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Research | 20 October 2020 | Open
Neonatal monocytes demonstrate impaired homeostatic extravasation into a microphysiological human vascular model
- Guzman Sanchez-Schmitz
- , Elena Morrocchi
- , Mitchell Cooney
- , Dheeraj Soni
- , Rahima Khatun
- , Paolo Palma
- , David J. Dowling
- & Ofer Levy
Scientific Reports 10 , 1–14

Rights & permissionsfor article Neonatal monocytes demonstrate impaired homeostatic extravasation into a microphysiological human vascular model . Opens in a new window.
1 April 1999
Impaired Innate Immunity in the Newborn: Newborn Neutrophils Are Deficient in Bactericidal/Permeability-Increasing Protein (BPI)
- Ofer Levy
- , Sara Martin
- , Eric C Eichenwald
- , Steve Carroll
- , Kelly Lee
- , Donald Goldmann
- & Grace M Thorne
Pediatric Research 45 , 208–208

Rights & permissionsfor article Impaired Innate Immunity in the Newborn: Newborn Neutrophils Are Deficient in Bactericidal/Permeability-Increasing Protein (BPI) . Opens in a new window.
Research | 2 October 2019
Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro
- Tobias Strunk
- , Simon D. van Haren
- , Julie Hibbert
- , Matthew Pettengill
- , Al Ozonoff
- , Jop Jans
- , Simone S. Schüller
- , David Burgner
- , Ofer Levy
- & Andrew J. Currie
Pediatric Research 88 , 717–725

Rights & permissionsfor article Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro . Opens in a new window.
6 November 2013
Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines
- Ofer Levy
- & Mihai G. Netea
Pediatric Research 75 , 184–188

Rights & permissionsfor article Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines . Opens in a new window.
1 June 2002
Impaired Innate Immunity at Birth: Deficiency of Bactericidal/Permeability-Increasing Protein (BPI) in the Neutrophils of Newborns
- Ofer Levy
Pediatric Research 51 , 667–669

Rights & permissionsfor article Impaired Innate Immunity at Birth: Deficiency of Bactericidal/Permeability-Increasing Protein (BPI) in the Neutrophils of Newborns . Opens in a new window.
1 April 2004
Genetic Screening for Susceptibility to Infection in the NICU Setting: Commentary on the article by Ahrens et al. on page 652
- Ofer Levy
Pediatric Research 55 , 546–548

Rights & permissionsfor article Genetic Screening for Susceptibility to Infection in the NICU Setting: Commentary on the article by Ahrens et al. on page 652 . Opens in a new window.
11 May 2012 | Open
Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation
Pediatric Research 72 , 203–211

Rights & permissionsfor article Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation . Opens in a new window.
1 December 2010
Human Neonatal Peripheral Blood Leukocytes Demonstrate Pathogen-Specific Coordinate Expression of TLR2, TLR4/MD2, and MyD88 During Bacterial Infection In Vivo
- Jin-Ping Zhang
- , Yi Yang
- , Ofer Levy
- & Chao Chen
Pediatric Research 68 , 479–483

Rights & permissionsfor article Human Neonatal Peripheral Blood Leukocytes Demonstrate Pathogen-Specific Coordinate Expression of TLR2, TLR4/MD2, and MyD88 During Bacterial Infection In Vivo . Opens in a new window.
1 August 2006
Innate Immunity of the Human Newborn Is Polarized Toward a High Ratio of IL-6/TNF-α Production In Vitro and In Vivo
Pediatric Research 60 , 205–209

Rights & permissionsfor article Innate Immunity of the Human Newborn Is Polarized Toward a High Ratio of IL-6/TNF-α Production In Vitro and In Vivo . Opens in a new window.
29 March 2012
Responsiveness of human monocytes to the commensal bacterium Staphylococcus epidermidis develops late in gestation
- Tobias Strunk
- , Amy Prosser
- , Ofer Levy
- , Victoria Philbin
- , Karen Simmer
- , Dorota Doherty
- , Adrian Charles
- , Peter Richmond
- , David Burgner
- & Andrew Currie
Pediatric Research 72 , 10–18

Rights & permissionsfor article Responsiveness of human monocytes to the commensal bacterium Staphylococcus epidermidis develops late in gestation . Opens in a new window.
15 February 2011
Challenges in infant immunity: implications for responses to infection and vaccines
- Mercy PrabhuDas
- , Becky Adkins
- , Hayley Gans
- , Christopher King
- , Ofer Levy
- , Octavio Ramilo
- & Claire-Anne Siegrist
Nature Immunology 12 , 189–194

Rights & permissionsfor article Challenges in infant immunity: implications for responses to infection and vaccines . Opens in a new window.
News and Views | 18 August 2011
Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake
Nature Immunology 12 , 805–808

Rights & permissionsfor article Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake . Opens in a new window.
Reviews | 5 November 2019
Immunometabolic approaches to prevent, detect, and treat neonatal sepsis
Pediatric Research 87 , 399–405

Rights & permissionsfor article Immunometabolic approaches to prevent, detect, and treat neonatal sepsis . Opens in a new window.
Research | 12 March 2019 | Open
Dynamic molecular changes during the first week of human life follow a robust developmental trajectory
- Amy H. Lee
- , Casey P. Shannon
- , Nelly Amenyogbe
- , Tue B. Bennike
- , Joann Diray-Arce
- , Olubukola T. Idoko
- , Erin E. Gill
- , Rym Ben-Othman
- , William S. Pomat
- , Simon D. van Haren
- , Kim-Anh Lê Cao
- , Momoudou Cox
- , Alansana Darboe
- , Reza Falsafi
- , Davide Ferrari
- , Daniel J. Harbeson
- , Daniel He
- , Cai Bing
- , Samuel J. Hinshaw
- , Jorjoh Ndure
- , Jainaba Njie-Jobe
- , Matthew A. Pettengill
- , Peter C. Richmond
- , Rebecca Ford
- , Gerard Saleu
- , Geraldine Masiria
- , John Paul Matlam
- , Wendy Kirarock
- , Elishia Roberts
- , Mehrnoush Malek
- , Guzmán Sanchez-Schmitz
- , Amrit Singh
- , Asimenia Angelidou
- , Kinga K. Smolen
- , Diana Vo
- , Ken Kraft
- , Kerry McEnaney
- , Sofia Vignolo
- , Arnaud Marchant
- , Ryan R. Brinkman
- , Al Ozonoff
- , Robert E. W. Hancock
- , Anita H. J. van den Biggelaar
- , Hanno Steen
- , Scott J. Tebbutt
- , Beate Kampmann
- , Ofer Levy
- & Tobias R. Kollmann
Nature Communications 10 , 1–14

Rights & permissionsfor article Dynamic molecular changes during the first week of human life follow a robust developmental trajectory . Opens in a new window.
10 January 2017
Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns
- Esther M. Speer
- , David J. Dowling
- , Lukasz S. Ozog
- , Jianjin Xu
- , Jie Yang
- , Geetika Kennady
- & Ofer Levy
Pediatric Research 81 , 806–816

Rights & permissionsfor article Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns . Opens in a new window.
Reviews | 9 May 2016
Harnessing the beneficial heterologous effects of vaccination
Nature Reviews Immunology 16 , 392–400

Rights & permissionsfor article Harnessing the beneficial heterologous effects of vaccination . Opens in a new window.
1 May 2009
Developmental Biology of the Innate Immune Response: Implications for Neonatal and Infant Vaccine Development
- Victoria Jane Philbin
- & Ofer Levy
Pediatric Research 65 , 98–105

Rights & permissionsfor article Developmental Biology of the Innate Immune Response: Implications for Neonatal and Infant Vaccine Development . Opens in a new window.
Reviews | 1 May 2007
Innate immunity of the newborn: basic mechanisms and clinical correlates
- Ofer Levy
Nature Reviews Immunology 7 , 379–390

Rights & permissionsfor article Innate immunity of the newborn: basic mechanisms and clinical correlates . Opens in a new window.
1 August 2009
Endotoxin-Directed Innate Immunity in Tracheal Aspirates of Mechanically Ventilated Human Neonates
- Katheryn E Nathe
- , Richard Parad
- , Linda J Van Marter
- , Cara A Lund
- , Eugénie E Suter
- , Sonia Hernandez-Diaz
- , Elizabeth B G Boush
- , Eva Ikonomu
- , Leighanne Gallington
- , Jo Ann Morey
- , Alenka M Zeman
- , Meaghan McNamara
- & Ofer Levy
Pediatric Research 66 , 191–196

Rights & permissionsfor article Endotoxin-Directed Innate Immunity in Tracheal Aspirates of Mechanically Ventilated Human Neonates . Opens in a new window.

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Neonatal monocytes demonstrate impaired homeostatic extravasation into a microphysiological human vascular model

Impaired Innate Immunity in the Newborn: Newborn Neutrophils Are Deficient in Bactericidal/Permeability-Increasing Protein (BPI)

Cyclic AMP in human preterm infant blood is associated with increased TLR-mediated production of acute-phase and anti-inflammatory cytokines in vitro

Innate immune memory: implications for development of pediatric immunomodulatory agents and adjuvanted vaccines

Impaired Innate Immunity at Birth: Deficiency of Bactericidal/Permeability-Increasing Protein (BPI) in the Neutrophils of Newborns

Genetic Screening for Susceptibility to Infection in the NICU Setting: Commentary on the article by Ahrens et al. on page 652

Innate immune activation in neonatal tracheal aspirates suggests endotoxin-driven inflammation

Human Neonatal Peripheral Blood Leukocytes Demonstrate Pathogen-Specific Coordinate Expression of TLR2, TLR4/MD2, and MyD88 During Bacterial Infection In Vivo

Innate Immunity of the Human Newborn Is Polarized Toward a High Ratio of IL-6/TNF-α Production In Vitro and In Vivo

Responsiveness of human monocytes to the commensal bacterium Staphylococcus epidermidis develops late in gestation

Challenges in infant immunity: implications for responses to infection and vaccines

Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake

Immunometabolic approaches to prevent, detect, and treat neonatal sepsis

Dynamic molecular changes during the first week of human life follow a robust developmental trajectory

Pentoxifylline inhibits TLR- and inflammasome-mediated in vitro inflammatory cytokine production in human blood with greater efficacy and potency in newborns

Harnessing the beneficial heterologous effects of vaccination

Developmental Biology of the Innate Immune Response: Implications for Neonatal and Infant Vaccine Development

Innate immunity of the newborn: basic mechanisms and clinical correlates

Endotoxin-Directed Innate Immunity in Tracheal Aspirates of Mechanically Ventilated Human Neonates

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