 2019 | Open
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
- Glenn R. Masson
- , John E. Burke
- , Natalie G. Ahn
- , Ganesh S. Anand
- , Christoph Borchers
- , Sébastien Brier
- , George M. Bou-Assaf
- , John R. Engen
- , S. Walter Englander
- , Johan Faber
- , Rachel Garlish
- , Patrick R. Griffin
- , Michael L. Gross
- , Miklos Guttman
- , Yoshitomo Hamuro
- , Albert J. R. Heck
- , Damian Houde
- , Roxana E. Iacob
- , Thomas J. D. Jørgensen
- , Igor A. Kaltashov
- , Judith P. Klinman
- , Lars Konermann
- , Petr Man
- , Leland Mayne
- , Bruce D. Pascal
- , Dana Reichmann
- , Mark Skehel
- , Joost Snijder
- , Timothy S. Strutzenberg
- , Eric S. Underbakke
- , Cornelia Wagner
- , Thomas E. Wales
- , Benjamin T. Walters
- , David D. Weis
- , Derek J. Wilson
- , Patrick L. Wintrode
- , Zhongqi Zhang
- , Jie Zheng
- , David C. Schriemer
- & Kasper D. Rand
Nature Methods 16 , 595–602

Rights & permissionsfor article Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments . Opens in a new window.
Research | 9 January 2019 | Open
Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling
Nature Communications 10 , 1–12

Rights & permissionsfor article Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling . Opens in a new window.
Research | 18 December 2018 | Open
HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity
- Jie Zheng
- , Chen Wang
- , Mi Ra Chang
- , Swapnil C. Devarkar
- , Brandon Schweibenz
- , Gogce C. Crynen
- , Ruben D. Garcia-Ordonez
- , Bruce D. Pascal
- , Scott J. Novick
- , Smita S. Patel
- , Joseph Marcotrigiano
- & Patrick R. Griffin
Nature Communications 9 , 1–12

Rights & permissionsfor article HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity . Opens in a new window.
Research | 8 November 2018 | Open
A structural mechanism for directing corepressor-selective inverse agonism of PPARγ
- Richard Brust
- , Jinsai Shang
- , Jakob Fuhrmann
- , Sarah A. Mosure
- , Jared Bass
- , Andrew Cano
- , Zahra Heidari
- , Ian M. Chrisman
- , Michelle D. Nemetchek
- , Anne-Laure Blayo
- , Patrick R. Griffin
- , Theodore M. Kamenecka
- , Travis S. Hughes
- & Douglas J. Kojetin
Nature Communications 9 , 1–14

Rights & permissionsfor article A structural mechanism for directing corepressor-selective inverse agonism of PPARγ . Opens in a new window.
Research | 4 May 2018 | Open
Defining a conformational ensemble that directs activation of PPARγ
Nature Communications 9 , 1–16

Rights & permissionsfor article Defining a conformational ensemble that directs activation of PPARγ . Opens in a new window.
Research | 28 March 2018 | Open
The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma
- Nikolai Schleussner
- , Olaf Merkel
- , Mariantonia Costanza
- , Huan-Chang Liang
- , Franziska Hummel
- , Chiara Romagnani
- , Pawel Durek
- , Ioannis Anagnostopoulos
- , Michael Hummel
- , Korinna Jöhrens
- , Antonia Niedobitek
- , Patrick R. Griffin
- , Roberto Piva
- , Henrike L. Sczakiel
- , Wilhelm Woessmann
- , Christine Damm-Welk
- , Christian Hinze
- , Dagmar Stoiber
- , Bernd Gillissen
- , Suzanne D. Turner
- , Eva Kaergel
- , Linda von Hoff
- , Michael Grau
- , Georg Lenz
- , Bernd Dörken
- , Claus Scheidereit
- , Lukas Kenner
- , Martin Janz
- & Stephan Mathas
Leukemia 32 , 1994–2007

Rights & permissionsfor article The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma . Opens in a new window.
Research | 6 April 2018 | Open
Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2
- Krishna Chinthalapudi
- , Vinay Mandati
- , Jie Zheng
- , Andrew J. Sharff
- , Gerard Bricogne
- , Patrick R. Griffin
- , Joseph Kissil
- & Tina Izard
Nature Communications 9 , 1–10

Rights & permissionsfor article Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2 . Opens in a new window.
Research | 13 October 2017 | Open
HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions
- Jie Zheng
- , Mi Ra Chang
- , Ryan E. Stites
- , Yong Wang
- , John B. Bruning
- , Bruce D. Pascal
- , Scott J. Novick
- , Ruben D. Garcia-Ordonez
- , Keith R. Stayrook
- , Michael J. Chalmers
- , Jeffrey A. Dodge
- & Patrick R. Griffin
Nature Communications 8 , 1–13

Rights & permissionsfor article HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions . Opens in a new window.
Research | 29 September 2017 | Open
SPA70 is a potent antagonist of human pregnane X receptor
- Wenwei Lin
- , Yue-Ming Wang
- , Sergio C. Chai
- , Lili Lv
- , Jie Zheng
- , Jing Wu
- , Qijun Zhang
- , Yong-Dong Wang
- , Patrick R. Griffin
- & Taosheng Chen
Nature Communications 8 , 1–14

Rights & permissionsfor article SPA70 is a potent antagonist of human pregnane X receptor . Opens in a new window.
Research | 17 May 2017 | Open
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand
- Xianjun Zhang
- , Fei Zhao
- , Yiran Wu
- , Jun Yang
- , Gye Won Han
- , Suwen Zhao
- , Andrii Ishchenko
- , Lintao Ye
- , Xi Lin
- , Kang Ding
- , Venkatasubramanian Dharmarajan
- , Patrick R. Griffin
- , Cornelius Gati
- , Garrett Nelson
- , Mark S. Hunter
- , Michael A. Hanson
- , Vadim Cherezov
- , Raymond C. Stevens
- , Wenfu Tan
- , Houchao Tao
- & Fei Xu
Nature Communications 8 , 1–10

Rights & permissionsfor article Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand . Opens in a new window.
Research | 17 May 2017
Structure of the full-length glucagon class B G-protein-coupled receptor
- Haonan Zhang
- , Anna Qiao
- , Dehua Yang
- , Linlin Yang
- , Antao Dai
- , Chris de Graaf
- , Steffen Reedtz-Runge
- , Venkatasubramanian Dharmarajan
- , Hui Zhang
- , Gye Won Han
- , Thomas D. Grant
- , Raymond G. Sierra
- , Uwe Weierstall
- , Garrett Nelson
- , Wei Liu
- , Yanhong Wu
- , Limin Ma
- , Xiaoqing Cai
- , Guangyao Lin
- , Xiaoai Wu
- , Zhi Geng
- , Yuhui Dong
- , Gaojie Song
- , Patrick R. Griffin
- , Jesper Lau
- , Vadim Cherezov
- , Huaiyu Yang
- , Michael A. Hanson
- , Raymond C. Stevens
- , Qiang Zhao
- , Hualiang Jiang
- , Ming-Wei Wang
- & Beili Wu
Nature 546 , 259–264

Rights & permissionsfor article Structure of the full-length glucagon class B G-protein-coupled receptor . Opens in a new window.
Research | 27 June 2016
Neddylation requires glycyl-tRNA synthetase to protect activated E2
- Zhongying Mo
- , Qian Zhang
- , Ze Liu
- , Janelle Lauer
- , Yi Shi
- , Litao Sun
- , Patrick R Griffin
- & Xiang-Lei Yang
Nature Structural & Molecular Biology 23 , 730–737

Rights & permissionsfor article Neddylation requires glycyl-tRNA synthetase to protect activated E2 . Opens in a new window.
Research | 21 November 2016
Full antagonism of the estrogen receptor without a prototypical ligand side chain
Nature Chemical Biology 13 , 111–118

Rights & permissionsfor article Full antagonism of the estrogen receptor without a prototypical ligand side chain . Opens in a new window.
Research | 10 August 2015
Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling
- Feng Zhang
- , Jian Yao
- , Jiyuan Ke
- , Li Zhang
- , Vinh Q. Lam
- , Xiu-Fang Xin
- , X. Edward Zhou
- , Jian Chen
- , Joseph Brunzelle
- , Patrick R. Griffin
- , Mingguo Zhou
- , H. Eric Xu
- , Karsten Melcher
- & Sheng Yang He
Nature 525 , 269–273

Rights & permissionsfor article Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling . Opens in a new window.
Research | 21 October 2015
CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase
- Weiwei He
- , Ge Bai
- , Huihao Zhou
- , Na Wei
- , Nicholas M. White
- , Janelle Lauer
- , Huaqing Liu
- , Yi Shi
- , Calin Dan Dumitru
- , Karen Lettieri
- , Veronica Shubayev
- , Albena Jordanova
- , Velina Guergueltcheva
- , Patrick R. Griffin
- , Robert W. Burgess
- , Samuel L. Pfaff
- & Xiang-Lei Yang
Nature 526 , 710–714

Rights & permissionsfor article CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase . Opens in a new window.
Research | 22 July 2015
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
- Yanyong Kang
- , X. Edward Zhou
- , Xiang Gao
- , Yuanzheng He
- , Wei Liu
- , Andrii Ishchenko
- , Anton Barty
- , Thomas A. White
- , Oleksandr Yefanov
- , Gye Won Han
- , Qingping Xu
- , Parker W. de Waal
- , Jiyuan Ke
- , M. H. Eileen Tan
- , Chenghai Zhang
- , Arne Moeller
- , Graham M. West
- , Bruce D. Pascal
- , Ned Van Eps
- , Lydia N. Caro
- , Sergey A. Vishnivetskiy
- , Regina J. Lee
- , Kelly M. Suino-Powell
- , Xin Gu
- , Kuntal Pal
- , Jinming Ma
- , Xiaoyong Zhi
- , Sébastien Boutet
- , Garth J. Williams
- , Marc Messerschmidt
- , Cornelius Gati
- , Nadia A. Zatsepin
- , Dingjie Wang
- , Daniel James
- , Shibom Basu
- , Shatabdi Roy-Chowdhury
- , Chelsie E. Conrad
- , Jesse Coe
- , Haiguang Liu
- , Stella Lisova
- , Christopher Kupitz
- , Ingo Grotjohann
- , Raimund Fromme
- , Yi Jiang
- , Minjia Tan
- , Huaiyu Yang
- , Jun Li
- , Meitian Wang
- , Zhong Zheng
- , Dianfan Li
- , Nicole Howe
- , Yingming Zhao
- , Jörg Standfuss
- , Kay Diederichs
- , Yuhui Dong
- , Clinton S. Potter
- , Bridget Carragher
- , Martin Caffrey
- , Hualiang Jiang
- , Henry N. Chapman
- , John C. H. Spence
- , Petra Fromme
- , Uwe Weierstall
- , Oliver P. Ernst
- , Vsevolod Katritch
- , Vsevolod V. Gurevich
- , Patrick R. Griffin
- , Wayne L. Hubbell
- , Raymond C. Stevens
- , Vadim Cherezov
- , Karsten Melcher
- & H. Eric Xu
Nature 523 , 561–567

Rights & permissionsfor article Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser . Opens in a new window.
Research | 31 July 2015 | Open
Conformational states of the full-length glucagon receptor
- Linlin Yang
- , Dehua Yang
- , Chris de Graaf
- , Arne Moeller
- , Graham M. West
- , Venkatasubramanian Dharmarajan
- , Chong Wang
- , Fai Y. Siu
- , Gaojie Song
- , Steffen Reedtz-Runge
- , Bruce D. Pascal
- , Beili Wu
- , Clinton S. Potter
- , Hu Zhou
- , Patrick R. Griffin
- , Bridget Carragher
- , Huaiyu Yang
- , Ming-Wei Wang
- , Raymond C. Stevens
- & Hualiang Jiang
Nature Communications 6 , 1–13

Rights & permissionsfor article Conformational states of the full-length glucagon receptor . Opens in a new window.
Research | 1 December 2015 | Open
Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects
- Hongkai Zhang
- , Emmanuel Sturchler
- , Jiang Zhu
- , Ainhoa Nieto
- , Philip A. Cistrone
- , Jia Xie
- , LinLing He
- , Kyungmoo Yea
- , Teresa Jones
- , Rachel Turn
- , Peter S. Di Stefano
- , Patrick R. Griffin
- , Philip E. Dawson
- , Patricia H. McDonald
- & Richard A. Lerner
Nature Communications 6 , 1–13

Rights & permissionsfor article Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects . Opens in a new window.
Research | 12 June 2015
Pharmacological repression of PPARγ promotes osteogenesis
Nature Communications 6 , 1–7

Rights & permissionsfor article Pharmacological repression of PPARγ promotes osteogenesis . Opens in a new window.
Research | 16 October 2015
Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3
- Li-Hua Zhao
- , X Edward Zhou
- , Wei Yi
- , Zhongshan Wu
- , Yue Liu
- , Yanyong Kang
- , Li Hou
- , Parker W de Waal
- , Suling Li
- , Yi Jiang
- , Adrian Scaffidi
- , Gavin R Flematti
- , Steven M Smith
- , Vinh Q Lam
- , Patrick R Griffin
- , Yonghong Wang
- , Jiayang Li
- , Karsten Melcher
- & H Eric Xu
Cell Research 25 , 1219–1236

Rights & permissionsfor article Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3 . Opens in a new window.
Research | 20 August 2015 | Open
Structural mechanism for signal transduction in RXR nuclear receptor heterodimers
Nature Communications 6 , 1–14

Rights & permissionsfor article Structural mechanism for signal transduction in RXR nuclear receptor heterodimers . Opens in a new window.
Research | 7 April 2014
An alternate binding site for PPARγ ligands
Nature Communications 5 , 1–13

Rights & permissionsfor article An alternate binding site for PPARγ ligands . Opens in a new window.
Research | 22 July 2010
Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
Nature 466 , 451–456

Rights & permissionsfor article Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5 . Opens in a new window.
Research | 6 July 1995
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
- Donald W. Nicholson
- , Ambereen Ali
- , Nancy A. Thornberry
- , John P. Vaillancourt
- , Connie K. Ding
- , Michel Gallant
- , Yves Gareau
- , Patrick R. Griffin
- , Marc Labelle
- , Yuri A. Lazebnik
- , Neil A. Munday
- , Sayyaparaju M. Raju
- , Mark E. Smulson
- , Ting-Ting Yamin
- , Violeta L. Yu
- & Douglas K. Miller
Nature 376 , 37–43

Rights & permissionsfor article Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis . Opens in a new window.
Research | 15 April 2012
Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation
Nature Structural & Molecular Biology 19 , 532–537

Rights & permissionsfor article Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation . Opens in a new window.
Research | 4 September 2011
Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation
- Jang Hyun Choi
- , Alexander S. Banks
- , Theodore M. Kamenecka
- , Scott A. Busby
- , Michael J. Chalmers
- , Naresh Kumar
- , Dana S. Kuruvilla
- , Youseung Shin
- , Yuanjun He
- , John B. Bruning
- , David P. Marciano
- , Michael D. Cameron
- , Dina Laznik
- , Michael J. Jurczak
- , Stephan C. Schürer
- , Dušica Vidović
- , Gerald I. Shulman
- , Bruce M. Spiegelman
- & Patrick R. Griffin
Nature 477 , 477–481

Rights & permissionsfor article Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation . Opens in a new window.
Research | 10 April 2011
DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex
- Jun Zhang
- , Michael J Chalmers
- , Keith R Stayrook
- , Lorri L Burris
- , Yongjun Wang
- , Scott A Busby
- , Bruce D Pascal
- , Ruben D Garcia-Ordonez
- , John B Bruning
- , Monica A Istrate
- , Douglas J Kojetin
- , Jeffrey A Dodge
- , Thomas P Burris
- & Patrick R Griffin
Nature Structural & Molecular Biology 18 , 556–563

Rights & permissionsfor article DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex . Opens in a new window.
Research | 25 May 2011
A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
Nature 474 , 506–510

Rights & permissionsfor article A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects . Opens in a new window.
Research | 17 April 2011
Suppression of T_H17 differentiation and autoimmunity by a synthetic ROR ligand
- Laura A. Solt
- , Naresh Kumar
- , Philippe Nuhant
- , Yongjun Wang
- , Janelle L. Lauer
- , Jin Liu
- , Monica A. Istrate
- , Theodore M. Kamenecka
- , William R. Roush
- , Dušica Vidović
- , Stephan C. Schürer
- , Jihong Xu
- , Gail Wagoner
- , Paul D. Drew
- , Patrick R. Griffin
- & Thomas P. Burris
Nature 472 , 491–494

Rights & permissionsfor article Suppression of T<sub>H</sub>17 differentiation and autoimmunity by a synthetic ROR ligand . Opens in a new window.

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Correction: Corrigendum: Full antagonism of the estrogen receptor without a prototypical ligand side chain

Correction: Corrigendum: CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase

Multivalent interactions drive nucleosome binding and efficient chromatin deacetylation by SIRT6

Erratum: Full antagonism of the estrogen receptor without a prototypical ligand side chain

A molecular switch regulating transcriptional repression and activation of PPARγ

Definition of functionally and structurally distinct repressive states in the nuclear receptor PPARγ

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

Histone H3 binding to the PHD1 domain of histone demethylase KDM5A enables active site remodeling

HDX-MS reveals dysregulated checkpoints that compromise discrimination against self RNA during RIG-I mediated autoimmunity

A structural mechanism for directing corepressor-selective inverse agonism of PPARγ

Defining a conformational ensemble that directs activation of PPARγ

The AP-1-BATF and -BATF3 module is essential for growth, survival and TH17/ILC3 skewing of anaplastic large cell lymphoma

Lipid binding promotes the open conformation and tumor-suppressive activity of neurofibromin 2

HDX reveals the conformational dynamics of DNA sequence specific VDR co-activator interactions

SPA70 is a potent antagonist of human pregnane X receptor

Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand

Structure of the full-length glucagon class B G-protein-coupled receptor

Neddylation requires glycyl-tRNA synthetase to protect activated E2

Full antagonism of the estrogen receptor without a prototypical ligand side chain

Structural basis of JAZ repression of MYC transcription factors in jasmonate signalling

CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase

Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser

Conformational states of the full-length glucagon receptor

Autocrine selection of a GLP-1R G-protein biased agonist with potent antidiabetic effects

Pharmacological repression of PPARγ promotes osteogenesis

Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3

Structural mechanism for signal transduction in RXR nuclear receptor heterodimers

An alternate binding site for PPARγ ligands

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Antidiabetic phospholipid–nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation

Antidiabetic actions of a non-agonist PPARγ ligand blocking Cdk5-mediated phosphorylation

DNA binding alters coactivator interaction surfaces of the intact VDR–RXR complex

A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects

Suppression of T_H17 differentiation and autoimmunity by a synthetic ROR ligand

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